Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hafez F. Hafez"'
Autor:
Mariam A. Fouad, Mohamed M. Sayed-Ahmed, Etimad A. Huwait, Hafez F. Hafez, Abdel-Moneim M. Osman
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Hormonal receptor positive (HR+) breast cancer is the most commonly diagnosed molecular subtype of breast cancer; which showed good response to doxorubicin (DOX)-based chemotherapy. Eugenol (EUG) and astaxanthin (AST) are natural
Externí odkaz:
https://doaj.org/article/a77541fd0b33425db5f672a65c19dfa8
Autor:
Mariam A. Fouad, Salem E. Salem, Marwa M. Hussein, Abdel Rahman N. Zekri, Hafez F. Hafez, Eman D. El Desouky, Samia A. Shouman
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Global DNA methylation has an impact in cancer pathogenesis and progression. This study aimed at investigating the impact of global DNA methylation in treatment outcome of Colorectal Cancer (CRC).Patients and Methods: Global DNA methylati
Externí odkaz:
https://doaj.org/article/3e764ce1cd3b4018925828e8db1a82ff
Autor:
Samia A. Shouman, Doaa M Badr, Marwa M. Hussien, Salem E. Salem, Mariam A. Fouad, Hafez F. Hafez, Abdel-Rahman N. Zekri
Publikováno v:
Epigenetics Insights, Vol 14 (2021)
Epigenetics Insights
Epigenetics Insights
Aims: This study investigated the impact of promoter methylation of flouropyrimidine (FP) metabolizing and cyclooxygenase 2 (COX2) genes on their mRNA expression and on the clinical outcome of colorectal cancer (CRC) patients. Methods: Methylation sp
Autor:
Etimad A. Huwait, Hafez F. Hafez, Mohamed M. Sayed-Ahmed, Mariam A. Fouad, Abdel-Moneim M. Osman
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-15 (2021)
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-15 (2021)
Background Hormonal receptor positive (HR+) breast cancer is the most commonly diagnosed molecular subtype of breast cancer; which showed good response to doxorubicin (DOX)-based chemotherapy. Eugenol (EUG) and astaxanthin (AST) are natural compounds
Fluoropyrimdine therapy induced alterations in interleukins expression in colorectal cancer patients
Autor:
Abdel-Rahman N. Zekri, Doaa M Badr, Mahmoud M. Kamel, Marwa M. Hussein, Samia A. Shouman, Salem E. Salem, Hafez F. Hafez, Mariam A. Fouad, Afaf S. Osman
Publikováno v:
International Journal of Immunopathology and Pharmacology
This study monitored the changes in the expression of inflammatory IL-6 and IL-1β during the treatment period of Fluoropyrimidine (FP) based therapy. RNA was extracted from the peripheral blood of 102 CRC patients before treatment with FP therapy, a
The Combination ofα-Tocopheryl Succinate and Sodium Selenite on Breast Cancer: A Merit or a Demerit?
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
α-Tocopheryl succinate (α-TOS), a mitochondria-targeting agent, induces apoptosis in malignant cells in vitro and in vivo. Selenite is a nutritional supplement that has been shown to stimulate apoptosis in cancer cells. This study was designed to i
Autor:
Eman D. El Desouky, Samia A. Shouman, Marwa M. Hussein, Salem E. Salem, Hafez F. Hafez, Abdel-Rahman N. Zekri, Mariam A. Fouad
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology
Frontiers in Pharmacology
Background: Global DNA methylation has an impact in cancer pathogenesis and progression. This study aimed at investigating the impact of global DNA methylation in treatment outcome of Colorectal Cancer (CRC).Patients and Methods: Global DNA methylati
Publikováno v:
Biomedicine & Aging Pathology. 4:265-272
The present study was carried out to investigate the antioxidant activity and the protective effects of the aqueous leaf extract of Moringa oleifera (MO) on α-radiation-induced toxicity in cardiac and pulmonary tissues in rats. Rats were administere
Autor:
Hanan Fouad, Fatma M. Taha, Abdulrahman L. Al-Malki, Amira Hassouna, Hafez F. Hafez, Mohamed Abd El Aziz, Mohamed Farid El-Asmer, Ameen M Rezq, Hanan H. Ahmed, Taha A. Kumosani
Publikováno v:
BioFactors. 40:132-137
Novel water-soluble curcumin derivatives have been developed to overcome low in vivo bioavailability of curcumin. The aim of this work is to assess the potential utility of certain downstream targets as bioavailability indicators of systemic activity
Autor:
Hafez F. Hafez, Heba Hosny Mansour
Publikováno v:
Ecotoxicology and Environmental Safety. 80:14-19
The aim of this study was to investigate the protective effect of root extract of Withania somnifera (WS) against gamma-irradiation-induced oxidative stress and DNA damage in hepatic tissue after whole body gamma-irradiation. Fourty male albino rats