Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hafsa Munir"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109546- (2024)
Summary: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous immune population with diverse immunosuppressive functions in solid tumors. Here, we explored the role of the tumor microenvironment in regulating MDSC differentiation and immunosu
Externí odkaz:
https://doaj.org/article/3cd85a25ea7a48bab9c5195f81deb7d5
Autor:
Hafsa Munir, James O. Jones, Tobias Janowitz, Markus Hoffmann, Maximilien Euler, Carla P. Martins, Sarah J. Welsh, Jacqueline D. Shields
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The tumor microenvironment is composed of many cell types that crosstalk to modulate local immunity. Here the authors show that Amyloid β proteins from cancer-associated fibroblasts (CAF) induce neutrophil extracellular trap (NET) production by neut
Externí odkaz:
https://doaj.org/article/2556fc9e34b0446f9be86ba29dd43111
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Tumours employ a variety of strategies to induce immune suppression. Here the authors show that cancer-associated fibroblasts process and cross-present tumour-antigens to T-cells resulting in antigen-specific T cell death and dysfunction via upregula
Externí odkaz:
https://doaj.org/article/b48c058284114b0fae05f95b3bfc6c35
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155161 (2016)
Mesenchymal stromal cells (MSC) are tissue-resident stromal cells capable of modulating immune responses, including leukocyte recruitment by endothelial cells (EC). However, the comparative potency of MSC from different sources in suppressing recruit
Externí odkaz:
https://doaj.org/article/93f77d9aa85d4d10ba9c24e1a6d16f03
Autor:
Hafsa Munir, Wan Safwani Wan Kamarul Zaman, Vieralynda Vitus, Norita Mohd Zain, Fazlina Nordin, Mh Busra Fauzi
Publikováno v:
Emergent Materials. 6:405-424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfee3cddfd9294b1ae03f053f4a0e15c
https://doi.org/10.1007/s42247-023-00459-2
https://doi.org/10.1007/s42247-023-00459-2
Publikováno v:
Advanced Drug Delivery Reviews. :75-89
Recent advances have identified a growing array of roles played by lymphatics in the tumor microenvironment, from providing a route of metastasis to immune modulation. The tumor microenvironment represents an exceptionally complex, dynamic niche comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faac754474c66b83d6a65726d034c3ee
https://doi.org/10.1016/j.addr.2020.08.001
https://doi.org/10.1016/j.addr.2020.08.001
Autor:
Theresa T. Lu, Hafsa Munir
Publikováno v:
The Journal of experimental medicine. 218(9)
In this issue of JEM, Podstawka et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210409) show that B cells can limit neutrophil responses within the lung microvasculature by marginating and acting on marginated neutrophils. This study provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de301abb964c5a49567a21ec5f79ffc0
https://pubmed.ncbi.nlm.nih.gov/34313733
https://pubmed.ncbi.nlm.nih.gov/34313733
Autor:
Helen M. McGettrick, Lewis S. C. Ward, Mohammed Alassiri, Asma Alanazi, Gerard B. Nash, Hafsa Munir
Publikováno v:
Biorheology. 56:15-30
Background Mesenchymal stem cells (MSC) are used in therapy, often by injection into the blood. Objective We aimed to compare the adhesive and migratory properties of MSC from umbilical cords (UCMSC), bone marrow (BMMSC) or trabecular bone (TBMSC), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6d13870b5091093985cca357d5dfbb
https://doi.org/10.3233/bir-180185
https://doi.org/10.3233/bir-180185
Autor:
Maximilien Euler, Sarah J. Welsh, James O. Jones, Carla P. Martins, Tobias Janowitz, Hafsa Munir, Jacqueline D. Shields, Markus H. Hoffmann
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Tumors consist of cancer cells and a network of non-cancerous stroma. Cancer-associated fibroblasts (CAF) are known to support tumorigenesis, and are emerging as immune modulators. Neutrophils release histone-bound nuclear DNA and cytotoxic granules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a40f8072dc37af484a1d38110b36fd
https://www.repository.cam.ac.uk/handle/1810/316869
https://www.repository.cam.ac.uk/handle/1810/316869
Autor:
James O. Jones, Tobias Janowitz, Carla P. Martins, Jacqueline D. Shields, Hafsa Munir, Sarah J. Welsh
Tumors are comprised of cancer cells and a network of non-cancerous stromal cells. Cancer-associated fibroblasts (CAFs) are well known to support tumorigenesis and are emerging as immune modulators. While many leukocyte populations are well studied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f965d09197a0d2304192fcf64315d5d4