Výsledky vyhledávání - "Habib, Karoui"

Akademický článek

Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells

Autor: Manel B. Hammouda, María F. Montenegro, Luis Sánchez-del-Campo, Ons Zakraoui, Zohra Aloui, Ichrak Riahi-Chebbi, Habib Karoui, José Neptuno Rodríguez-López, Khadija Essafi-Benkhadir

Publikováno v: Toxins, Vol 8, Iss 7, p 206 (2016)

Melanoma, the most threatening form of skin cancer, has a very poor prognosis and is characterized by its very invasive and chemoresistant properties. Despite the recent promising news from the field of immunotherapy, there is an urgent need for new

Externí odkaz: https://doaj.org/article/3cf95e28d7d44555be6407b0f775fea5

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Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin

Autor: Habib Karoui, Kenneth J. Clemetson, Timothy N. C. Wells, Houcemeddine Othman, Soumaya Souid, José Neptuno Rodríguez-López, Ichrak Riahi-Chebbi, Zohra Aloui, Ammar Gasmi, Edith M. Magnenat, Najet Srairi-Abid, Khadija Essafi-Benkhadir, Manel B Hammouda

Publikováno v: Biochimica et Biophysica Acta (BBA)-General Subjects
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2018, 1862 (3), pp.600--614. ⟨10.1016/j.bbagen.2017.11.019⟩

Background The resistance of melanoma cells to cisplatin restricts its clinical use. Therefore, the search for novel tumor inhibitors and effective combination treatments that sensitize tumor cells to this drug are still needed. We purified macrovipe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f1c617f4ea3f5dfa760615b6a3fee6
https://doi.org/10.1016/j.bbagen.2017.11.019

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The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

Autor: Houcemeddine Othman, Ichrak Riahi-Chebbi, Meriam Haoues, Soumaya Souid, Makram Essafi, Habib Karoui, Alain Morel, Najet Srairi-Abid, Khadija Essafi-Benkhadir

Publikováno v: Scientific Reports
Scientific Reports, 2019, 9 (1), pp.195. ⟨10.1038/s41598-018-36808-z⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.195. ⟨10.1038/s41598-018-36808-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-018-36808-z⟩

International audience; Resistance to 5-Fluorouracil chemotherapy is a major cause of therapeutic failure in colon cancer cure. Development of combined therapies constitutes an effective strategy to inhibit cancer cells and prevent the emergence of d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe4d305a6ceab17fdce5c982785b621
https://www.hal.inserm.fr/inserm-02097051

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Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Autor: Ammar Gasmi, Houcemeddine Othman, Makram Essafi, Renaud Grépin, Meriam Haoues, Najet Srairi-Abid, Gilles Pagès, Habib Karoui, Khadija Essafi-Benkhadir, Ons Zakraoui, Zohra Aloui, Cezary Marcinkiewicz

Publikováno v: Molecular Carcinogenesis. 56:18-35

Lebein, is an heterodimeric disintegrin isolated from Macrovipera lebetina snake venom that was previously characterized as an inhibitor of ADP-induced platelet aggregation. In this study, we investigated the effect of Lebein on the p53-dependent gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0585f28438d7476124d0d6c1804ac8fb
https://doi.org/10.1002/mc.22470

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131 -Oxophorbine protopheophorbide A from Ziziphus lotus as a novel mesenchymal-epithelial transition factor receptor inhibitory lead for the control of breast tumor growth in vitro and in vivo

Autor: Khalid A. El Sayed, Mohamed M. Mohyeldin, Khadija Essafi-Benkhadir, Habib Karoui, Heba E. Elsayed, Abu Bakar Siddique, Soumaya Souid, Hassan Y. Ebrahim

Publikováno v: Molecular Carcinogenesis
Molecular Carcinogenesis, Wiley, 2018, ⟨10.1002/mc.22874⟩

International audience; The failure of chemotherapy especially in triple negative breast cancer (TNBC) patients has been correlated with the overexpression of the mesenchymal-epithelial transition factor (c-Met) receptor. Thus, the hepatocyte growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896e4061f5bfda2fcf53ca50b8392d86
https://hal.archives-ouvertes.fr/hal-01873762

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Allium Roseum L. Extract Exerts Potent Suppressive Activities on Chronic Myeloid Leukemia K562 Cell Viability Through the Inhibition of BCR-ABL, PI3K/Akt, and ERK

Autor: Soumaya, Souid, Hanen, Najjaa, Ichrak, Riahi-Chebbi, Meriam, Haoues, Mohamed, Neffati, Ingrid, Arnault, Jacques, Auger, Habib, Karoui, Makram, Essafi, Khadija, Essafi-Benkhadir

Publikováno v: Nutrition and cancer. 69(1)

Use of plant extracts, alone or combined to the current chemotherapy as chemosensitizers, has emerged as a promising strategy to overcome tumor drug resistance. Here, we investigated the anticancer activity of Allium roseum L. extracts, a wild edible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a681590a9c301c8550548f43f124044
https://pubmed.ncbi.nlm.nih.gov/27892697

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Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells

Autor: Zohra Aloui, Khadija Essafi-Benkhadir, Ons Zakraoui, María F. Montenegro, Luis Sánchez-del-Campo, Habib Karoui, Manel B Hammouda, José Neptuno Rodríguez-López, Ichrak Riahi-Chebbi

Publikováno v: Toxins
Toxins, MDPI, 2016, 8 (7), ⟨10.3390/toxins8070206⟩
Toxins, Vol 8, Iss 7, p 206 (2016)
Toxins; Volume 8; Issue 7; Pages: 206

International audience; Melanoma, the most threatening form of skin cancer, has a very poor prognosis and is characterized by its very invasive and chemoresistant properties. Despite the recent promising news from the field of immunotherapy, there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6131337b2f67da725134d6ad57d726a
https://hal-riip.archives-ouvertes.fr/pasteur-01374990

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Asteraceae

Autor: Zohra, Aloui, Chokri, Messaoud, Meriam, Haoues, Noura, Neffati, Imen, Bassoumi Jamoussi, Khadija, Essafi-Benkhadir, Mohamed, Boussaid, Ikram, Guizani, Habib, Karoui

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM

We report the chemical composition and anti-Leishmania and antioxidant activity of Artemisia campestris L. and Artemisia herba-alba Asso. essential oils (EOs). Our results showed that these extracts exhibit different antioxidant activities according

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed247ead848b82e5933cd725e5fbac85
https://pubmed.ncbi.nlm.nih.gov/27807464

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Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Autor: Ons, Zakraoui, Cezary, Marcinkiewicz, Zohra, Aloui, Houcemeddine, Othman, Renaud, Grépin, Meriam, Haoues, Makram, Essafi, Najet, Srairi-Abid, Ammar, Gasmi, Habib, Karoui, Gilles, Pagès, Khadija, Essafi-Benkhadir

Publikováno v: Molecular Carcinogenesis
Molecular Carcinogenesis, Wiley, 2016, 56, pp.18-35. ⟨10.1002/mc.22470⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0f26039872eae3cfc403bba0d6257ac7
https://hal.archives-ouvertes.fr/hal-01356511

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Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy

Autor: Sami Fattouch, Ichrak Riahi-Chebbi, Meriam Haoues, Makram Essafi, Khadija Essafi-Benkhadir, Habib Karoui, Ons Zakraoui

Publikováno v: Cancer Cell International
Cancer Cell International, BioMed Central, 2015, 16 (1), pp.1. ⟨10.1186/s12935-016-0276-7⟩

Background Development of alternative cancer-specific drugs would be of paramount importance to overcome toxicity toward normal tissues and tumor resistance. Here, we investigated the potential anti-tumoral effect of peel (Peph) and pulp polyphenolic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e264b17c7ccade0174c06068a53357
https://doi.org/10.1186/s12935-016-0276-7

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