Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hadrien, Peyret"'
Autor:
Sophie E. Roberts, Heather L. Martin, Danah Al-Qallaf, Anna A. Tang, Christian Tiede, Thembaninkosi G. Gaule, Albor Dobon-Alonso, Ross Overman, Sachin Shah, Hadrien Peyret, Keith Saunders, Robin Bon, Iain W. Manfield, Sandra M. Bell, George P. Lomonossoff, Valerie Speirs, Darren C. Tomlinson
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110461- (2024)
Summary: Monoclonal antibodies have revolutionized therapies, but non-immunoglobulin scaffolds are becoming compelling alternatives owing to their adaptability. Their ability to be labeled with imaging or cytotoxic compounds and to create multimeric
Externí odkaz:
https://doaj.org/article/afbbfa1f915d4d408b05c261d3880b47
Autor:
Keith Saunders, Eva C. Thuenemann, Sachin N. Shah, Hadrien Peyret, Ruth Kristianingsih, Sergio G. Lopez, Jake Richardson, George P. Lomonossoff
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The production of designer-length tobacco mosaic virus (TMV) nanorods in plants has been problematic in terms of yields, particularly when modified coat protein subunits are incorporated. To address this, we have investigated the use of a replicating
Externí odkaz:
https://doaj.org/article/770666d1984648379319e5e8a008761a
Publikováno v:
Plant Methods, Vol 15, Iss 1, Pp 1-13 (2019)
Abstract Background The growing field of plant molecular farming relies on expression vectors that allow high yields of recombinant proteins to be produced through transient gene expression. While numerous expression vectors currently exist for this
Externí odkaz:
https://doaj.org/article/a224ae9d8c334c5a8e4a5b516ab16bf3
Autor:
Hadrien Peyret, John F. C. Steele, Jae-Wan Jung, Eva C. Thuenemann, Yulia Meshcheriakova, George P. Lomonossoff
Publikováno v:
Vaccines, Vol 9, Iss 7, p 780 (2021)
The past 30 years have seen the growth of plant molecular farming as an approach to the production of recombinant proteins for pharmaceutical and biotechnological uses. Much of this effort has focused on producing vaccine candidates against viral dis
Externí odkaz:
https://doaj.org/article/20e45d578d1945a18793daa31dc91e0c
Autor:
Ee Leen Pang, Hadrien Peyret, Alex Ramirez, Hwei-San Loh, Kok-Song Lai, Chee-Mun Fang, William M. Rosenberg, George P. Lomonossoff
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Dengue fever is currently ranked as the top emerging tropical disease, driven by increased global travel, urbanization, and poor hygiene conditions as well as global warming effects which facilitate the spread of Aedes mosquitoes beyond their current
Externí odkaz:
https://doaj.org/article/8b169e1df4774f27af21d3ef71ae01a8
Autor:
Eugenio Benvenuto, Inge Broer, Marc-André D’Aoust, Inga Hitzeroth, Penny Hundleby, Rima Menassa, Kirsi-Marja Oksman-Caldentey, Hadrien Peyret, Sancha Salgueiro, Pooja Saxena, Jennifer Stander, Heribert Warzecha, Julian Ma
Publikováno v:
Nature Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e72e0bfcc6c8c82869cb98876fc764
https://doi.org/10.1038/s41587-023-01812-w
https://doi.org/10.1038/s41587-023-01812-w
Autor:
Eva C. Thuenemann, Matthew J. Byrne, Hadrien Peyret, Keith Saunders, Roger Castells-Graells, Inmaculada Ferriol, Mattia Santoni, John F. C. Steele, Neil A. Ranson, Linda Avesani, Juan Jose Lopez-Moya, George P. Lomonossoff
Publikováno v:
Viruses, Vol 13, Iss 5, p 885 (2021)
The production of plant helical virus-like particles (VLPs) via plant-based expression has been problematic with previous studies suggesting that an RNA scaffold may be necessary for their efficient production. To examine this, we compared the accumu
Externí odkaz:
https://doaj.org/article/2ba02e7ef9e8407fa6b0d37317efde36
Autor:
Gergana Zahmanova, Milena Mazalovska, Katerina Takova, Valentina Toneva, Ivan Minkov, Hadrien Peyret, George Lomonossoff
Publikováno v:
Life, Vol 11, Iss 1, p 64 (2021)
The core antigen of hepatitis B virus (HBcAg) is capable of self-assembly into virus-like particles (VLPs) when expressed in a number of heterologous systems. Such VLPs are potential carriers of foreign antigenic sequences for vaccine design. In this
Externí odkaz:
https://doaj.org/article/0225d3a7c678437abf9cc13f97102b28
Autor:
Hadrien, Peyret, George P, Lomonossoff
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2480
Recent discoveries in the dynamics of genome replication and packaging in the plant virus Cowpea mosaic virus (CPMV) has led to the development of a novel method for specifically packaging an RNA molecule of choice into virus-like particles (VLPs) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52cb98287bdd6c11e9b89a0380379323
https://pubmed.ncbi.nlm.nih.gov/35616860
https://pubmed.ncbi.nlm.nih.gov/35616860
Autor:
Albor Dobon Alonso, Eva C. Thuenemann, Nicholas Holton, George P. Lomonossoff, Martin Stocks, Emma Kennedy, Hadrien Peyret, Ross Overman, Yulia Meshcheriakova, Daniel Ponndorf, Stuart D. Dowall
Publikováno v:
Plant Biotechnology Journal
Summary Dengue virus (DENV) is an emerging threat causing an estimated 390 million infections per year. Dengvaxia, the only licensed vaccine, may not be adequately safe in young and seronegative patients; hence, development of a safer, more effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a01ccf364927b062e0c69aa63591d2
https://doi.org/10.1111/pbi.13501
https://doi.org/10.1111/pbi.13501