Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hagit T Porath"'
Autor:
Ilana Buchumenski, Osnat Bartok, Reut Ashwal-Fluss, Varun Pandey, Hagit T Porath, Erez Y Levanon, Sebastian Kadener
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006931 (2017)
In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperature adaptation in Drosophila. Although there is a
Externí odkaz:
https://doaj.org/article/eccc81e6702c4685a8336bb5042662f9
Autor:
Adi Shamay-Ramot, Khen Khermesh, Hagit T Porath, Michal Barak, Yishay Pinto, Chaim Wachtel, Alona Zilberberg, Tali Lerer-Goldshtein, Sol Efroni, Erez Y Levanon, Lior Appelbaum
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005702 (2015)
Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (F
Externí odkaz:
https://doaj.org/article/a926f0f2ecef4001bfe38aa8dd4fe5dc
Autor:
Michal Barak, Hagit T. Porath, Gilad Finkelstein, Binyamin A. Knisbacher, Ilana Buchumenski, Shalom Hillel Roth, Erez Y. Levanon, Eli Eisenberg
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Mobile elements comprise a large fraction of metazoan genomes. Accumulation of mobile elements is bound to produce multiple putative double-stranded RNA (dsRNA) structures within the transcriptome. These endogenous dsRNA structure
Externí odkaz:
https://doaj.org/article/80a92672d7614a75a5805c2a67aea2a3
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101983- (2021)
Summary: Social insects exhibit extensive phenotypic diversities among the genetically similar individuals, suggesting a role for the epigenetic regulations beyond the genome level. The ADAR-mediated adenosine-to-inosine (A-to-I) RNA editing, an evol
Externí odkaz:
https://doaj.org/article/38c5679ee0fc42e58cf31215d5169320
Autor:
Esther Hazan, Eli Eisenberg, Hagai Y. Shpigler, Yehuda Ben-Shahar, Guy Bloch, Mark Band, Hagit T. Porath, Mira Cohen, Erez Y. Levanon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Colonies of the bumblebee Bombus terrestris are characterized by wide phenotypic variability among genetically similar full-sister workers, suggesting a major role for epigenetic processes. Here, we report a high level of ADAR-mediated RNA editing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14047f860e0b80302f54e4aae4725221
https://doaj.org/article/87a1442fe9154b3c97e80db85f7ebad6
https://doaj.org/article/87a1442fe9154b3c97e80db85f7ebad6
Publikováno v:
iScience
iScience, Vol 24, Iss 1, Pp 101983-(2021)
iScience, Vol 24, Iss 1, Pp 101983-(2021)
Summary Social insects exhibit extensive phenotypic diversities among the genetically similar individuals, suggesting a role for the epigenetic regulations beyond the genome level. The ADAR-mediated adenosine-to-inosine (A-to-I) RNA editing, an evolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b75c876aa978243bb32d4cac75983f6
https://pubmed.ncbi.nlm.nih.gov/33458624
https://pubmed.ncbi.nlm.nih.gov/33458624
Autor:
Cydney Rios, Hagit T. Porath, Timothy Daley, Max A. Seibold, Serghei Mangul, Andrew D. Smith, Prescott G. Woodruff, Kevin Hsieh, Jose Rodriguez Santana, Celeste Eng, Harry Taegyun Yang, Nicolas Strauli, Agata Wesolowska-Andersen, Esteban G. Burchard, Eleazar Eskin, Sagiv Shifman, Linus Chen, Stephanie A. Christenson, Franziska Gruhl, Erez Y. Levanon, Roberto Spreafico, Roel A. Ophoff, Ryan D. Hernandez, Noah Zaitlen
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-12 (2018)
Genome biology, vol 19, iss 1
Genome Biology, vol. 19, no. 1, pp. 36
Genome Biology
Genome biology, vol 19, iss 1
Genome Biology, vol. 19, no. 1, pp. 36
Genome Biology
High-throughput RNA-sequencing (RNA-seq) technologies provide an unprecedented opportunity to explore the individual transcriptome. Unmapped reads are a large and often overlooked output of standard RNA-seq analyses. Here, we present Read Origin Prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21c064ff6dc859f0bfc3f29617197a4
http://link.springer.com/article/10.1186/s13059-018-1403-7
http://link.springer.com/article/10.1186/s13059-018-1403-7
Autor:
G. Rechavi, Oz Solomon, Yaniv Lerenthal, Ron Unger, Victoria Marcu-Malina, Ayelet Di Segni, Hagit T. Porath, Erez Y. Levanon, Karen Cesarkas, Nitzan Kol, Ninette Amariglio, Orel Mizrahi, Eran Eyal, Noam Stern-Ginossar, Efrat Glick-Saar, Itamar Goldstein, Sarit Farage-Barhom
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10a55c86cb86840b32c14b3bb151ed
http://link.springer.com/article/10.1038/s41467-017-01458-8
http://link.springer.com/article/10.1038/s41467-017-01458-8
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-12 (2017)
Genome Biology
Genome Biology
Background Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans. Technical requirements have limited sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2370203762f3012f2c2e6464b984c69d
https://doi.org/10.1186/s13059-017-1315-y
https://doi.org/10.1186/s13059-017-1315-y
Autor:
Oren Levy, Amos A Schaffer, Joshua J. C. Rosenthal, Eli Eisenberg, Shahar Alon, Hagit T. Porath, Erez Y. Levanon, Paulina Kaniewska
Publikováno v:
Molecular Biology and Evolution
The highly conserved ADAR enzymes, found in all multicellular metazoans, catalyze the editing of mRNA transcripts by the deamination of adenosines to inosines. This type of editing has two general outcomes: site specific editing, which frequently lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491048e2f60076194a52c499f9d725bf
https://pubmed.ncbi.nlm.nih.gov/28453786
https://pubmed.ncbi.nlm.nih.gov/28453786