Cell cycle oscillators underlying orderly proteolysis of E2F8

Autor: Evelin Sheinberger-Chorni, Meital Cohen, Roxane Lahmi, Sapir Nachum, Jasmin Parasol, Amit Tzur, Doron Gerber, Meirav Noach-Hirsh, Michael J. Emanuele, Xianxi Wang, Hadas Nevenzal, Efrat Michaely, Nofar Levi-Dadon, Taylor P. Enrico, Naomi Auerbach, Danit Wasserman, Sarit Zomer-Polak

Publikováno v: Molecular Biology of the Cell

E2F8 is a transcriptional repressor that antagonizes the canonical cell cycle transcription factor E2F1. Despite the importance of this atypical E2F family member in cell cycle, apoptosis and cancer, we lack a complete description of the mechanisms t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34a80b1fbbbf7ce485a1b8be9e52e7c
http://europepmc.org/articles/PMC7185961

Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa

Autor: Undine Mechold, Jacquelyn D. Rich, Yafit Yarmiyhu, Ehud Banin, Denice C. Bay, Volkhard Kaever, Dorit Cohen, Joe J. Harrison, Matthew R. Parsek, Trevor E. Randall, Hadas Nevenzal

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (36), pp.11359-64. ⟨10.1073/pnas.1421450112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (36), pp.11359-64. ⟨10.1073/pnas.1421450112⟩

International audience; The second messenger cyclic diguanylate (c-di-GMP) controls diverse cellular processes among bacteria. Diguanylate cyclases synthesize c-di-GMP, whereas it is degraded by c-di-GMP-specific phosphodiesterases (PDEs). Nearly 80%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a456ec295a4cf590e39efb681c1ea0
https://doi.org/10.1073/pnas.1421450112