Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hai H Bui"'
Autor:
Firhan A Malik, Anja Meissner, Illya Semenkov, Steven Molinski, Stan Pasyk, Saumel Ahmadi, Hai H Bui, Christine E Bear, Darcy Lidington, Steffen-Sebastian Bolz
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130313 (2015)
The cystic fibrosis transmembrane conductance regulator (CFTR) attenuates sphingosine-1-phosphate (S1P) signaling in resistance arteries and has emerged as a prominent regulator of myogenic vasoconstriction. This investigation demonstrates that S1P i
Externí odkaz:
https://doaj.org/article/50f1f3716a3742b2861b9a3681b6dde8
Autor:
Nicholas B. Blackburn, Laura F. Michael, Peter J. Meikle, Juan M. Peralta, Marian Mosior, Scott McAhren, Hai H. Bui, Melissa A. Bellinger, Corey Giles, Satish Kumar, Ana C. Leandro, Marcio Almeida, Jacquelyn M. Weir, Michael C. Mahaney, Thomas D. Dyer, Laura Almasy, John L. VandeBerg, Sarah Williams-Blangero, David C. Glahn, Ravindranath Duggirala, Mark Kowala, John Blangero, Joanne E. Curran
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1630-1639 (2019)
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Externí odkaz:
https://doaj.org/article/7f7fa522a72f41e89dbc1874ed90eccd
Autor:
Frode Norheim, Thomas Bjellaas, Simon T. Hui, Karthickeyan Chella Krishnan, Jakleen Lee, Sonul Gupta, Calvin Pan, Yehudit Hasin-Brumshtein, Brian W. Parks, Daniel Y. Li, Hai H. Bui, Marian Mosier, Yuping Wu, Adriana Huertas-Vazquez, Stanley L. Hazen, Thomas E. Gundersen, Margarete Mehrabian, W.H.Wilson Tang, Andrea L. Hevener, Christian A. Drevon, Aldons J. Lusis
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 7, Pp 1164-1174 (2018)
Elevated hepatic ceramide levels have been implicated in both insulin resistance (IR) and hepatic steatosis. To understand the factors contributing to hepatic ceramide levels in mice of both sexes, we have quantitated ceramides in a reference populat
Externí odkaz:
https://doaj.org/article/f06455053a49487895841ef47b289931
Autor:
Jeremy Syrjanen, Michelle M. Mielke, Clifford R. Jack, Eseosa T. Ighodaro, Jonathan Graff-Radford, Prashanthi Vemuri, Hai H. Bui, David S. Knopman, Samantha M. Zuk, Ronald C. Petersen
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: High plasma ceramide levels and ratios are associated with poor outcomes in individuals with cardiovascular disease; less is known about their relation to cerebral small vessel disease. We examined whether high plasma ceramide levels or ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4679f6339c20209357a2acb40e3049
https://doi.org/10.1161/atvbaha.120.314796
https://doi.org/10.1161/atvbaha.120.314796
Autor:
Clinton E. Hagen, David S. Knopman, Danni Li, Mary M. Machulda, Michelle M. Mielke, Ronald C. Petersen, Hai H. Bui, Clifford R. Jack
Publikováno v:
Neurobiol Aging
It is unclear whether cerebrospinal fluid (CSF) phosphatidylcholines (PCs) are associated with neuroimaging measures of amyloid deposition and neurodegeneration (glucose metabolism, cortical thickness, and hippocampal volume), cognitive decline, or r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459daa0bdf2536144ae19dbb3a10afd4
https://doi.org/10.1016/j.neurobiolaging.2020.04.020
https://doi.org/10.1016/j.neurobiolaging.2020.04.020
Autor:
Ana C Leandro, Jacquelyn M. Weir, Joanne E. Curran, Marian Mosior, Juan M. Peralta, Satish Kumar, Michael C. Mahaney, Melissa A. Bellinger, Laura Almasy, John L. VandeBerg, Peter J. Meikle, David C. Glahn, Sarah Williams-Blangero, Nicholas B. Blackburn, Corey Giles, Ravindranath Duggirala, Marcio Almeida, John Blangero, Laura F. Michael, Mark C. Kowala, Thomas D. Dyer, Scott M. McAhren, Hai H. Bui
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1630-1639 (2019)
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd5703dd1c78a98f24f1e7acb2c2320
https://doi.org/10.1194/jlr.p094433
https://doi.org/10.1194/jlr.p094433
Autor:
Clinton E. Hagen, David S. Knopman, Michelle M. Mielke, Ashely R. Fett, Danni Li, Ronald C. Petersen, Clifford R. Jack, Prashanthi Vemuri, Mary M. Machulda, Hai H. Bui
Publikováno v:
Neurobiol Aging
Plasma phosphatidylcholines (PCs) have been examined in the context of Alzheimer's disease dementia. However, their association with longitudinal changes in amyloid deposition remains unknown. This study investigated the associations of 8 plasma PC l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccdc35eb63c369e9e2a5bd1aca4ddfe
https://doi.org/10.1016/j.neurobiolaging.2019.03.005
https://doi.org/10.1016/j.neurobiolaging.2019.03.005
Autor:
Gregory P. Donoho, Hai H. Bui, Diane M. Bodenmiller, Anthony S. Fischl, Ming Shang Kuo, Phillip E. Sanders
Publikováno v:
Analytical Biochemistry. 547:66-76
Phosphatidylinositol (3,4,5) trisphosphate (PIP3) is a biologically active membrane phospholipid that is essential for the growth and survival of all eukaryotic cells. We describe a new method that directly measures PIP3 and describe the HPLC separat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483a33e7f88cdabd5dbaeb3655ef5f8a
https://doi.org/10.1016/j.ab.2018.02.014
https://doi.org/10.1016/j.ab.2018.02.014
Autor:
Andrea L. Hevener, Aldons J. Lusis, Margarete Mehrabian, Simon T. Hui, Stanley L. Hazen, Thomas Bjellaas, Jakleen Lee, Yuping Wu, Karthickeyan Chella Krishnan, Christian A. Drevon, Marian Mosier, Thomas E. Gundersen, Yehudit Hasin-Brumshtein, Daniel Y. Li, Hai H. Bui, Brian W. Parks, W.H. Wilson Tang, Sonul Gupta, Adriana Huertas-Vazquez, Calvin Pan, Frode Norheim
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 7, Pp 1164-1174 (2018)
Journal of lipid research, vol 59, iss 7
Journal of lipid research, vol 59, iss 7
Elevated hepatic ceramide levels have been implicated in both insulin resistance (IR) and hepatic steatosis. To understand the factors contributing to hepatic ceramide levels in mice of both sexes, we have quantitated ceramides in a reference populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29d960a953fa0bcd5657503c1730e8d
http://www.sciencedirect.com/science/article/pii/S0022227520330753
http://www.sciencedirect.com/science/article/pii/S0022227520330753
Autor:
Adrian Vella, Hai H. Bui, Michelle M. Mielke, Sagar B Dugani, Luke R Christenson, Jeremiah A. Aakre
Publikováno v:
Diabetes Res Clin Pract
AIMS: The role of ceramides in the pathogenesis of type 2 diabetes mellitus (T2DM) is incompletely characterized. Given that ceramides represent therapeutic targets to disrupt the euglycemia-T2DM transition, we aimed to characterize their association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9512cb50d66182e2e23db01e94afbb8
https://doi.org/10.1016/j.diabres.2021.108991
https://doi.org/10.1016/j.diabres.2021.108991