Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Hai M Nguyen"'
Autor:
Phuong T Nguyen, Hai M Nguyen, Karen M Wagner, Robert G Stewart, Vikrant Singh, Parashar Thapa, Yi-Je Chen, Mark W Lillya, Anh Tuan Ton, Richard Kondo, Andre Ghetti, Michael W Pennington, Bruce Hammock, Theanne N Griffith, Jon T Sack, Heike Wulff, Vladimir Yarov-Yarovoy
Publikováno v:
eLife, Vol 11 (2022)
The voltage-gated sodium NaV1.7 channel plays a key role as a mediator of action potential propagation in C-fiber nociceptors and is an established molecular target for pain therapy. ProTx-II is a potent and moderately selective peptide toxin from ta
Externí odkaz:
https://doaj.org/article/61a7e4bc52cf45b98b9c1e6f378c835a
Autor:
Ruth D. Lee, Yi-Je Chen, Hai M. Nguyen, Latika Singh, Connor J. Dietrich, Benjamin R. Pyles, Yanjun Cui, Jonathan R. Weinstein, Heike Wulff
Publikováno v:
Translational Stroke Research.
Senicapoc, a small molecule inhibitor of the calcium-activated potassium channel KCa3.1, was safe and well-tolerated in clinical trials for sickle cell anemia. We previously reported proof-of-concept data suggesting that both pharmacological inhibiti
Autor:
Sharan R, Srinivasan, Haoran, Huang, Wei-Chih, Chang, Joshua A, Nasburg, Hai M, Nguyen, Tim, Strassmaier, Heike, Wulff, Vikram G, Shakkottai
Publikováno v:
Molecular pharmacology, vol 102, iss 1
Mol Pharmacol
Mol Pharmacol
Impaired cerebellar Purkinje neuron firing resulting from reduced expression of large-conductance calcium-activated potassium (BK) channels is a consistent feature in models of inherited neurodegenerative spinocerebellar ataxia (SCA). Restoring BK ch
Publikováno v:
F1000Research, Vol 8 (2019)
As their name implies, cation channels allow the regulated flow of cations such as sodium, potassium, calcium, and magnesium across cellular and intracellular membranes. Cation channels have long been known for their fundamental roles in controlling
Externí odkaz:
https://doaj.org/article/aad21d5191d24efba4b7e46aa8413cae
Publikováno v:
Climate, Vol 3, Iss 4, Pp 999-1017 (2015)
The fraction of land area over the Continental United States experiencing extreme hot and dry conditions has been increasing over the past several decades, consistent with expectation from anthropogenic climate change. A clear concurrent change in pr
Externí odkaz:
https://doaj.org/article/7a60e63cde6142f5bd47dde4b1b78a8e
Autor:
Hai M Nguyen, Phuong T Nguyen, Karen M Wagner, Robert G Stewart, Vikrant Singh, Parashar Thapa, Yi-Je Chen, Mark W Lillya, Anh Tuan Ton, Richard Kondo, Andre Ghetti, Michael W Pennington, Bruce Hammock, Theanne N Griffith, Jon T Sack, Heike Wulff, Vladimir Yarov-Yarovoy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33893d32f016b01de0ad9310c1b61a77
https://doi.org/10.7554/elife.81727.sa2
https://doi.org/10.7554/elife.81727.sa2
Autor:
Hai M Nguyen, Phuong T Nguyen, Karen M Wagner, Robert G Stewart, Vikrant Singh, Parashar Thapa, Yi-Je Chen, Mark W Lillya, Anh Tuan Ton, Richard Kondo, Andre Ghetti, Michael W Pennington, Bruce Hammock, Theanne N Griffith, Jon T Sack, Heike Wulff, Vladimir Yarov-Yarovoy
The voltage-gated sodium NaV1.7 channel plays a key role as a mediator of action potential propagation in C-fiber nociceptors and is an established molecular target for pain therapy. ProTx-II is a potent and moderately selective peptide toxin from ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0988b85ef375b455a45538fdc58e6c47
https://escholarship.org/uc/item/35r029z1
https://escholarship.org/uc/item/35r029z1
Autor:
Longtao Wu, David D. Morabito, Joaquim P. Teixeira, Lei Huang, Hai M. Nguyen, Hui Su, Melissa A. Soriano, Lei Pan, Daniel S. Kahan, Rohini Bhawar
Publikováno v:
Radio Science. 57
Autor:
Phuong T. Nguyen, Hai M. Nguyen, Karen M. Wagner, Robert G. Stewart, Vikrant Singh, Parashar Thapa, Yi-Je Chen, Mark W. Lillya, Anh Tuan Ton, Richard Kondo, Andre Ghetti, Michael W. Pennington, Bruce Hammock, Theanne N. Griffith, Jon T. Sack, Heike Wulff, Vladimir Yarov-Yarovoy
The voltage-gated sodium NaV1.7 channel plays a key role as a mediator of action potential propagation in C-fiber nociceptors and is an established molecular target for pain therapy. ProTx-II is a potent and moderately selective peptide toxin from ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d947d4b583c02645779462fd248962
https://doi.org/10.1101/2022.07.21.500925
https://doi.org/10.1101/2022.07.21.500925
Autor:
Thomas Kyllo, Vikrant Singh, Heesung Shim, Singh Latika, Hai M. Nguyen, Yi-Je Chen, Ellen Terry, Heike Wulff, Jeffrey D. Erickson
Publikováno v:
Neuropharmacology. 224:109349
Epileptogenic seizures, or status epilepticus (SE), leads to excitotoxic injury in hippocampal and limbic neurons in the kainic acid (KA) animal model of temporal lobe epilepsy (TLE). Here, we have further characterized neural activity regulated meth