Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hadi Al Shamaileh"'
Autor:
Wang Yin, Cuong V. Pham, Tao Wang, Hadi Al Shamaileh, Rocky Chowdhury, Shweta Patel, Yong Li, Lingxue Kong, Yingchu Hou, Yimin Zhu, Sunrui Chen, Huo Xu, Lee Jia, Wei Duan, Dongxi Xiang
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1623 (2022)
Doxorubicin is the most frequently used chemotherapeutic agent for the treatment of hepatocellular carcinoma. However, one major obstacle to the effective management of liver cancer is the drug resistance derived from the cancer stem cells. Herein, w
Externí odkaz:
https://doaj.org/article/da3b19ab82ab426ba6db578ab9470fde
Autor:
Yingchun Hou, Chunwen Pu, Michael P. Gantier, Hadi Al. Shamaileh, Tao Wang, Peng Wang, Dongxi Xiang, Weihong Zhang, Sarah Shigdar, Wang Yin, Lan Wang, Wei Duan, Shu-Feng Zhou
Publikováno v:
Cancer Letters. 387:77-83
As one of the life-threatening diseases involving multi-step genetic and epigenetic disorders, cancer has long been a dynamic research area for siRNA-based therapy as half of the current siRNA-based clinical trials are involved in oncology. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a436327e9959c6bda3ca558ddd2261
https://doi.org/10.1016/j.canlet.2016.03.045
https://doi.org/10.1016/j.canlet.2016.03.045
Autor:
Liang Qiao, Dongxi Xiang, Shu-Feng Zhou, Sarah Shigdar, Chunwen Pu, Ming Q. Wei, Yimin Zhu, Greg G. Qiao, Yong Li, Hadi Al. Shamaileh, Wei Duan, Conglong Zheng
Publikováno v:
Current Gene Therapy. 15:109-119
Cancer as a genetic disorder is one of the leading causes of death worldwide. Conventional anticancer options such as chemo- and/or radio-therapy have their own drawbacks and could not provide a cure in most cases at present. More effective therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0eff034695bc7750267b926382c98e
https://doi.org/10.2174/1566523214666141224095105
https://doi.org/10.2174/1566523214666141224095105
Autor:
Vasanthanathan Poongavanam, Vigneshwaran Namasivayam, Murugesan Vanangamudi, Hadi Al Shamaileh, Rakesh N Veedu, Jan Kihlberg, N Arul Murugan
Publikováno v:
WIREs Computational Molecular Science. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da58d9533cec1f39e9105387f654f0b3
https://doi.org/10.1002/wcms.1356
https://doi.org/10.1002/wcms.1356
Autor:
Jan Kihlberg, Rakesh N. Veedu, N. Arul Murugan, Hadi Al. Shamaileh, Murugesan Vanangamudi, Vigneshwaran Namasivayam, Vasanthanathan Poongavanam
Publikováno v:
WIREs Computational Molecular Science. 8
The design of inhibitors for human immunodeficiency virus type-1 reverse transcriptase (HIV-1 RT) is one of the most successful approaches for the treatment of HIV infections. Among the HIV-1 RT in ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e613ff99317d96f63ae6cca3ffbc6950
https://doi.org/10.1002/wcms.1328
https://doi.org/10.1002/wcms.1328
Autor:
Tao Wang, Yong Li, Phuong H.L. Tran, Yingchun Hou, Aina He, Lingxue Kong, Roberto A. Barrero, Shu-Feng Zhou, Wang Yin, Hadi Al. Shamaileh, Pei Zhuo Zhang, Wenrong Yang, Dongxi Xiang, Wei Duan, Sarah Shigdar, Matthew Bruce, Ke Liu, Andrew G. D. Bean, Motilal Mathesh
Publikováno v:
Theranostics
Chemotherapy-resistant cancer stem cells (CSCs) are a major obstacle to the effective treatment of many forms of cancer. To overcome CSC chemo-resistance, we developed a novel system by conjugating a CSC-targeting EpCAM aptamer with doxorubicin (Apt-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20854bde813039f6cacd33f0b7bb25e
https://pubmed.ncbi.nlm.nih.gov/29158811
https://pubmed.ncbi.nlm.nih.gov/29158811
Cancer is a malignant disease that affects millions of people worldwide and is one of the leading causes of death. An emerging new class of drugs known as aptamers shows promising potential in targeting cancer stem cells (CSC) for therapeutic and dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6213a0514494571a442b0fb573add0f5
https://doi.org/10.1201/b20047-5
https://doi.org/10.1201/b20047-5
Autor:
Shu-Feng Zhou, Chun Guang Li, Tao Wang, Michael O’Connor, Liang Qiao, Sarah Shigdar, Dongxi Xiang, Joanna Macdonald, Lingxue Kong, Ming Q. Wei, Wei Duan, Yimin Zhu, Hadi Al. Shamaileh, Santanu Bhattacharya
Publikováno v:
Scopus-Elsevier
Sensors (Basel, Switzerland)
Sensors, Vol 13, Iss 10, Pp 13624-13637 (2013)
Sensors (Basel, Switzerland)
Sensors, Vol 13, Iss 10, Pp 13624-13637 (2013)
Aptamers, and the selection process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX) used to generate them, were first described more than twenty years ago. Since then, there have been numerous modifications to the selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a2f6886922adb08a43324afb4d913f
https://doi.org/10.3390/s131013624
https://doi.org/10.3390/s131013624
Autor:
Lasse Holm Lauridsen, Jagat R. Kanwar, Peter R. Dodd, Hadi Al. Shamaileh, Rudi K. Tannenberg, Rakesh N. Veedu
Publikováno v:
Current Alzheimer research. 10(4)
Deposition of amyloid-β (Aβ) peptides in the brain is a central event in the pathogenesis of Alzheimer’s disease (AD), which makes Aβ peptides a crucial target for therapeutic intervention. Significant efforts have been made towards the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa88e034af78d57a84746ce6cfdb2e6
https://pubmed.ncbi.nlm.nih.gov/23270374
https://pubmed.ncbi.nlm.nih.gov/23270374
Publikováno v:
Lauridsen, L H, Shamaileh, H A, Edwards, S L, Taran, E & Veedu, R N 2012, ' Rapid One-Step Selection Method for Generating Nucleic Acid Aptamers: Development of a DNA Aptamer against alpha-Bungarotoxin ', P L o S One, vol. 7, no. 7, pp. e41702 . https://doi.org/10.1371/journal.pone.0041702
PLoS ONE, Vol 7, Iss 7, p e41702 (2012)
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e41702 (2012)
PLoS ONE
Background Nucleic acids based therapeutic approaches have gained significant interest in recent years towards the development of therapeutics against many diseases. Recently, research on aptamers led to the marketing of Macugen®, an inhibitor of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b418c6ffec851aa0af89b152da78d8
https://orbit.dtu.dk/en/publications/a18c8349-6a4b-4d79-9aa4-7c858643c58b
https://orbit.dtu.dk/en/publications/a18c8349-6a4b-4d79-9aa4-7c858643c58b