Výsledky vyhledávání - "Hafsa Al-Azzawi"

Enhancing chemosensitivity of wild-type and drug-resistant MDA-MB-231 triple-negative breast cancer cell line to doxorubicin by silencing of STAT 3, Notch-1, and β-catenin genes

Autor: Dana A. Alqudah, Hafsa Al-Azzawi, Lobna Gharaibeh, Mamoun Souleiman, Abdalla Awidi, Arwa Alkaraki, Walhan Alshaer, Duaa Abuarqoub, Suha Wehaibi, Hadil Zureigat

Publikováno v: Breast Cancer. 27:989-998

The absence of receptors in triple-negative breast cancer limits therapeutic choices utilized in clinical management of the disease. Doxorubicin is an important member of therapeutic regimens that is hindered by emergence of resistance. The current w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520eda14aebf6b1c35667fd122f5d55c
https://doi.org/10.1007/s12282-020-01098-9

Zobrazit plný text záznamu

Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion

Autor: Rand Zaza, Abeer Al Bawab, Walhan Alshaer, Duaa Abuarqoub, Said I. Ismail, Hamdi Nsairat, Malak I. Qadri, Ismail S. Mahmoud, Hafsa Al-Azzawi, Fadwa Odeh, Abdalla Awidi

Publikováno v: RSC Advances. 10:36219-36229

A new combination strategy of an active loading and active targeting approach was applied in this work. The liposomes actively loaded with Curcumin (CRM) (LipCRM) were decorated with cholesterol tagged-anti-nucleolin AS1411 aptamer (NCL) via a new po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299d4619476b5d7af2c6ae7dcbadde59
https://doi.org/10.1039/d0ra07325c

Zobrazit plný text záznamu

Multifunctional nanoparticles recruiting hyaluronic acid ligand and polyplexes containing low molecular weight protamine and ATP-Sensitive DNA motif for doxorubicin delivery

Autor: Hafsa Al-Azzawi, Walhan Alshaer, Ezaldeen Esawi, Zainab Lafi, Duaa Abuarqoub, Rand Zaza, Manar Zraikat, Abdelkader Battah, Abdalla Awidi

Publikováno v: Journal of Drug Delivery Science and Technology. 69:103169

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3de416abc036cf44d5628cd1cd6c1d80
https://doi.org/10.1016/j.jddst.2022.103169

Zobrazit plný text záznamu

Fabrication of aptamer-guided siRNA loaded lipopolyplexes for gene silencing of notch 1 in MDA-mb-231 triple negative breast cancer cell line

Autor: Lobna Gharaibeh, Dana A. Alqudah, Suha Wehaibi, Yasser Bustanji, Abdalla Awidi, Hafsa Al-Azzawi, Abdulfattah Al-Kadash, Rula Al Buqain, Walhan Alshaer

Publikováno v: Journal of Drug Delivery Science and Technology. 65:102733

Triple negative breast cancer is an aggressive type of cancer with limited therapeutic options. Aptamer-functionalized liposomes to deliver short interference RNAs (siRNAs) offer a promising therapeutic option. The current study aimed at preparing an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0206506fd5499e918e1811f13dca0d0
https://doi.org/10.1016/j.jddst.2021.102733

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání