Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Haeng-Ran Seo"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Hepatocellular carcinoma (HCC) is a complex disease associated with a plethora of environmental and genetic/hereditary causative risk factors, more so than other oncological indications. Additionally, patients with HCC exhibit fibrosis, cirr
Externí odkaz:
https://doaj.org/article/5443934da09d4422a4b5778ad62c2f1b
Autor:
Su-Yeon Lee, Sanghwa Kim, Inhee Choi, Yeonhwa Song, Namjeong Kim, Hyung Chul Ryu, Jee Woong Lim, Hyo Jin Kang, Jason Kim, Haeng Ran Seo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-11 (2022)
Abstract 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Although 11βHSD1 has been implicated in numerous metabolic syndromes, such as o
Externí odkaz:
https://doaj.org/article/36fb516f0e0e4b41a7a98bd1d3942c9d
Autor:
Yeonhwa Song, Sanghwa Kim, Jinyeong Heo, David Shum, Su-Yeon Lee, Minji Lee, A-Ram Kim, Haeng Ran Seo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract A chronic, local inflammatory milieu can cause tissue fibrosis that results in epithelial-to-mesenchymal transition (EMT), endothelial-to-mesenchymal transition (EndMT), increased abundance of fibroblasts, and further acceleration of fibrosi
Externí odkaz:
https://doaj.org/article/60f1bcc2f01e4486943eb23c58717e36
Autor:
Sanghwa Kim, Minji Lee, Yeonhwa Song, Su-Yeon Lee, Inhee Choi, I-Seul Park, Jiho Kim, Jin-sun Kim, Kang mo Kim, Haeng Ran Seo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant cancers worldwide, and liver cancer has increased in mortality due to liver cancer because it was detected at an advanced stages in patients with liver dysfunction
Externí odkaz:
https://doaj.org/article/e5f2ab7eaab24620b6335ddbce5e7714
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Chemotherapy used for patients with unresectable lung tumors remains largely palliative due to chemoresistance, which may be due to tumor heterogeneity. Recently, multiple studies on the crosstalk between lung cancer cells and the
Externí odkaz:
https://doaj.org/article/b3d58cbb517e4ff4a0b94e7b506767a2
Autor:
Ayoub Lafnoune, Su-Yeon Lee, Jin-Yeong Heo, Khadija Daoudi, Bouchra Darkaoui, Salma Chakir, Rachida Cadi, Khadija Mounaji, David Shum, Haeng-Ran Seo, Naoual Oukkache
Publikováno v:
Molecules, Vol 27, Iss 7, p 2219 (2022)
Hepatocellular carcinoma (HCC) is the most dominant primary liver cancer, which can be caused by chronic hepatitis virus infections and other environmental factors. Resection, liver transplantation, and local ablation are only a few of the highly eff
Externí odkaz:
https://doaj.org/article/a6c644ea96f344e1948d34a35501ea92
Publikováno v:
BMB Reports. 56:225-233
Autor:
Seo-Hyun Choi, A-Ram Kim, Jae-Kyung Nam, Jin-Mo Kim, Jee-Youn Kim, Haeng Ran Seo, Hae-June Lee, Jaeho Cho, Yoon-Jin Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Radiotherapy is the main treatment for most cancer, but it is unclear if targeting tumour vasculature can enhance tumour radiosensitivity. Here, the authors show that tumour endothelial-mesenchymal transition after radiotherapy leads to proliferation
Externí odkaz:
https://doaj.org/article/1c8be8c45157487b80a64a318466f67b
Autor:
Wookjin Shin, Sang-Kyu Lee, Jeong-Ha Hwang, Jong-Chan Park, Yong-Hee Cho, Eun Ji Ro, Yeonhwa Song, Haeng Ran Seo, Kang-Yell Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 6, Pp 1-10 (2018)
Colorectal cancer: Finding new small molecule drug candidates Mutations in KRAS, a gene regulating cell proliferation, occur in 40–50% of colorectal cancer (CRC) patients. These cancers are usually insensitive to antibody drugs targeting the epider
Externí odkaz:
https://doaj.org/article/17071f805a974c92a2ccacea3e4d43dd
Autor:
Yeonhwa Song, Jin-Sun Kim, Se-Hyuk Kim, Yoon Kyung Park, Eunsil Yu, Ki-Hun Kim, Eul-Ju Seo, Heung-Bum Oh, Han Chu Lee, Kang Mo Kim, Haeng Ran Seo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide and has poor prognosis. Specially, patients with HCC usually have poor tolerance of systemic chemotherapy, because HCCs develop from chronically d
Externí odkaz:
https://doaj.org/article/fa10a60671f847108d40127210cb18b6