Zobrazeno 1 - 10
of 20 225
pro vyhledávání: '"Haemophilia A"'
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Introduction Haemophilia is a rare bleeding disorder caused by a deficient or absent clotting factor, leading to frequent bleeding. Multiple intravenous (IV) infusions have been the standard prophylactic treatment; however, newer treatment o
Externí odkaz:
https://doaj.org/article/9ab0632c6f214bceb34ae58ed651b7a7
Autor:
Giulia Battafarano, Stefano Lancellotti, Monica Sacco, Michela Rossi, Sara Terreri, Jacopo Di Gregorio, Laura Di Giuseppe, Matteo D’Agostini, Ottavia Porzio, Leonardo Di Gennaro, Maira Tardugno, Simone Pelle, Salvatore Minisola, Renato Maria Toniolo, Matteo Luciani, Andrea Del Fattore, Raimondo De Cristofaro
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Haemophilia is associated with reduced bone mass and mineral density. Due to the rarity of the disease and the heterogeneity among the studies, the pathogenesis of bone loss is still under investigation. We studied the effects of coagulation
Externí odkaz:
https://doaj.org/article/a07d14be5e544bd38d8da6e3ba506cec
Publikováno v:
Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-23 (2024)
Abstract Background Chronic pain is reported by between 30 and 71% of people with haemophilia (PWH). Exercise is shown to be effective for pain management in other arthritides, but it remains unclear if such an approach is effective or acceptable to
Externí odkaz:
https://doaj.org/article/c2428099aee840c49bf674d2086a742f
Autor:
Theresa Ukamaka Nwagha, Helen Chioma Okoye, Charles Emeka Nonyelu, Chioma Sandra Ejezie, Onochie Ikenna Obodo, Megan Adediran
Publikováno v:
Nigerian Journal of Medicine, Vol 32, Iss 6, Pp 600-605 (2024)
Background: Inadequate management of haemophilia in a resource-limited setting may worsen the challenges that haemophilia caregivers face. AIM: The aim of the study was to evaluate the effect of the burden of caring for persons with haemophilia (PWH)
Externí odkaz:
https://doaj.org/article/02be5e0e6dff469ca7c9f772246299f2
Autor:
Bladen Melanie, McDonagh Janet, McLaughlin Paul, Gooding Richard, Holder Kerry-Ann, Thind Sharon, Klooster Brittany, Shields Alan, Turner-Bowker Diane M., Chatterton Kaitlin, Leso Allison, Volpi Connor, Sivasubramaniyam Sujan, Abulizi Jiawula, Khan Nisa
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 108-122 (2024)
Early detection of joint bleeds is challenging yet critical for preserving joint health among individuals with haemophilia. This work explored early indicators of joint bleeds and young people with haemophilia B (YPwHB) self-monitoring practices to d
Externí odkaz:
https://doaj.org/article/2187d05f073840dc9d9acfcd1186f058
Quality of Life among Haemophilic Children in Central Madhya Pradesh, India: A Cross-sectional Study
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 08, Pp 19-22 (2024)
Introduction: Quality of Life (QoL) has recently become a focus of research in haemophilia, as children with haemophilia miss out on opportunities to reach their full potential during school and later in life. This leads to emotional and behavioural
Externí odkaz:
https://doaj.org/article/adc5eb7b54e84f8bb999ed2d2bdca84d
Publikováno v:
The Journal of Haemophilia Practice, Vol 11, Iss 1, Pp 92-98 (2024)
Patients with acquired haemophilia A (PwAHA) can present with severe bleeding and may require lengthy treatment with bypassing agents and immunosuppression. We present two cases of the implementation of emicizumab in PwAHA. The first patient, an 82-y
Externí odkaz:
https://doaj.org/article/421bc4fc750a4b3db7ed635b111b9b85
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Haemophilia A (HA; Factor VIII deficiency) is a congenital X-linked bleeding disorder characterized by trauma-related or spontaneous bleeding events, most notably arising within the intraarticular space and resulting in chronic in
Externí odkaz:
https://doaj.org/article/8859ab964dce4b81bcfb6f7b77c3f757
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 24, Iss 2, Pp 123-139 (2024)
INTRODICTION. Currently, gene therapy based on adeno-associated virus (AAV) vectors faces a number of barriers, both biomedical and technological, which require studying and overcoming for further development of this gene therapy technology.AIM. This
Externí odkaz:
https://doaj.org/article/71be6780a74542e89f7c57e1138ef4ad
Autor:
Maryam Karimi, Seyed Mahdi Rezayat, Seyed Alireza Mortazavi, Azadeh Haeri, Mahmoud Reza Jaafari
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 6, Pp 747-754 (2024)
Objective(s): Currently, the most important treatment approach for hemophilia type A is recombinant Factor VIII. However, due to its low retention time in the blood, the patients usually need successive injections. In addition, neutralization of inje
Externí odkaz:
https://doaj.org/article/e0d13df8d82847a5990ee667a1a18639