Zobrazeno 1 - 3
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pro vyhledávání: '"Hadas Achildiev Cohen"'
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112238- (2023)
Summary: Depletion of Ca2+ from the endoplasmic reticulum (ER) causes the ER Ca2+ sensor STIM1 to form membrane contact sites (MCSs) with the plasma membrane (PM). At the ER-PM MCS, STIM1 binds to Orai channels to induce cellular Ca2+ entry. The prev
Externí odkaz:
https://doaj.org/article/a264906937de4dc982e3e3d6008193f1
Autor:
Ronald Udasin, Anwesha Sil, Elia Zomot, Hadas Achildiev Cohen, Jozafina Haj, Nurit Engelmayer, Shaya Lev, Alexander M. Binshtok, Yuval Shaked, Michael A. Kienzler, Raz Palty
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(13)
Significance Calcium release–activated calcium (CRAC) channels play key roles in the regulation of cellular signaling, transcription, and migration. Here, we describe the design, chemical synthesis, and characterization of photoswitchable channel i
Publikováno v:
Journal of Cell Biology. 220
Store-operated calcium entry (SOCE) through the Ca2+ release–activated Ca2+ (CRAC) channel is a central mechanism by which cells generate Ca2+ signals and mediate Ca2+-dependent gene expression. The molecular basis for CRAC channel regulation by th