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of 7
pro vyhledávání: '"Hadas, Han"'
Autor:
Emma Grabarnick (Portnoy), Alexander V. Andriyanov, Hadas Han, Sara Eyal, Yechezkel Barenholz
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2181 (2021)
Multidrug resistance (MDR) of cancer cells remains a major obstacle to favorable outcomes of treatment with many drugs, including doxorubicin. Most of the clinical trials failed to demonstrate the benefit of the drug efflux transporter P-glycoprotein
Externí odkaz:
https://doaj.org/article/eabeaa5a778f413688ce59b3a374319b
Autor:
Dana Blatch, Odeya Bennett, Aniv Mann Brukner, Sara Eyal, Sarah Billington, Mony Benifla, Yakov Fellig, Hadas Han, Olga Volkov, Dana Ekstein, Tot Bui Nguyen, Tal Gilboa, Jashvant D. Unadkat
Publikováno v:
Molecular Pharmaceutics. 18:2263-2273
Our goal was to measure the absolute differential abundance of key drug transporters in human epileptogenic brain tissue and to compare them between patients and at various distances from the epileptogenic zone within the same patient. Transporter pr
Monocytes as Carriers of Magnetic Nanoparticles for Tracking Inflammation in the Epileptic Rat Brain
Autor:
Dana Ekstein, Boris Polyak, Emma Portnoy, Mony Benifla, Aniv Mann, Sara Eyal, Hadas Han, Miriam Shmuel
Publikováno v:
Current Drug Delivery. 16:637-644
Background: Inflammation is a hallmark of epileptogenic brain tissue. Previously, we have shown that inflammation in epilepsy can be delineated using systemically-injected fluorescent and magnetite- laden nanoparticles. Suggested mechanisms included
Autor:
Aniv Mann, Brukner, Sarah, Billington, Mony, Benifla, Tot Bui, Nguyen, Hadas, Han, Odeya, Bennett, Tal, Gilboa, Dana, Blatch, Yakov, Fellig, Olga, Volkov, Jashvant D, Unadkat, Dana, Ekstein, Sara, Eyal
Publikováno v:
Molecular Pharmaceutics
Our goal was to measure the absolute differential abundance of key drug transporters in human epileptogenic brain tissue and to compare them between patients and at various distances from the epileptogenic zone within the same patient. Transporter pr
Autor:
Dana Blatch, Emma Portnoy, Miriam Shmuel, Sara Eyal, Tamir Ben-Hur, Hadas Han, Dana Ekstein, Aniv Mann, Dorrit Inbar
Publikováno v:
Epilepsy research. 142
Folate is involved in metabolic processes and it has been implicated in both aggravation and amelioration of seizures. The aim of the current work was to study the effect of chronic temporal lobe epilepsy (TLE) on the plasma and brain concentrations
Publikováno v:
The AAPS journal. 19(4)
Epilepsy is a neurological disease with variable etiology and clinical manifestation, affecting more than 50 million people worldwide. Although the ultimate precipitators of seizures are neurons, it is becoming evident that epileptic activity is asso
Publikováno v:
Clinical pharmacology and therapeutics. 100(5)
Molecular imaging allows noninvasive assessment of drug distribution across pharmacological barriers. Thus, it plays an increasingly important role in efforts to understand the interactions of molecules with membrane transporters during drug developm