Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Hagberg, Niklas"'
Autor:
Gaziano, Liam, Giambartolomei, Claudia, Pereira, Alexandre C, Gaulton, Anna, Posner, Daniel C, Swanson, Sonja A, Ho, Yuk-Lam, Iyengar, Sudha K, Kosik, Nicole M, Vujkovic, Marijana, Gagnon, David R, Bento, A Patrícia, Barrio-Hernandez, Inigo, Rönnblom, Lars, Hagberg, Niklas, Lundtoft, Christian, Langenberg, Claudia, Pietzner, Maik, Valentine, Dennis, Gustincich, Stefano, Tartaglia, Gian Gaetano, Allara, Elias, Surendran, Praveen, Burgess, Stephen, Zhao, Jing Hua, Peters, James E, Prins, Bram P, Angelantonio, Emanuele Di, Devineni, Poornima, Shi, Yunling, Lynch, Kristine E, DuVall, Scott L, Garcon, Helene, Thomann, Lauren O, Zhou, Jin J, Gorman, Bryan R, Huffman, Jennifer E, O'Donnell, Christopher J, Tsao, Philip S, Beckham, Jean C, Pyarajan, Saiju, Muralidhar, Sumitra, Huang, Grant D, Ramoni, Rachel, Beltrao, Pedro, Danesh, John, Hung, Adriana M, Chang, Kyong-Mi, Sun, Yan V, Joseph, Jacob, Leach, Andrew R, Edwards, Todd L, Cho, Kelly, Gaziano, J Michael, Butterworth, Adam S, Casas, Juan P, VA Million Veteran Program COVID-19 Science Initiative
Publikováno v:
Nature Medicine, 27(4), 668-676. Nature Publishing Group
Nature Medicine
Nature Medicine
Drug repurposing provides a rapid approach to meet the urgent need for therapeutics to address COVID-19. To identify therapeutic targets relevant to COVID-19, we conducted Mendelian randomization analyses, deriving genetic instruments based on transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5653dcf0ca1ae45913aa18266221486
https://doi.org/10.1038/s41591-021-01310-z
https://doi.org/10.1038/s41591-021-01310-z
Autor:
Hagberg, Niklas1 (AUTHOR) niklas.hagberg@medsci.uu.se, Lundtoft, Christian1 (AUTHOR), Rönnblom, Lars1 (AUTHOR)
Publikováno v:
Scandinavian Journal of Immunology. Oct2020, Vol. 92 Issue 4, p1-11. 11p.
Akademický článek
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Akademický článek
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Additional file 5: Figure S3. Type I IFN production is induced in pDCs and pDC-NK or pDC-B cell co-cultures stimulated with RNA-IC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea134be0f702bb645e08914d479266f8
Additional file 2: Methods. Gene expression microarray. Single-cell RNA expression profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7e13c992f4ab6bc33b7375e4a8cdbe
Additional file 3: Table S1. Clinical characteristics of SLE patients and their treatment at the time of blood sampling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803cc69400545e7506f5707b17cfba93
Additional file 8: Table S3. Differentially expressed genes (DEGs) in RNA-IC stimulated pDCs overexpressed in cluster “0” vs cluster “1” following unsupervised clustering of the 2000 most variable genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a5e99b0fa564d5c87eb112093ba327
Additional file 4: Figure S2. Type III IFN production is induced in pDCs and pDC-B cell co-cultures stimulated with RNA containing immune complexes (RNA-IC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e77179b8857187eb5b312297c2f3b08
Additional file 9: Figure S5. Interferon (IFN)-α production is triggered by RNA containing immune complexes (RNA-IC) in immune cells from systemic lupus erythematosus patients (SLE) patients and healthy controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1001f4e4879548f38fe2a3f3595f29c1