Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hae-Jun Hwang"'
Autor:
Seon Uk Kim, Hyun Jung Yoo, Jung Ho Kim, Jin Kyun Park, Eun Young Lee, Yeong Wook Song, Hae Jun Hwang
Background/PurposeRheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by bone and cartilage destruction with leukocyte infiltration and activation at synovial tissue. The fibroblast-like synoviocytes (FLS) have a cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58906d0790bfb43f3a39a610b798ca88
https://doi.org/10.21203/rs.3.rs-126063/v1
https://doi.org/10.21203/rs.3.rs-126063/v1
Autor:
Hae-Jun Hwang, Jin-Mun Jeong
Publikováno v:
Journal of Optimization Theory and Applications. 167:49-67
This paper deals with the time optimal control problem for semilinear retarded functional differential equations by using the construction of the fundamental solution in the case where the principal operators are unbounded. We also present the maximu
Autor:
Sang Jae, Lee, Jang-Sik, Choi, Seoung Min, Bong, Hae-Jun, Hwang, Jaesang, Lee, Ho-Juhn, Song, Jaekyoo, Lee, Jung-Ho, Kim, Jong Sung, Koh, Byung Il, Lee
Publikováno v:
Molecules and Cells
Spleen tyrosine kinase (SYK) is a cytosolic non-receptor protein tyrosine kinase. Because SYK mediates key receptor signaling pathways involving the B cell receptor and Fc receptors, SYK is an attractive target for autoimmune disease and cancer treat
Autor:
Wan Sung Kim, Suji Kim, Sun Uk Bak, Kwon-Soo Ha, Young Myeong Kim, Jung A. Yun, Young Guen Kwon, Ji Yoon Kim, Moo Ho Won, Hae Jun Hwang
Publikováno v:
BMB Reports
Heme oxygenase (HO-1) catalyzes heme to carbon monoxide (CO), biliverdin/bilirubin, and iron and is known to prevent the pathogenesis of several human diseases. We assessed the beneficial effect of heme degradation products on osteoclastogenesis indu
Publikováno v:
Acta Horticulturae. :533-537
Publikováno v:
Acta Horticulturae. :521-526
Autor:
Choi Jang-Sik, Jong Sung Koh, Byung Il Lee, Ho-Juhn Song, Jaekyoo Lee, Hae-Jun Hwang, Phil Ho Lee, Se Won Kim, Jung-Ho Kim
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(20)
A series of pyrazolylpyrimidine scaffold based Syk inhibitors were synthesized and evaluated for their biological activities and selectivity. Lead optimization efforts provided compounds with potent Syk inhibition in both enzymatic and TNF-α release
Autor:
Hae-Jun Hwang, Chi-Woong Rho, Soo-Jin Kim, Kyung-Rak Choi, Hye-Seon Choi, Byung-Sam Kim, Sang-Chul Lee, Tae-Wook Kyung
Publikováno v:
Archives of Pharmacal Research. 29:235-240
The oral administration of extracts of young radishes cultivated with sulfur after intravenous tumor cell injection achieved a marked reduction of pulmonary colonization in mice. Treatment of the mice with extracts of young radish cultivated with sul
Autor:
Nak-Ku Kim, Chang-Suk Kong, Hae-Jun Hwang, Jeung-Ha Kil, Sook-Hee Rhee, Kun-Young Park, Chi-Woong Rho, Soon-Sun Bak
Publikováno v:
Journal of the Korean Society of Food Science and Nutrition. 34:1520-1524
Young radishes (YR, yeolmu in Korean) were cultivated in the soil with and without sulfur. Young radish kimchi-general (YR kimchi-G) was prepared with YR commonly cultivated in the soil without sulfur. Young radish kimchl-sulfur (YR kimchi-S) and you
Autor:
Jong Sung Koh, Kim Jung-Ho, Jung Keun Kim, Se Won Kim, Dong Sik Jung, Jungmi Lee, Hee Kyu Lee, Sang Yeop Lee, Choi Jang-Sik, In Yong Lee, Park Sung-Ho, Jaekyoo Lee, Hong Woo Kim, Hae-Jun Hwang, Jan Cools, Ho-Juhn Song
Publikováno v:
Blood. 123(14)
Aberrant activations of Fms-like tyrosine receptor kinase (FLT) 3 are implicated in the pathogenesis of 20% to 30% of patients with acute myeloid leukemia (AML). G-749 is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3