Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake.

Autor: Habtemichael EN; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Evelo Biosciences, Inc., Cambridge, MA, USA., Li DT; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA., Camporez JP; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; University of São Paulo, São Paulo, Brazil., Westergaard XO; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Columbia University, New York, NY, USA., Sales CI; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Liu X; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA., López-Giráldez F; Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT, USA., DeVries SG; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Li H; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Zhejiang University of Technology, Hangzhou, China., Ruiz DM; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Wang KY; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Sayal BS; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., González Zapata S; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Dann P; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Brown SN; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Hirabara S; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Institute of Physical Activity Sciences and Sports, Cruzeiro do Sul University, São Paulo, Brazil., Vatner DF; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Goedeke L; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Philbrick W; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Shulman GI; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA., Bogan JS; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA. jonathan.bogan@yale.edu.; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA. jonathan.bogan@yale.edu.

Publikováno v: Nature metabolism [Nat Metab] 2021 Mar; Vol. 3 (3), pp. 378-393. Date of Electronic Publication: 2021 Mar 08.

GLUT4 Storage Vesicles: Specialized Organelles for Regulated Trafficking.

Autor: Li DT; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT.; Department of Cell Biology, Yale University School of Medicine, Yale University, New Haven, CT., Habtemichael EN; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Julca O; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Sales CI; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Westergaard XO; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., DeVries SG; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Ruiz D; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Sayal B; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT., Bogan JS; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT.; Department of Cell Biology, Yale University School of Medicine, Yale University, New Haven, CT.

Publikováno v: The Yale journal of biology and medicine [Yale J Biol Med] 2019 Sep 20; Vol. 92 (3), pp. 453-470. Date of Electronic Publication: 2019 Sep 20 (Print Publication: 2019).

Rab14 limits the sorting of Glut4 from endosomes into insulin-sensitive regulated secretory compartments in adipocytes.

Autor: Brewer PD; Department of Biochemistry and Molecular Biology, and Department of Pharmacology, University of Nevada, Reno, NV 89557, U.S.A., Habtemichael EN; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, U.S.A., Romenskaia I; Department of Biochemistry and Molecular Biology, and Department of Pharmacology, University of Nevada, Reno, NV 89557, U.S.A., Coster AC; Department of Applied Mathematics, School of Mathematics and Statistics, University of New South Wales, Sydney 2052, Australia., Mastick CC; Department of Biochemistry and Molecular Biology, and Department of Pharmacology, University of Nevada, Reno, NV 89557, U.S.A. cmastick@unr.edu.

Publikováno v: The Biochemical journal [Biochem J] 2016 May 15; Vol. 473 (10), pp. 1315-27. Date of Electronic Publication: 2016 Mar 02.

Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle.

Autor: Habtemichael EN; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and., Alcázar-Román A; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and., Rubin BR; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8020., Grossi LR; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8020., Belman JP; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8020., Julca O; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8020., Löffler MG; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and., Li H; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and., Chi NW; the Veterans Affairs San Diego Healthcare System and Department of Medicine, University of California, San Diego, California 92093, and., Samuel VT; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and the Veterans Affairs Medical Center, West Haven, Connecticut 06516., Bogan JS; From the Section of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8020, jonathan.bogan@yale.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2015 Jun 05; Vol. 290 (23), pp. 14454-61. Date of Electronic Publication: 2015 May 05.

Insulin-regulated Glut4 translocation: membrane protein trafficking with six distinctive steps.

Autor: Brewer PD; From the Department of Biochemistry and Molecular Biology, University of Nevada School of Medicine, Reno, Nevada 89557., Habtemichael EN; the Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, and., Romenskaia I; From the Department of Biochemistry and Molecular Biology, University of Nevada School of Medicine, Reno, Nevada 89557., Mastick CC; From the Department of Biochemistry and Molecular Biology, University of Nevada School of Medicine, Reno, Nevada 89557, cmastick@unr.edu., Coster AC; the School of Mathematics and Statistics, University of New South Wales, Sydney, New South Wales 2052, Australia.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2014 Jun 20; Vol. 289 (25), pp. 17280-98. Date of Electronic Publication: 2014 Apr 28.