Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hadi Valadi"'
Autor:
Hernán González‐King, Patricia G. Rodrigues, Tamsin Albery, Benyapa Tangruksa, Ramya Gurrapu, Andreia M. Silva, Gentian Musa, Dominika Kardasz, Kai Liu, Bengt Kull, Karin Åvall, Katarina Rydén‐Markinhuhta, Tania Incitti, Nitin Sharma, Cecilia Graneli, Hadi Valadi, Kasparas Petkevicius, Miguel Carracedo, Sandra Tejedor, Alena Ivanova, Sepideh Heydarkhan‐Hagvall, Phillipe Menasché, Jane Synnergren, Niek Dekker, Qing‐Dong Wang, Karin Jennbacken
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Small extracellular vesicles (sEV) derived from various cell sources have been demonstrated to enhance cardiac function in preclinical models of myocardial infarction (MI). The aim of this study was to compare different sources of sEV for ca
Externí odkaz:
https://doaj.org/article/c768354e5bb04d27b8a38ee892355c5b
Autor:
Muhammad Nawaz, Sepideh Heydarkhan‐Hagvall, Benyapa Tangruksa, Hernán González‐King Garibotti, Yujia Jing, Marco Maugeri, Franziska Kohl, Leif Hultin, Azadeh Reyahi, Alessandro Camponeschi, Bengt Kull, Jonas Christoffersson, Ola Grimsholm, Karin Jennbacken, Martina Sundqvist, John Wiseman, Abdel Wahad Bidar, Lennart Lindfors, Jane Synnergren, Hadi Valadi
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an
Externí odkaz:
https://doaj.org/article/cd41eb4a09a4418b8e2864914218e324
Autor:
Umme Habiba, Aafia Malik, Ghazala Kaukab Raja, Muhammad Raza Memon, Asad Tameezud din Nizami, Rafaqat Ishaq, Muhammad Ilyas, Hadi Valadi, Muhammad Nawaz, Pakeeza Arzoo Shaiq
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 407 (2023)
Schizophrenia patients demonstrate variations in response to different therapies that are currently being used for the treatment of disorders, such as augmentation therapy (ECT or mood stabilizer) and combination therapy (with antipsychotics). These
Externí odkaz:
https://doaj.org/article/9d2d188be3e446c2bb04ea6729a32c33
Autor:
Chiara Franco, Anna Ghirardello, Loris Bertazza, Michela Gasparotto, Elisabetta Zanatta, Luca Iaccarino, Hadi Valadi, Andrea Doria, Mariele Gatto
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3663 (2023)
There is still a need for an efficient method for the isolation of extracellular vesicles (EVs) from human blood that provides a reliable yield with acceptable purity. Blood is a source of circulating EVs, but soluble proteins and lipoproteins hamper
Externí odkaz:
https://doaj.org/article/e134efbc1a744b068dfe9b99e6b4516d
Autor:
Muhammad Saqlain, Madiha Khalid, Muhammad Fiaz, Sadia Saeed, Asad Mehmood Raja, Muhammad Mobeen Zafar, Tahzeeb Fatima, João Bosco Pesquero, Cristina Maglio, Hadi Valadi, Muhammad Nawaz, Ghazala Kaukab Raja
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Obesity is highly polygenic disease where several genetic variants have been reportedly associated with obesity in different ethnicities of the world. In the current study, we identified the obesity risk or protective association and BMI raising effe
Externí odkaz:
https://doaj.org/article/c4e59491074e444d94f6656183f5526b
Autor:
Muhammad Mobeen Zafar, Muhammad Saqlain, Asad Mehmood Raja, Pakeeza Arzoo Shaiq, Muhammad Javaid Asad, Muhammad Kausar Nawaz Shah, Farah Fatima, Hadi Valadi, Muhammad Nawaz, Ghazala Kaukab Raja
Publikováno v:
Genes, Vol 13, Iss 12, p 2226 (2022)
The world population is genetically predisposed to metabolic syndrome (MetS) and its components, also known as cardiometabolic risk phenotypes, which can cause severe health complications including coronary heart disease (CHD). Genetic variants in th
Externí odkaz:
https://doaj.org/article/06d12cadf15b48a0859d8024926149f5
Autor:
Marco Maugeri, Muhammad Nawaz, Alexandros Papadimitriou, Annelie Angerfors, Alessandro Camponeschi, Manli Na, Mikko Hölttä, Pia Skantze, Svante Johansson, Martina Sundqvist, Johnny Lindquist, Tomas Kjellman, Inga-Lill Mårtensson, Tao Jin, Per Sunnerhagen, Sofia Östman, Lennart Lindfors, Hadi Valadi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Lipid nanoparticles (LNPs) are potential platforms for RNA-based therapeutics, but the fate of LNP-RNAs upon internalization into the cell is unclear. Here, the authors show that LNP-mRNAs and ionizable lipids escape the endosomes and are re-released
Externí odkaz:
https://doaj.org/article/8b2d6ac14e79424d88fcb0a687a8a932
Autor:
Iram Mushtaq, Zainab Bashir, Mehvish Sarwar, Maria Arshad, Ayesha Ishtiaq, Wajiha Khan, Uzma Khan, Sobia Tabassum, Tahir Ali, Tahzeeb Fatima, Hadi Valadi, Muhammad Nawaz, Iram Murtaza
Publikováno v:
Molecules, Vol 26, Iss 23, p 7285 (2021)
Metabolic disorders often lead to cardiac complications. Metabolic deregulations during diabetic conditions are linked to mitochondrial dysfunctions, which are the key contributing factors in cardiac hypertrophy. However, the underlying mechanisms in
Externí odkaz:
https://doaj.org/article/aca4863ad0794d579347ccfbf1259a8b
Autor:
Pradeep Kumar Kopparapu, Meghshree Deshmukh, Zhicheng Hu, Majd Mohammad, Marco Maugeri, Friedrich Götz, Hadi Valadi, Tao Jin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7099 (2021)
Staphylococcal aureus (S. aureus), a Gram-positive bacteria, is known to cause various infections. Extracellular vesicles (EVs) are a heterogeneous array of membranous structures secreted by cells from all three domains of life, i.e., eukaryotes, bac
Externí odkaz:
https://doaj.org/article/8f872b1d884e490c8305cb6b4096a568
Autor:
Luisa Statello, Marco Maugeri, Elena Garre, Muhammad Nawaz, Jessica Wahlgren, Alexandros Papadimitriou, Christina Lundqvist, Lennart Lindfors, Anna Collén, Per Sunnerhagen, Marco Ragusa, Michele Purrello, Cinzia Di Pietro, Natalie Tigue, Hadi Valadi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195969 (2018)
The RNA that is packaged into exosomes is termed as exosomal-shuttle RNA (esRNA); however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely unknown. We hypothesized that RNA binding proteins (RBPs) could serve as key p
Externí odkaz:
https://doaj.org/article/b2cf47c08cfc43138c14c6816952d28f