Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Habib A M, Sakil"'
Autor:
Johanna, Wolfsberger, Habib A M, Sakil, Leilei, Zhou, Niek, van Bree, Elena, Baldisseri, Sabrina, de Souza Ferreira, Veronica, Zubillaga, Marina, Stantic, Nicolas, Fritz, Johan, Hartman, Charlotte, Rolny, Margareta T, Wilhelm
Publikováno v:
Proc Natl Acad Sci U S A
Infiltration of tumor-promoting immune cells is a strong driver of tumor progression. Especially the accumulation of macrophages in the tumor microenvironment is known to facilitate tumor growth and to correlate with poor prognosis in many tumor type
Publikováno v:
Oncogene
Cellular responses to low oxygen conditions are mainly regulated by the Hypoxia-inducible factors (HIFs). Induction of HIF-1α in tumor cells activates the angiogenic switch and allows for metabolic adaptations. HIF-1α protein levels are tightly reg
Autor:
Johanna Wolfsberger, Habib A. M. Sakil, Margareta Wilhelm, Johan Hansson, Marina Stantic, Suzanne Egyhazi Brage
Publikováno v:
Cellular Oncology (Dordrecht)
Purpose Multidrug resistance (MDR) is a major cause of treatment failure. In cancer cells, MDR is often caused by an increased efflux of therapeutic drugs mediated by an up-regulation of ATP binding cassette (ABC) transporters. It has previously been
Autor:
Marina Stantic, Tak W. Mak, Evelyn Susanto, Margareta Wilhelm, Ana Marin, Marie Henriksson, Trixy Fang, Habib A. M. Sakil, Hanna Zirath, Alejandro Fernandez-Woodbridge, Gema Sanz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(1)
The p53-family member TAp73 is known to function as a tumor suppressor and regulates genomic integrity, cellular proliferation, and apoptosis; however, its role in tumor angiogenesis is poorly understood. Here we demonstrate that TAp73 regulates tumo