Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hagen M. Gegner"'
Autor:
Hagen M. Gegner, Thomas Naake, Aurélien Dugourd, Torsten Müller, Felix Czernilofsky, Georg Kliewer, Evelyn Jäger, Barbara Helm, Nina Kunze-Rohrbach, Ursula Klingmüller, Carsten Hopf, Carsten Müller-Tidow, Sascha Dietrich, Julio Saez-Rodriguez, Wolfgang Huber, Rüdiger Hell, Gernot Poschet, Jeroen Krijgsveld
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Metabolomic and proteomic analyses of human plasma and serum samples harbor the power to advance our understanding of disease biology. Pre-analytical factors may contribute to variability and bias in the detection of analytes, especially when multipl
Externí odkaz:
https://doaj.org/article/13786df52f9646db9487239e968656a6
Autor:
Carolin Andresen, Tobias Boch, Hagen M. Gegner, Nils Mechtel, Andreas Narr, Emrullah Birgin, Erik Rasbach, Nuh Rahbari, Andreas Trumpp, Gernot Poschet, Daniel Hübschmann
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Analyses of metabolic compounds inside cells or tissues provide high information content since they represent the endpoint of biological information flow and are a snapshot of the integration of many regulatory processes. However, quantification of t
Externí odkaz:
https://doaj.org/article/62facc52ca3149f7aad06d434be45a5f
Autor:
Hagen M. Gegner, Nils Mechtel, Elena Heidenreich, Angela Wirth, Fabiola Garcia Cortizo, Katrin Bennewitz, Thomas Fleming, Carolin Andresen, Marc Freichel, Aurelio A. Teleman, Jens Kroll, Rüdiger Hell, Gernot Poschet
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Metabolic profiling harbors the potential to better understand various disease entities such as cancer, diabetes, Alzheimer’s, Parkinson’s disease or COVID-19. To better understand such diseases and their intricate metabolic pathways in human stu
Externí odkaz:
https://doaj.org/article/1071d247f0c043dca734c40fef308b52
Autor:
Soumya R. Mohapatra, Ahmed Sadik, Suraj Sharma, Gernot Poschet, Hagen M. Gegner, Tobias V. Lanz, Philippe Lucarelli, Ursula Klingmüller, Michael Platten, Ines Heiland, Christiane A. Opitz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The liver is the central hub for processing and maintaining homeostatic levels of dietary nutrients especially essential amino acids such as tryptophan (Trp). Trp is required not only to sustain protein synthesis but also as a precursor for the produ
Externí odkaz:
https://doaj.org/article/2e66a4fdaf604518ae00622bd1b6f151
Publikováno v:
Frontiers in Marine Science, Vol 7 (2020)
Coral bleaching, i.e., the loss of photosynthetic algal endosymbionts, caused by ocean warming is now among the main factors driving global reef decline, making the elucidation of factors that contribute to thermotolerance important. Recent studies i
Externí odkaz:
https://doaj.org/article/da027b507c69471c850b7018e1a9a657
Autor:
Hagen M. Gegner, Nils Rädecker, Michael Ochsenkühn, Marcelle M. Barreto, Maren Ziegler, Jessica Reichert, Patrick Schubert, Thomas Wilke, Christian R. Voolstra
Publikováno v:
Biology Open, Vol 8, Iss 12 (2019)
Coral reefs are in global decline mainly due to increasing sea surface temperatures triggering coral bleaching. Recently, high salinity has been linked to increased thermotolerance and decreased bleaching in the sea anemone coral model Aiptasia. Howe
Externí odkaz:
https://doaj.org/article/34290ed0a9af46c1b6868bf5ef535163
Autor:
Hagen M. Gegner, Maren Ziegler, Nils Rädecker, Carol Buitrago-López, Manuel Aranda, Christian R. Voolstra
Publikováno v:
Biology Open, Vol 6, Iss 12, Pp 1943-1948 (2017)
The endosymbiosis between dinoflagellate algae of the genus Symbiodinium and stony corals provides the foundation of coral reef ecosystems. Coral bleaching, the expulsion of endosymbionts from the coral host tissue as a consequence of heat or light s
Externí odkaz:
https://doaj.org/article/760398c7904146febd9bdbedf90e7c7f
Autor:
Hagen M. Gegner, Rúben M. Costa
Publikováno v:
Frontiers for Young Minds. 10
You may have heard that coral reefs are overheating and are vanishing from our planet. Although this is certainly the case, the news is not all grim and gloomy! Every so often, surprising experiments show us that there is still hope for corals and mu
Autor:
Philipp C. Münch, Lukas Bunse, Camila Fernández-Zapata, Josef Priller, Oliver Schnell, Sabine Heiland, Jürgen Beck, Edward W. Green, Chotima Böttcher, Denis Abu-Sammour, Francisco J. Quintana, Roman Sankowski, Felix Sahm, Carina Ramallo Guevara, Wolfgang Wick, Khwab Sanghvi, Tobias Kessler, Tim Trobisch, Frederik Cichon, Carsten Hopf, Lucas Schirmer, Michael Platten, Dieter Henrik Heiland, Miriam Ratliff, Anna von Landenberg, Theresa Bunse, Jana K. Sonner, Daniel Schrimpf, Mirco Friedrich, Marco Prinz, Hagen M. Gegner, Ilona Gutcher, Stefan Pusch, Michael Kilian, Gernot Poschet, Katrin Aslan, Markus Hahn, Andreas von Deimling
Publikováno v:
Nature cancer 2(7), 723-740 (2021). doi:10.1038/s43018-021-00201-z
The dynamics and phenotypes of intratumoral myeloid cells during tumor progression are poorly understood. Here we define myeloid cellular states in gliomas by longitudinal single-cell profiling and demonstrate their strict control by the tumor genoty
Autor:
Carol Buitrago-López, Hagen M. Gegner, Kiruthiga Mariappan, Christian R. Voolstra, Anny Cárdenas
Publikováno v:
Genome Biology and Evolution
Climate change and ocean warming threaten the persistence of corals worldwide. Genomic resources are critical to study the evolutionary trajectory, adaptive potential, and genetic distinctiveness of coral species. Here, we provide a reference genome