β-glucans from Agaricus bisporus mushroom products drive Trained Immunity.

Autor: Case S; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., O'Brien T; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., Ledwith AE; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., Chen S; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin, Ireland., Horneck Johnston CJH; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., Hackett EE; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., O'Sullivan M; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., Charles-Messance H; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland., Dempsey E; School of Genetics and Microbiology, Trinity College, Dublin, Ireland., Yadav S; MBio, Monaghan, Ireland., Wilson J; MBio, Monaghan, Ireland., Corr SC; School of Genetics and Microbiology, Trinity College, Dublin, Ireland.; APC Microbiome Ireland, University College Cork, Cork, Ireland., Nagar S; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin, Ireland., Sheedy FJ; School of Biochemistry and Immunology, Trinity College, Dublin, Ireland.; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin, Ireland.

Publikováno v: Frontiers in nutrition [Front Nutr] 2024 Feb 15; Vol. 11, pp. 1346706. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).

Negative Regulation of Innate Immune Signaling by Components of the Button Mushroom Agaricus bisporus.

Autor: O'Sullivan M; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Dempsey E; School of Genetics & Microbiology, Trinity College, Dublin 2, D02 PN40, Ireland., Case S; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Hackett EE; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Ledwith AE; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Prendeville H; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., O'Brien T; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Lewis F; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Murphy DM; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland., Yadav S; MBio, Monaghan Mushrooms, Tyholland, Co. Monaghan, Monaghan, H18 FW95, Ireland., Wilson J; MBio, Monaghan Mushrooms, Tyholland, Co. Monaghan, Monaghan, H18 FW95, Ireland., Corr SC; School of Genetics & Microbiology, Trinity College, Dublin 2, D02 PN40, Ireland., Sheedy FJ; School of Biochemistry & Immunology, Trinity College, Dublin 2, D02 R590, Ireland.

Publikováno v: Molecular nutrition & food research [Mol Nutr Food Res] 2023 Jul; Vol. 67 (14), pp. e2200845. Date of Electronic Publication: 2023 Jun 06.

von Willebrand factor links primary hemostasis to innate immunity.

Autor: Drakeford C; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Aguila S; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland.; Centro Regional de Hemodonación, Hospital Universitario Morales Meseguer, IMIB-Arrixaca, Murcia, Spain., Roche F; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, College Green, Dublin, Ireland., Hokamp K; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, College Green, Dublin, Ireland., Fazavana J; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Cervantes MP; School of Pharmacy and Biomolecular Science (PBS) and Tissue Engineering Research Group (TERG), Royal College of Surgeons in Ireland, Dublin, 2, Ireland., Curtis AM; School of Pharmacy and Biomolecular Science (PBS) and Tissue Engineering Research Group (TERG), Royal College of Surgeons in Ireland, Dublin, 2, Ireland., Hawerkamp HC; School of Medicine, Trinity College Dublin, Dublin, 2, Ireland., Dhami SPS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Charles-Messance H; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Hackett EE; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Chion A; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Ward S; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Ahmad A; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Schoen I; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Breen E; Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Keane J; School of Medicine, Trinity College Dublin, Dublin, 2, Ireland., Murphy R; Department of Cardiology, St James's Hospital, Dublin, Ireland., Preston RJS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., O'Sullivan JM; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland., Sheedy FJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Fallon P; School of Medicine, Trinity College Dublin, Dublin, 2, Ireland.; Department of Cardiology, St James's Hospital, Dublin, Ireland., O'Donnell JS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Science (PBS), Royal College of Surgeons in Ireland, Dublin, Ireland. jamesodonnell@rcsi.ie.; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland. jamesodonnell@rcsi.ie.; National Coagulation Centre, St James's Hospital, Dublin, Ireland. jamesodonnell@rcsi.ie.

Publikováno v: Nature communications [Nat Commun] 2022 Nov 03; Vol. 13 (1), pp. 6320. Date of Electronic Publication: 2022 Nov 03.

An Army Marches on Its Stomach: Metabolic Intermediates as Antimicrobial Mediators in Mycobacterium tuberculosis Infection.

Autor: Hackett EE; Macrophage Homeostasis, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Sheedy FJ; Macrophage Homeostasis, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2020 Aug 25; Vol. 10, pp. 446. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).

Leading-edge vortices over swept-back wings with varying sweep geometries.

Autor: Lambert WB; Department of Math, Computer Science, and Physics, Roanoke College, Salem, VA, USA., Stanek MJ; Department of Coastal and Marine Systems Science, Coastal Carolina University, Conway, SC, USA., Gurka R; Department of Coastal and Marine Systems Science, Coastal Carolina University, Conway, SC, USA., Hackett EE; Department of Coastal and Marine Systems Science, Coastal Carolina University, Conway, SC, USA.

Publikováno v: Royal Society open science [R Soc Open Sci] 2019 Jul 10; Vol. 6 (7), pp. 190514. Date of Electronic Publication: 2019 Jul 10 (Print Publication: 2019).