Zobrazeno 1 - 10
of 20 069
pro vyhledávání: '"Haemophilia A"'
Quality of Life among Haemophilic Children in Central Madhya Pradesh, India: A Cross-sectional Study
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 08, Pp 19-22 (2024)
Introduction: Quality of Life (QoL) has recently become a focus of research in haemophilia, as children with haemophilia miss out on opportunities to reach their full potential during school and later in life. This leads to emotional and behavioural
Externí odkaz:
https://doaj.org/article/adc5eb7b54e84f8bb999ed2d2bdca84d
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 92-98 (2024)
Patients with acquired haemophilia A (PwAHA) can present with severe bleeding and may require lengthy treatment with bypassing agents and immunosuppression. We present two cases of the implementation of emicizumab in PwAHA. The first patient, an 82-y
Externí odkaz:
https://doaj.org/article/421bc4fc750a4b3db7ed635b111b9b85
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Haemophilia A (HA; Factor VIII deficiency) is a congenital X-linked bleeding disorder characterized by trauma-related or spontaneous bleeding events, most notably arising within the intraarticular space and resulting in chronic in
Externí odkaz:
https://doaj.org/article/8859ab964dce4b81bcfb6f7b77c3f757
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 24, Iss 2, Pp 123-139 (2024)
INTRODICTION. Currently, gene therapy based on adeno-associated virus (AAV) vectors faces a number of barriers, both biomedical and technological, which require studying and overcoming for further development of this gene therapy technology.AIM. This
Externí odkaz:
https://doaj.org/article/71be6780a74542e89f7c57e1138ef4ad
Autor:
Maryam Karimi, Seyed Mahdi Rezayat, Seyed Alireza Mortazavi, Azadeh Haeri, Mahmoud Reza Jaafari
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 6, Pp 747-754 (2024)
Objective(s): Currently, the most important treatment approach for hemophilia type A is recombinant Factor VIII. However, due to its low retention time in the blood, the patients usually need successive injections. In addition, neutralization of inje
Externí odkaz:
https://doaj.org/article/e0d13df8d82847a5990ee667a1a18639
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Introduction Haemophilia A (HA) is an X-linked recessive bleeding disorder caused by lack or deficiency of coagulation factor VIII. Aim The aim of this study is to determine the incidence and treatment-related risk factors of inhibitor devel
Externí odkaz:
https://doaj.org/article/8eb0164de4424175b446695025a81d63
Autor:
Wolfgang Miesbach, Greta Mulders, Daan Breederveld, Karen Pinachyan, Sandra Le Quellec, Ingrid Pabinger
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Adeno-associated virus (AAV)-based gene therapy for haemophilia has advanced substantially in the last 13 years; recently, three products have received approvals from regulatory authorities. Although the impact on quality of life
Externí odkaz:
https://doaj.org/article/8ffb5b42aa32428096d4d247c35af0e4
Autor:
Fletcher Simon
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 78-81 (2024)
With over three decades of nursing experience, Simon reflects on his experience as a research nurse at the Oxford Haemophilia and Thrombosis Centre at a time of huge change for haemophilia care and treatment. He recalls the impact of conversations wi
Externí odkaz:
https://doaj.org/article/a01b5a84a6614a33a4e03cc19a9c39b5
Autor:
Castaman Giancarlo, Mancuso Maria Elisa, Di Minno Matteo Nicola Dario, Sannino Luigi, Tempre Rosaria, Bendinelli Sara, Blenkiron Tom, Burke Tom, Grazzi Enrico Ferri
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 58-68 (2024)
The burden of severe haemophilia A (HA) has been studied extensively owing to the higher bleeding frequency and associated treatment requirements, leaving a clear unmet need for research focused on the burden of mild and moderate HA.
Externí odkaz:
https://doaj.org/article/3a61e7847d834753a8ed57fcde0f4f1d
Autor:
O’Mahony Brian, Fletcher Simon, Baarslag Manuel, Khair Kate, Breederveld Daan, Jansen Nathalie, Pembroke Luke, Pinachyan Karen, Sivasubramaniyam Sujan
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 47-57 (2024)
Gene therapy presents a potentially transformational approach to haemophilia management. The patient journey for gene therapy is unlike that for other haemophilia treatments, and its one-time, irreversible nature has led to broad agreement that infor
Externí odkaz:
https://doaj.org/article/b4272df270e046fc8cf8f06583c6b431