Zobrazeno 1 - 10
of 3 661
pro vyhledávání: '"Hai JIN"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Currently, even the most effective anti-cancer therapies are often limited by the development of drug resistance and tumor relapse, which is a major challenge facing current cancer research. A deep understanding of the molecular and biochemi
Externí odkaz:
https://doaj.org/article/25e4b951c5084cd382a309289391e41d
Autor:
Xinxing Li, Tao Liu, Antonella Bacchiocchi, Mengxing Li, Wen Cheng, Tobias Wittkop, Fernando L Mendez, Yingyu Wang, Paul Tang, Qianqian Yao, Marcus W Bosenberg, Mario Sznol, Qin Yan, Malek Faham, Li Weng, Ruth Halaban, Hai Jin, Zhiqian Hu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2188-2209 (2024)
Abstract While whole genome sequencing (WGS) of cell-free DNA (cfDNA) holds enormous promise for detection of molecular residual disease (MRD), its performance is limited by WGS error rate. Here we introduce AccuScan, an efficient cfDNA WGS technolog
Externí odkaz:
https://doaj.org/article/61e8893361234a0aaada760b5863e691
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundThe Magnesium depletion score (MDS) serves as a novel metric for quantifying magnesium deficiency in the human body, comprehensively assessing four indicators: diuretic use, proton pump inhibitor use, estimated glomerular filtration rate, a
Externí odkaz:
https://doaj.org/article/4dc5fb13f4ad41d8b4c4e8a5ba5056be
Autor:
Wen Ding, Shijun Bao, Qingwei Zhao, Wei Hao, Kai Fang, Yanlan Xiao, Xiaoting Lin, Zhemeng Zhao, Xinyi Xu, Xinyue Cui, Xiwen Yang, Liuhuan Yao, Hai Jin, Kun Zhang, Jiaming Guo
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Lung cancer (LC) is the leading cause of cancer‐related mortality worldwide. Radiotherapy is the main component of LC treatment; however, its efficacy is often limited by radioresistance development, resulting in unsatisfactory clinical ou
Externí odkaz:
https://doaj.org/article/3fdab54c63dd4509900f274742a9e294
Autor:
Yuwei Han, Guangzhi Hao, Song Han, Tingzhun Zhu, Yushu Dong, Ligang Chen, Xinyu Yang, Xiaoming Li, Hai Jin, Guobiao Liang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveThis study aims to investigate the inhibitory effect of Polydatin (PD) on endoplasmic reticulum (ER) stress following subarachnoid hemorrhage (SAH) and to elucidate the underlying mechanisms.MethodsA standard intravascular puncture model was
Externí odkaz:
https://doaj.org/article/5c4c0df3ef8043be91ea03573af237e1
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Media bias widely exists in the articles published by news media, influencing their readers’ perceptions, and bringing prejudice or injustice to society. However, current analysis methods usually rely on human efforts or only focus on a sp
Externí odkaz:
https://doaj.org/article/e231404adf1e46d8891084d8763607d1
Autor:
Yi Wang, Xiaolong Fu, Li Zeng, Yan Hu, Rongyang Gao, Siting Xian, Songjie Liao, Jianxiang Huang, Yonggang Yang, Jilong Liu, Hai Jin, James Klaunig, Yuanfu Lu, Shaoyu Zhou
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Nuclear factor erythroid 2-related factor-2 (Nrf2) antioxidant signaling is involved in liver protection, but this generalization overlooks conflicting studies indicating that Nrf2 effects are not necessarily hepatoprotective. The role of Nr
Externí odkaz:
https://doaj.org/article/437d2c14bca24a698e51ff7682440b0b
Publikováno v:
Journal of Social Computing, Vol 5, Iss 1, Pp 15-35 (2024)
Media power, the impact that media have on public opinion and perspectives, plays a significant role in maintaining internal stability, exerting external influence, and shaping international dynamics for nations /regions. However, prior research has
Externí odkaz:
https://doaj.org/article/a36cff8f82e54794ad2950367434ebad
Autor:
Minglin Zhang, Zhiyuan Ma, Zhiqiang Yi, Hu Wang, Jiaxing Zhu, Guorong Wen, Hai Jin, Jiaxing An, Zilin Deng, Biguang Tuo, Taolang Li, Xuemei Liu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Solute carrier family 26 member 9 (SLC26A9) is a member of the Slc26a family of multifunctional anion transporters that functions as a Cl- channel in parietal cells during acid secretion. We explored the role of SLC26A9 in colorectal cancer
Externí odkaz:
https://doaj.org/article/318e591c7c88469780130cb0150981ec
Autor:
Danxia Qiu, Yangcheng He, Yuyi Feng, Minhua Lin, Zekai Lin, Zhiyi Zhang, Ying Xiong, Zhiwen Hu, Suihong Ma, Hai Jin, Jianhua Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The tumor microenvironment is increasingly acknowledged as a critical contributor to cancer progression, mediating genetic and epigenetic alterations. Beyond diverse cellular interactions from the microenvironment, physicochemical factors such as tum
Externí odkaz:
https://doaj.org/article/836a86fc770f4c6ebb9f73d427326280