Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Hachiro Inokuchi"'
Autor:
Hachiro Inokuchi
Publikováno v:
Genesgenomics. 44(11)
The question of whether the coronavirus genome contain as-yetununderstood genetic component.Elucidate the novel functions of the discovered tRNA-like base sequence and lead to the development of novel therapeutic agents.A novel tRNA-like base sequenc
Publikováno v:
Journal of Biological Chemistry. 288:32952-32962
In aerobically growing cells, in which reactive oxygen species are produced, the guanine base is oxidized to 8-oxo-7,8-dihydroguanine, which can pair with adenine as well as cytosine. This mispairing causes alterations in gene expression, and cells p
Autor:
Akio Kanai, Akira Muto, Toshimichi Ikemura, Hachiro Inokuchi, Takashi Abe, Yasuo Ohara, Yuko Yamada, Hiroshi Uehara, Makoto Kinouchi, Junichi Sugahara, Shigehiko Kanaya
Publikováno v:
Nucleic Acids Research
We updated the tRNADB-CE by analyzing 939 complete and 1301 draft genomes of prokaryotes and eukaryotes, 171 complete virus genomes, 121 complete chloroplast genomes and approximately 230 million sequences obtained by metagenome analyses of 210 envir
Publikováno v:
Molecular Microbiology. 54:1011-1021
Summary The post-termination ribosomal complex is disassembled by ribosome recycling factor (RRF) and elongation factor G. Without RRF, the ribosome is not released from mRNA at the termination codon and reinitiates translation downstream. This is ca
Publikováno v:
Journal of Bacteriology. 185:1726-1729
According to the wobble rule, tRNA2Thr is nonessential for protein synthesis, because the codon (ACG) that is recognized by tRNA2Thr is also recognized by tRNA4Thr. In order to investigate the reason that this nonessential tRNA nevertheless exists in
Autor:
Toshihiro Ansai, Sumio Akifusa, Kenji Nakahigashi, Tadamichi Takehara, Hachiro Inokuchi, Akito Kusaba
Publikováno v:
DNA Sequence. 14:71-74
HemK, a universally conserved protein of unknown function, has high amino acid similarity with DNA-(adenine- N6 ) methyltransferases (MTases). In the present study, we sequenced a 5026 bp DNA fragment just downstream of the PgPepO gene reported previ
Autor:
Wolf-Dieter Schubert, Lennart Randau, Stefan Lorenz, Stefan Schauer, Dirk W. Heinz, Hans-Ulrich Thomann, Masatoshi Murai, Jürgen Moser, Dieter Jahn, Elizabeth Verkamp, Hachiro Inokuchi, Makoto Kitabatake, Shalini Chaturvedi, Dieter Söll, Toru Nakayashiki, Kristen Wall
Publikováno v:
Journal of Biological Chemistry. 277:48657-48663
In the first step of tetrapyrrole biosynthesis inEscherichia coli, glutamyl-tRNA reductase (GluTR, encoded by hemA) catalyzes the NADPH-dependent reduction of glutamyl-tRNA to glutamate-1-semialdehyde. Soluble homodimeric E. coli GluTR was made by co
Publikováno v:
International Congress Series. 1233:51-57
The heme molecule plays an important role in the electron transfer performed by redox proteins such as cytochromes. In addition, it has been suggested that heme has a structural role in protein folding and assembly. However, it is now known that prot
Autor:
Yosuke Suzuki, Mahito Nakanishi, Emi Nagoshi, Hiroyuki Mizuguchi, Hajime Okuyama, Akiko Eguchi, Mamoru Hasegawa, Teruo Akuta, Takao Senda, Takao Hayakawa, Hachiro Inokuchi, Katsuo Takeda
Publikováno v:
Biochemical and Biophysical Research Communications. 297:779-786
The cell membrane and the nuclear membrane are two major barriers hindering the free movement of various macromolecules through animal cells. Nevertheless, some proteins can actively bypass these barriers by dint of intrinsic peptidic signals, so inc