Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hadhimulya Asmara"'
Autor:
Xiaoqin Zhan, Hadhimulya Asmara, Ning Cheng, Giriraj Sahu, Eduardo Sanchez, Fang-Xiong Zhang, Gerald W. Zamponi, Jong M. Rho, Ray W. Turner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Fragile X Mental Retardation Protein regulates synaptic plasticity and its loss results in Fragile X Syndrome. Here, the authors show that the FMRP(1-297)-tat peptide can permeate the BBB, restore protein translation and mossy fiber LTP, and reduce e
Externí odkaz:
https://doaj.org/article/14f1b5ef2d044bbe97bc456fbccfe24c
Autor:
Hadhimulya Asmara, Ileana Micu, Arsalan P. Rizwan, Giriraj Sahu, Brett A. Simms, Fang-Xiong Zhang, Jordan D. T. Engbers, Peter K. Stys, Gerald W. Zamponi, Ray W. Turner
Publikováno v:
Molecular Brain, Vol 10, Iss 1, Pp 1-15 (2017)
Abstract Calmodulin (CaM) is an important signaling molecule that regulates a vast array of cellular functions by activating second messengers involved in cell function and plasticity. Low voltage-activated calcium channels of the Cav3 family have th
Externí odkaz:
https://doaj.org/article/6b30ca7a1d8445b281ceed3254df4263
Autor:
Brian King, Arsalan P. Rizwan, Hadhimulya Asmara, Norman C. Heath, Jordan D.T. Engbers, Steven Dykstra, Theodore M. Bartoletti, Shahid Hameed, Gerald W. Zamponi, Ray W. Turner
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 175-182 (2015)
Control over the frequency and pattern of neuronal spike discharge depends on Ca2+-gated K+ channels that reduce cell excitability by hyperpolarizing the membrane potential. The Ca2+-dependent slow afterhyperpolarization (sAHP) is one of the most pro
Externí odkaz:
https://doaj.org/article/2b8f5dd89d34414889368d339be70fe0
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 397-404 (2010)
Although calmodulin binding to various sites of the Cav1.2 Ca2+ channel has been reported, the mechanism of the interaction is not fully understood. In this study we examined calmodulin binding to fragment channel peptides using a semi-quantitative p
Externí odkaz:
https://doaj.org/article/4d21783f778f430b9811f0ce841ad959
Autor:
Gerald W. Zamponi, Fang-Xiong Zhang, Eduardo Sanchez, Giriraj Sahu, Ning Cheng, Hadhimulya Asmara, Jong M. Rho, Xiaoqin Zhan, Ray W. Turner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Fragile X Syndrome results from a loss of Fragile X Mental Retardation Protein (FMRP). We now show that FMRP is a member of a Cav3-Kv4 ion channel complex that is known to regulate A-type potassium current in cerebellar granule cells to produce mossy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b8a54f76dc69cf25782e0b197b2e0d
https://doaj.org/article/14f1b5ef2d044bbe97bc456fbccfe24c
https://doaj.org/article/14f1b5ef2d044bbe97bc456fbccfe24c
Publikováno v:
The Journal of Neuroscience. 37:11255-11270
CaV1 L-type calcium channels are key to regulating neuronal excitability, with the range of functional roles enhanced by interactions with calmodulin, accessory proteins, or CaMKII that modulate channel activity. In hippocampal pyramidal cells, a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bd21a3ee57c5204f06b9c432ac00a20
https://doi.org/10.1523/jneurosci.0967-17.2017
https://doi.org/10.1523/jneurosci.0967-17.2017