Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Hagir B Suliman"'
Autor:
Raquel R Bartz, Ping Fu, Hagir B Suliman, Stephen D Crowley, Nancy Chou MacGarvey, Karen Welty-Wolf, Claude A Piantadosi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100912 (2014)
Acute kidney injury (AKI) contributes to the high morbidity and mortality of multi-system organ failure in sepsis. However, recovery of renal function after sepsis-induced AKI suggests active repair of energy-producing pathways. Here, we tested the h
Externí odkaz:
https://doaj.org/article/e5b6e08fc4fb438fbad60ea57fd16221
Autor:
Timothy E Sweeney, Hagir B Suliman, John W Hollingsworth, Karen E Welty-Wolf, Claude A Piantadosi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25249 (2011)
Activation of the host antibacterial defenses by the toll-like receptors (TLR) also selectively activates energy-sensing and metabolic pathways, but the mechanisms are poorly understood. This includes the metabolic and mitochondrial biogenesis master
Externí odkaz:
https://doaj.org/article/81c62789aeda430ab7335cd319989d47
Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11606 (2010)
The PGC family of transcriptional co-activators (PGC-1alpha [Ppargc1a], PGC-1beta [Ppargc1b], and PRC [Pprc]) coordinates the upregulation of mitochondrial biogenesis, and Ppargc1a is known to be activated in response to mitochondrial damage in sepsi
Externí odkaz:
https://doaj.org/article/17fde4beaaed4030bb7366faf735b245
Autor:
Ivan T. Demchenko, Hagir B. Suliman, Sergey Y. Zhilyaey, Olga S. Alekseeva, Tatyana F. Platonova, Matthew S. Makowski, Claude A. Piantadosi, Heath G. Gasier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
Oxygen breathing at elevated partial pressures (PO2’s) at or more than 3 atmospheres absolute (ATA) causes a reduction in brain γ-aminobutyric acid (GABA) levels that impacts the development of central nervous system oxygen toxicity (CNS-OT). Drug
Externí odkaz:
https://doaj.org/article/eef69bbadec3422d86f5bb6d59657ba8
Autor:
Miguel Alvarez Villela, Sophia A. Dunworth, Bryan D. Kraft, Nicole P. Harlan, Michael J. Natoli, Hagir B. Suliman, Richard E. Moon
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Hyperbaric Oxygen (HBO2) has been proposed as a pre-conditioning method to enhance exercise performance. Most prior studies testing this effect have been limited by inadequate methodologies. Its potential efficacy and mechanism of action remain unkno
Externí odkaz:
https://doaj.org/article/36883fac98c441948e0014b29f1b851f
Autor:
Hagir B. Suliman, Zachary Healy, Fabio Zobi, Bryan D. Kraft, Karen Welty-Wolf, Joshua Smith, Christina Barkauskas, Claude A. Piantadosi
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103535- (2022)
Summary: The preclinical model of bleomycin-induced lung fibrosis is useful to study mechanisms related to human pulmonary fibrosis. Using BLM in mice, we find low HO-1 expression. Although a unique Rhenium-CO-releasing molecule (ReCORM) up-regulates
Externí odkaz:
https://doaj.org/article/59b5ccf9de1247a680363d09e5bf4f49
Autor:
Zachary R. Healy, Joshua D. Smith, Hagir B. Suliman, Bryan Kraft, Fabio Zobi, Christina Barkaskas, Karen E. Welty-Wolf, Claude A. Piantadosi
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103535-(2022)
iScience
iScience
Summary The preclinical model of bleomycin-induced lung fibrosis is useful to study mechanisms related to human pulmonary fibrosis. Using BLM in mice, we find low HO-1 expression. Although a unique Rhenium-CO-releasing molecule (ReCORM) up-regulates
Publikováno v:
Exercise and sport sciences reviews. 50(1)
Inducible heme oxygenase (HO)-1 catalyzes the breakdown of heme to biliverdin, iron, and carbon monoxide (CO). CO binds to cytochrome c oxidase and alters mitochondrial redox balance and coordinately regulates mitochondrial quality control (MQC) duri
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Oxidative and nitrosative stress are primary contributors to the loss of myocardial tissue in insults ranging from ischemia/reperfusion injury from coronary artery disease and heart transplantation to sepsis-induced myocardial dysfunction and drug-in
Externí odkaz:
https://doaj.org/article/d693367eeee74c56a6e70ee5d7b566f0
Autor:
Qing Ma, Benjamin T. Morris, Steven D. Crowley, Jamie R. Privratsky, Jiafa Ren, Zhiquan Zhang, Luis Ulloa, Hagir B. Suliman
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Background:Acute kidney injury (AKI) is one of the most common organ failures following surgery. We have developed a tripeptide mimetic (ANXA1sp) of the parent annexin A1 molecule that shows promise as an organ protectant limiting cellular stress; ho