Výsledky vyhledávání - "Hahnel Antje"

Akademický článek

Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients

Autor: Hahnel Antje, Wichmann Henri, Greither Thomas, Kappler Matthias, Würl Peter, Kotzsch Matthias, Taubert Helge, Vordermark Dirk, Bache Matthias

Publikováno v: BMC Cancer, Vol 12, Iss 1, p 131 (2012)

Abstract Background It is well known that osteopontin (OPN) plays an important role in tumor progression and that a high OPN expression level in several tumor entities correlates with poor prognosis in cancer patients. However, little is known about

Externí odkaz: https://doaj.org/article/9d2b663f6047495ebae5f621fa15a9f3

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Akademický článek

HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression

Autor: Bache Matthias, Kappler Matthias, Rot Swetlana, Wichmann Henri, Hahnel Antje, Kessler Jacqueline, Vordermark Dirk

Publikováno v: BMC Cancer, Vol 10, Iss 1, p 605 (2010)

Abstract Background Hypoxia induces activation of the HIF-1 pathway and is an essential characteristic of malignant gliomas. Hypoxia has been linked to tumor progression, therapy resistance and poor prognosis. However, little is known about the impac

Externí odkaz: https://doaj.org/article/010d7aff3cad4ea2b93f61a2c8cf6a9f

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Akademický článek

Effects of osteopontin inhibition on radiosensitivityof MDA-MB-231 breast cancer cells

Autor: Hahnel Antje, Wichmann Henri, Kappler Matthias, Kotzsch Matthias, Vordermark Dirk, Taubert Helge, Bache Matthias

Publikováno v: Radiation Oncology, Vol 5, Iss 1, p 82 (2010)

Abstract Background Osteopontin (OPN) is a secreted glycophosphoprotein that is overexpressed in various tumors, and high levels of OPN have been associated with poor prognosis of cancer patients. In patients with head and neck cancer, high OPN plasm

Externí odkaz: https://doaj.org/article/98bcac910402422c8d3e77306eb33119

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Akademický článek

Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients

Autor: Kotzsch Matthias, Said Harun M, Greither Thomas, Hahnel Antje, Rot Swetlana, Wichmann Henri, Kappler Matthias, Bache Matthias, Würl Peter, Taubert Helge, Vordermark Dirk

Publikováno v: BMC Cancer, Vol 10, Iss 1, p 132 (2010)

Abstract Background Osteopontin (OPN) overexpression is correlated with a poor prognosis for tumor patients. However, only a few studies investigated the prognostic impact of expression of OPN in soft tissue sarcomas (STS) yet. Methods This study is

Externí odkaz: https://doaj.org/article/4ad52adf241644abb108494e72028b93

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