Multitarget Fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage

Autor: Sasso, O, Migliore, M, Habrant, D, Armirotti, A, Albani, C, Summa, M, Moreno-Sanz, G, Scarpelli, R, Piomelli, D

Publikováno v: Sasso, O; Migliore, M; Habrant, D; Armirotti, A; Albani, C; Summa, M; et al.(2015). Multitarget Fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage. FASEB Journal, 29(6), 2616-2627. doi: 10.1096/fj.15-270637. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/38h4c96x

© FASEB. Theabilityofnonsteroidal anti-inflammatory drugs (NSAIDs) to inhibit cyclooxygenase (Cox)-1 and Cox-2 underlies the therapeutic efficacy of these drugs, as well as their propensity to damage the gastrointestinal (GI) epithelium. This toxic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::853a62b73ed096346b360437225debb0
http://www.escholarship.org/uc/item/38h4c96x

Design of Ionizable Lipids To Overcome the Limiting Step of Endosomal Escape: Application in the Intracellular Delivery of mRNA, DNA, and siRNA

Autor: HABRANT, D., PEUZIAT, P., COLOMBANI, T., DALLET, L., GEHIN, J., GOUDEAU, E., EVRARD, B., LAMBERT, O., HAUDEBOURG, T., PITARD, B.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______9631::407daf9871dda764bc1df97c82c62567
http://hdl.handle.net/20.500.12278/10865

Supramolecular Gene Transfection Agents

Autor: Pitard, B.., Habrant, D..

Publikováno v: In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering 2013

Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction.

Autor: Bhosle SM; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Loomis KH; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Kirschman JL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Blanchard EL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Vanover DA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA., Habrant D; In-Cell-Art, 21 rue de la Noue Bras de Fer, 44200, Nantes, France., Edwards D; Sanofi Pasteur, VaxDesign Corporation, 2501 Discovery Dr Suite 300, Orlando, FL, 32826, USA., Baumhof P; CureVac AG, Paul-Ehrlich-Str. 15, 72076, Tübingen, Germany., Pitard B; In-Cell-Art, 21 rue de la Noue Bras de Fer, 44200, Nantes, France. Electronic address: bruno.pitard@incellart.com., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Dr. NW, Engineered Biosystems Building, Atlanta, GA, 30332, USA. Electronic address: philip.santangelo@bme.gatech.edu.

Publikováno v: Biomaterials [Biomaterials] 2018 Mar; Vol. 159, pp. 189-203. Date of Electronic Publication: 2018 Jan 06.

Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery.

Autor: Colombani T; CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France., Peuziat P; CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France., Dallet L; CBMN UMR-CNRS 5248, Université de Bordeaux IPB, Pessac, France., Haudebourg T; CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France., Mével M; CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France., Berchel M; UMR CNRS 6521, IFR 148 ScInBioS, Université de Bretagne Occidentale, Université Européenne de Bretagne, Brest, France., Lambert O; CBMN UMR-CNRS 5248, Université de Bordeaux IPB, Pessac, France., Habrant D; In-Cell-Art, Nantes, France., Pitard B; CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France; In-Cell-Art, Nantes, France. Electronic address: bruno.pitard@univ-nantes.fr.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2017 Mar 10; Vol. 249, pp. 131-142. Date of Electronic Publication: 2017 Feb 01.