Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hadia Lemar"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/991fa3acc4f147c0b5344e80fea27c3b
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e2589af03ce0954e44bac03c1da145
https://doi.org/10.1136/jitc-2022-sitc2022.0902
https://doi.org/10.1136/jitc-2022-sitc2022.0902
Autor:
Michael Whang, Ming-Hong Xie, Kate Jamboretz, Chang Kim, Sombeet Sahu, Hadia Lemar, Nafees Rahman, Ivan Chan, Erik Whiteley, Ralph Brandenberger, Sasha Lazetic, James Trager
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a09b5569a279ae127f9293fbee15b82
https://doi.org/10.1136/jitc-2022-sitc2022.0381
https://doi.org/10.1136/jitc-2022-sitc2022.0381
Autor:
Andrea Olga Andrea Olga Shorts, Aaron P. Yamniuk, Keith S. Bahjat, Radha Ramakrishnan, Gaëlle Martin, Sanjib Dutta, David A Critton, Hua Fang, Dibella Rose A, Kader Thiam, Lynne Campbell, Arathi Krishnakumar, Burce Ergel, Martin J. Corbett, Haibin Chen, Robert J. Johnston, Richard Y.-C. Huang, Alan J. Korman, Joseph M. Rizzo, Thomas Cayton, Zheng Yang, Michael Quigley, Jason Pinckney, Ying-Kai Wang, Ginger Rakestraw, Justine Ngo, Paul O. Sheppard, Linhui Julie Su, Andrew Rankin, Jim Holloway, Xiaodi Deng, Akbar Nayeem, Arvind Rajpal, Eric Boyer, Hadia Lemar, Alexander T. Kozhich
Publikováno v:
Nature. 574:565-570
Co-inhibitory immune receptors can contribute to T cell dysfunction in patients with cancer1,2. Blocking antibodies against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) partially reverse this effect and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f81db0a515c56824b63859d10463a7
https://doi.org/10.1038/s41586-019-1674-5
https://doi.org/10.1038/s41586-019-1674-5
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundNK cells expanded on membrane-bound (mb) IL-15 and 41BBL expressing K562 stimulatory cells (NKSTIM) for clinical use can be genetically modified to express activating chimeric receptors.1 2 3 NK cells activated in the presence of IL-12, IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1523b6ffe1a81efea391160a9a0e5a9e
https://doi.org/10.1136/jitc-2021-sitc2021.128
https://doi.org/10.1136/jitc-2021-sitc2021.128
Autor:
Ralph Brandenberger, Ming-Hong Xie, Sasha Lazetic, Nafees Rahman, Hadia Lemar, Chao Guo, James B. Trager, Kate Jamboretz, Ivan H. Chan, Michael Whang, Erik Michael Whiteley
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A159-A159
BackgroundPeripheral blood natural killer (NK) cells are mature cytotoxic innate lymphocytes possessing an inherent capacity for tumor cell killing, thus making them attractive candidates for adoptive cell therapy. These NK cells are also amenable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc35e391396f0dc235d039daedcdf73d
https://doi.org/10.1136/jitc-2021-sitc2021.151
https://doi.org/10.1136/jitc-2021-sitc2021.151
Autor:
Hadia Lemar, Michael Patrick Dillon, Marcos Gonzalez-Lopez, Candy Garcia, James Joseph, Fred Aswad, Christina Galang, Jeffrey H. Hager
Publikováno v:
Cancer Research. 79:3255-3255
Tumor associated macrophages, mainly represented by the M2-like phenotype, are a highly immunosuppressive macrophage subset that exert a pro-tumorigenic role in a variety of cancer types. Understanding the factors that promote M2 macrophage different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b442ec8341d12d0198574a47235b0e
https://doi.org/10.1158/1538-7445.am2019-3255
https://doi.org/10.1158/1538-7445.am2019-3255
Autor:
Muzaffar Alam, Marcos Gonzalez-Lopez, Jeffrey H. Hager, Bing Yao, Kedar S. Vaidya, Marcus Fischer, Christina Galang, Candy Garcia, Jing Lu, Eleni Venetsanakos, James Joseph, Michael Patrick Dillon, Christian Frey, Hadia Lemar, Fred Aswad
Publikováno v:
Cancer Research. 78:4719-4719
Cancer cells utilize a variety of pathways to generate an immune permissive growth environment and evade the host anti-tumor immune response. One such pathway is production of T-cell inhibitory tryptophan (Trp) metabolites, kynurenine and kynurenic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01bfd12b6665a630be564a06f7a84077
https://doi.org/10.1158/1538-7445.am2018-4719
https://doi.org/10.1158/1538-7445.am2018-4719
Autor:
Alan J. Korman, Marco A. Coccia, Mark J. Selby, Hadia Lemar, Ben Preston, Diane Feingersh, Alison Witte, Jon Terrett
Publikováno v:
Clinical Immunology. 123:S121-S122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e751815aa2e2033305ad4aa57afb21f8
https://doi.org/10.1016/j.clim.2007.03.524
https://doi.org/10.1016/j.clim.2007.03.524