Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hadas Shasha-Lavsky"'
Autor:
Yaacov Frishberg, Wesley Hayes, Hadas Shasha-Lavsky, David J. Sas, Mini Michael, Anne-Laure Sellier-Leclerc, Julien Hogan, Richard Willey, John M. Gansner, Daniella Magen
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundPrimary hyperoxaluria type 1 (PH1) is a genetic disorder resulting in overproduction of hepatic oxalate, potentially leading to recurrent kidney stones, nephrocalcinosis, chronic kidney disease, and kidney failure. Lumasiran, the first RNA
Externí odkaz:
https://doaj.org/article/22831d3639fc447396b0f620921112a5
Autor:
Sally A. Hulton, Jaap W. Groothoff, Yaacov Frishberg, Michael J. Koren, J. Scott Overcash, Anne-Laure Sellier-Leclerc, Hadas Shasha-Lavsky, Jeffrey M. Saland, Wesley Hayes, Daniella Magen, Shabbir H. Moochhala, Martin Coenen, Eva Simkova, Sander F. Garrelfs, David J. Sas, Kristin A. Meliambro, Taylor Ngo, Marianne T. Sweetser, Bahru A. Habtemariam, John M. Gansner, Tracy L. McGregor, John C. Lieske
Publikováno v:
Kidney International Reports, Vol 7, Iss 3, Pp 494-506 (2022)
Introduction: Primary hyperoxaluria type 1 (PH1) is a rare genetic disease caused by hepatic overproduction of oxalate, leading to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. In the 6-month double-blind period (DBP) of ILL
Externí odkaz:
https://doaj.org/article/d1c32da830c840358e1a339f45ee8a45
Autor:
Hadas Shasha-Lavsky, Aviv Avni, Ziv Paz, Limor Kalfon, Amiel A. Dror, Orly Yakir, Tzipora Falik Zaccai, Irith Weissman
Publikováno v:
Pediatric Nephrology. 38:1811-1820
Autor:
null John Lieske, Jeffrey Saland, Jaap Groothoff, Yaacov Frishberg, Hadas Shasha-Lavsky, Daniella Magen, Shabbir Moochhala, Eva Simkova, Martin Coenen, Wesley Hayes, Julien Hogan, Anne-Laure Sellier-Leclerc, Yinggu Bao, John Gansner, Sally-Anne Hulton
Publikováno v:
Journal of Urology. 209
Autor:
David J. Sas, Daniella Magen, Wesley Hayes, Hadas Shasha-Lavsky, Mini Michael, Indra Schulte, Anne-Laure Sellier-Leclerc, Jiandong Lu, Ali Seddighzadeh, Bahru Habtemariam, Tracy L. McGregor, Kenji P. Fujita, Yaacov Frishberg, Justine Bacchetta, Véronique Baudouin, Rachel Becker-Cohen, Shimrit Tzvi Behr, Efrat Ben-Shalom, Maria Berdaguer, Detlef Bockenhauer, Pierre Cochat, Martin Coenen, Carl H. Cramer, Georges Deschênes, Claire Dossier, Emilie Doye, Liat Feraru Feldman, Maximilian Hohenadel, Florentia Kaguelidou, Irina Libinson Zebegret, John C. Lieske, Anne Maisin, Dawn S. Milliner, Moran Plonsky Toder, Shirley Pollack, Aurélie Portefaix, Bruno Ranchin, Choni Rinat, Adnan Safdar, Gesa Schalk, Poyyapakkam R. Srivaths, Cheryl L. Tran, William Van't Hoff, Jenny Weinbrand-Goichberg, Irith Weissman
Publikováno v:
Genetics in Medicine. 24:654-662
Primary hyperoxaluria type 1 (PH1) is a rare, progressive, genetic disease with limited treatment options. We report the efficacy and safety of lumasiran, an RNA interference therapeutic, in infants and young children with PH1.This single-arm, open-l
Autor:
John Lieske, Jaap Groothoff, Yaacov Frishberg, Anne-Laure Sellier-Leclerc, Hadas Shasha-Lavsky, Jeffrey Saland, Wesley Hayes, Daniella Magen, Shabbir Moochhala, Martin Coenen, Eva Simkova, Taylor Ngo, John Gansner, Sally-Anne Hulton
Publikováno v:
Journal of Urology. 207
Autor:
Maayan Kagan, Yishay Ben Moshe, Omer Shlomovitz, Danit Atias-Varon, Orly Haskin, Efrat Ben-Shalom, Daniella Magen, Ruth Schreiber, Oded Volovelsky, Hadas Shasha-Lavsky, Miriam Davidovits, Yael Borovitz, Nofar Mor, Yulia Khavkin, Shimrit Tzvi Behr, Shirley Pollack, Michael Geylis, Aviad Schnapp, Irith Weissman, Ortal Barel, Asaf Vivante
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND Chronic kidney disease in children is estimated to be secondary to a monogenic etiology in ∼20% of patients and can arise from mutations in a multitude of different single-gene causes. Still, data are lacking on the true prevalence of ge
Autor:
Jaap Groothoff, Mini Michael, Hadas Shasha-Lavsky, John Lieske, Yaacov Frishberg, Eva Simkova, Anne-Laure Sellier-Leclerc, Devresse Arnaud, Fitsum Guebre-Egziabher, Sevcan Azime Bakkaloglu, Chebl Mourani, Rola Saqan, Richard Singer, Richard Willey, Bahru Habtemariam, Ishir Bhan, John Gansner, Daniella Magen
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterised by hepatic oxalate overproduction that leads to progressive kidney disease. As kidney function declines, oxalate elimination is compromised and plasma oxa
Autor:
Pushkal Garg, William O'Riordan, Sally A. Hulton, John C. Lieske, Jaap W. Groothoff, Eva Simkova, Hadas Shasha-Lavsky, Sander F. Garrelfs, Akshay Vaishnaw, Gesa Schalk, John M. Gansner, Kristin Meliambro, Pierre Cochat, Daniella Magen, Daniel Guido Fuster, Marianne T. Sweetser, William van’t Hoff, Jiandong Lu, Michael J. Koren, Yaacov Frishberg, Jeffrey M. Saland, Shabbir H. Moochhala, Georges Deschênes, Tracy L. McGregor, David J. Sas
Publikováno v:
New England journal of medicine, 384(13), 1216-1226. Massachussetts Medical Society
Background: Primary hyperoxaluria type 1 (PH1) is a rare genetic disease caused by hepatic overproduction of oxalate that leads to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. Lumasiran, an investigational RNA interference
Publikováno v:
Harefuah. 160(12)
Hyperuricemia can cause renal damage and acute kidney injury or be secondary to renal failure and reduced excretion. Rasburicase, a recombinant urate oxidase, is a common treatment for hyperuricemia from different etiologies. There are scarce reports