Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hai B Tran"'
Autor:
Hai B Tran, Hubertus Jersmann, Tung Thanh Truong, Rhys Hamon, Eugene Roscioli, Miranda Ween, Melissa R Pitman, Stuart M Pitson, Greg Hodge, Paul N Reynolds, Sandra Hodge
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0179577 (2017)
We have previously established a link between impaired phagocytic capacity and deregulated S1P signaling in alveolar macrophages from COPD subjects. We hypothesize that this defect may include a disruption of epithelial-macrophage crosstalk via Spns2
Externí odkaz:
https://doaj.org/article/4866f6d998654c978d76ea4dc28e27ae
Autor:
Rhys Hamon, Claire C Homan, Hai B Tran, Violet R Mukaro, Susan E Lester, Eugene Roscioli, Mariea D Bosco, Chiara M Murgia, Margaret Leigh Ackland, Hubertus P Jersmann, Carol Lang, Peter D Zalewski, Sandra J Hodge
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110056 (2014)
Our previous studies have shown that nutritional zinc restriction exacerbates airway inflammation accompanied by an increase in caspase-3 activation and an accumulation of apoptotic epithelial cells in the bronchioles of the mice. Normally, apoptotic
Externí odkaz:
https://doaj.org/article/c81be4a2b8f74267b11d873cd6445881
Autor:
Hai B Tran, Jessica Ahern, Greg Hodge, Phillip Holt, Melinda M Dean, Paul N Reynolds, Sandra Hodge
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98571 (2014)
We have previously established that a defect in the ability of alveolar macrophages (AM) to phagocytose apoptotic cells (efferocytosis) and pathogens is a potential therapeutic target in COPD. We further showed that levels of mannose binding lectin (
Externí odkaz:
https://doaj.org/article/7deb6dbf33b543c78c6e7fb540c43161
Autor:
Hai B. Tran, Rhys Hamon, Hubertus Jersmann, Miranda P. Ween, Patrick Asare, Rainer Haberberger, Harshita Pant, Sandra J. Hodge
Publikováno v:
Journal of Inflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Introduction The role inflammasomes play in chronic obstructive pulmonary disease (COPD) is unclear. We hypothesised that the AIM2 inflammasome is activated in the airways of COPD patients, and in response to cigarette smoke. Methods Lung ti
Externí odkaz:
https://doaj.org/article/06034dcccc57403981b2900086cdefd2
Autor:
Miranda P. Ween, Jake B. White, Hai B. Tran, Violet Mukaro, Charles Jones, Matthew Macowan, Gregory Hodge, Paul J. Trim, Marten F. Snel, Sandra J. Hodge
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In chronic obstructive pulmonary disease (COPD) apoptotic bronchial epithelial cells are increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside bacterial phagocytosis. Epithelial cellular lipids, including thos
Externí odkaz:
https://doaj.org/article/78d884c250684b168035f4d76956f5ac
Autor:
Patrick F. Asare, Hai B. Tran, Plinio R. Hurtado, Griffith B. Perkins, Phan Nguyen, Hubertus Jersmann, Eugene Roscioli, Sandra Hodge
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 15 (2021)
Introduction/Rationale: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammat
Externí odkaz:
https://doaj.org/article/dbd46a76f302486c98c0d1a21e6b7af5
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Bushfires are increasing in frequency and severity worldwide. Bushfire smoke contains organic/inorganic compounds including aldehydes and acrolein. We described suppressive effects of tobacco smoke on the phagocytic capacity of airway macrop
Externí odkaz:
https://doaj.org/article/951fb943ffdc4a01ae08074cd1554b4b
Autor:
Greg Hodge, Hubertus Jersmann, Hai B Tran, Patrick F Asare, Minnu Jayapal, Paul N Reynolds, Mark Holmes, Sandra Hodge
Publikováno v:
Clin Exp Immunol
We previously showed increased steroid-resistant CD28null CD8+ senescent lymphocyte subsets in the peripheral blood from patients with chronic obstructive pulmonary disease (COPD). These cells expressed decreased levels of the glucocorticoid receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4ab8dddc11234dc6ff36736c24af04
https://doi.org/10.1093/cei/uxab037
https://doi.org/10.1093/cei/uxab037
Autor:
Hai B. Tran, Rachel Jakobczak, Adrian Abdo, Patrick Asare, Paul Reynolds, John Beltrame, Sandra Hodge, Peter Zalewski
Zinc homeostasis is vital to immune and other organ system functions, yet over a quarter of the world’s population is zinc deficient. Abnormal zinc transport or storage protein expression has been linked to diseases, such as cancer and chronic obst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3214973c6be9d4291ac5fcff860a5483
https://doi.org/10.21203/rs.3.rs-1539166/v1
https://doi.org/10.21203/rs.3.rs-1539166/v1
Autor:
Plinio R Hurtado, Patrick F. Asare, Hai B. Tran, Eugene Roscioli, Hubertus Jersmann, Phan Nguyen, Sandra Hodge, Griffith B. Perkins
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 15 (2021)
Therapeutic Advances in Respiratory Disease
Therapeutic Advances in Respiratory Disease
Introduction/Rationale: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9965c3735d3e7e13929118e3abb87a
https://doaj.org/article/dbd46a76f302486c98c0d1a21e6b7af5
https://doaj.org/article/dbd46a76f302486c98c0d1a21e6b7af5