Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Hae Ki Min"'
Autor:
Yaping Wang, Pandak, Williams M., Hylemon, Phillip B., Hae-Ki Min, Min, John, Fuchs, Michael, Sanyal, Arun J., Shunlin Ren
Publikováno v:
American Journal of Physiology: Gastrointestinal & Liver Physiology; Feb2024, Vol. 326 Issue 2, pG147-G162, 16p
Autor:
Ekaterina, Smirnova, Mark D, Muthiah, Nicole, Narayan, Mohamad S, Siddiqui, Puneet, Puri, Velimir A, Luketic, Melissa J, Contos, Michael, Idowu, Jen-Chieh, Chuang, Andrew N, Billin, Ryan S, Huss, Robert P, Myers, Sherry, Boyett, Mulugeta, Seneshaw, Hae-Ki, Min, Faridodin, Mirshahi, Arun J, Sanyal
Publikováno v:
Hepatology. 76:1811-1824
Bile acids are hepatic metabolites and have many properties considered to be relevant to the pathophysiology of NAFLD. Circulating levels of the intestinal microbiome-modified bile acid deoxycholate are increased in cirrhosis.To further elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e9c204e496a981fe3b9eb32acb3053
https://doi.org/10.1002/hep.32568
https://doi.org/10.1002/hep.32568
Autor:
Puneet Puri, Jun Xu, Terhi Vihervaara, Riikka Katainen, Kim Ekroos, Kalyani Daita, Hae-Ki Min, Andrew Joyce, Faridoddin Mirshahi, Hidekazu Tsukamoto, Arun J. Sanyal
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 6, Pp 1017-1028 (2016)
Alcohol- and obesity-related liver diseases often coexist. The hepatic lipidomics due to alcohol and obesity interaction is unknown. We characterized the hepatic lipidome due to 1) alcohol consumption in lean and obese mice and 2) obesity and alcohol
Externí odkaz:
https://doaj.org/article/b309144f2b9d42c4bb0329c40f324e0f
Autor:
Faridoddin Mirshahi, Sophie C. Cazanave, Prasanna K. Santhekadur, Bubu A. Banini, Divya P. Kumar, Abdul M. Oseini, Hae Ki Min, Liangsu Wang, Pierre Bedossa, Mulugeta Seneshaw, Cristina Alonso, Hong Ping Guan, Srinivas V. Koduru, Arun J. Sanyal
Publikováno v:
Hepatology. 73:1290-1306
BACKGROUND AND AIMS The mechanisms by which the I148M mutant variant of the patatin-like phospholipase domain-containing 3 (PNPLA3I148M ) drives development of nonalcoholic steatohepatitis (NASH) are not known. The aim of this study was to obtain ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::230a2349a46562bcb088f20fd22afdeb
https://doi.org/10.1002/hep.31609
https://doi.org/10.1002/hep.31609
Autor:
Tommy Pacana, Sophie Cazanave, Aurora Verdianelli, Vaishali Patel, Hae-Ki Min, Faridoddin Mirshahi, Eoin Quinlivan, Arun J Sanyal
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136822 (2015)
Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The mechanisms by which these are affected in NAFLD are not fully understood. The aim is to perfor
Externí odkaz:
https://doaj.org/article/595118a6fdf147bc9bbdf5b5110d71f0
Autor:
Shunlin Ren, Jin Koung Kim, Genta Kakiyama, Daniel Rodriguez-Agudo, William M Pandak, Hae-Ki Min, Yanxia Ning
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103621 (2014)
Oxysterol sulfation plays an important role in regulation of lipid metabolism and inflammatory responses. In the present study, we report the discovery of a novel regulatory sulfated oxysterol in nuclei of primary rat hepatocytes after overexpression
Externí odkaz:
https://doaj.org/article/e8250311858644149af3890f2efe236f
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114944 (2014)
The human tryptase locus on chromosome 16 contains one gene encoding only β-tryptase and another encoding either β-tryptase or the homologous α-tryptase, providing α:β gene ratios of 0:4, 1:3 or 2:2 in the diploid genome, these genotypes being o
Externí odkaz:
https://doaj.org/article/61412c8a2bc24ea488907b33baf8f8ff
Autor:
Andrea L. Webber, Kristian K. Jensen, Arun J. Sanyal, Robert Vincent, Alexei A. Podtelezhnikov, Bubu A. Banini, Divya P. Kumar, Hae-Ki Min, Keith Q. Tanis, Sophie C. Cazanave, Prasanna K. Santhekadur, Abdul M. Oseini, Faridoddin Mirshahi, Liangsu Wang, Adolfo G Mauro, Mulugeta Seneshaw, Pierre Bedossa
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
A longitudinal molecular model of the development and progression of nonalcoholic fatty liver disease (NAFLD) over time is lacking. We have recently validated a high fat/sugar water-induced animal (an isogenic strain of C57BL/6 J:129S1/SvImJ mice) mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a80a8ccf95afc52cda74aa8366fb716
http://europepmc.org/articles/PMC7225167
http://europepmc.org/articles/PMC7225167
Autor:
Mohammad S. Siddiqui, Hae-Ki Min, Andrew Joyce, Arun J. Sanyal, Rohit Kohli, Prasanna K. Santhekadur, Sophie C. Cazanave, Puneet Puri, Divya P. Kumar, Michael O. Idowu, Kalyani Daita, Melissa J. Contos, Velimir A. Luketic, Phillip B. Hylemon, Huiping Zhou, Sherry Boyett, Faridoddin Mirshahi
Publikováno v:
Hepatology. 67:534-548
The histologic spectrum of nonalcoholic fatty liver disease (NAFLD) includes fatty liver (NAFL) and steatohepatitis (NASH), which can progress to cirrhosis in up to 20% NASH patients. Bile acids (BA) are linked to pathogenesis and therapy of NASH. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76aa785229071dc26fc64d11cf1ff867
https://doi.org/10.1002/hep.29359
https://doi.org/10.1002/hep.29359
Publikováno v:
Metabolism. 71:83-93
Background Oxysterol sulfation plays a fundamental role in the regulation of many biological events. Its products, 25-hydroxycholesterol 3-sulfate (25HC3S) and 25-hydroxycholesterol 3, 25-disulfate (25HCDS), have been demonstrated to be potent regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1307b75c17d33f91c452b707153f63
https://doi.org/10.1016/j.metabol.2016.12.007
https://doi.org/10.1016/j.metabol.2016.12.007