Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Hada Buhe"'
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Pancreatic cancer (PC) is a fatal malignancy in the human abdominal cavity that prefers to invade the surrounding nerve/nerve plexus and even the spine, causing devastating and unbearable pain. The limitation of available in vitro models restricts re
Externí odkaz:
https://doaj.org/article/764320fa81794db78fbf363b0f1c650c
Autor:
Hada Buhe, Ji-xin Ma, Fang-zhou Ye, Chen-yun Song, Xin-yu Chen, Yang Liu, Huang Lin, Xu Han, Li-xiang Ma, Hexige Saiyin
Publikováno v:
Acta pharmacologica Sinica.
Neoplastic cells of non-immunogenic pancreatic ductal adenocarcinoma (PDAC) express indoleamine 2,3-dioxygenase 1 (IDO-1), an immunosuppressive enzyme. The metabolites of IDO-1 in cancers provide one-carbon units that annihilate effector T cells, and