Sulfated Glycoaminoglycans and Proteoglycan Syndecan-4 Are Involved in Membrane Fixation of LL-37 and Its Pro-Migratory Effect in Breast Cancer Cells

Autor: Habes, Chahrazed, Weber, Günther, Goupille, Caroline

Publikováno v: Biomolecules
Volume 9
Issue 9
Biomolecules, Vol 9, Iss 9, p 481 (2019)
Biomolecules, MDPI, 2019, 9 (9), pp.481. ⟨10.3390/biom9090481⟩
Biomolecules, 2019, 9 (9), pp.481. ⟨10.3390/biom9090481⟩

Initially characterized by its antimicrobial activities, LL-37 has also been shown to significantly contribute to tumor development. On breast cancer cell lines, LL-37 increases intracellular calcium via the TRPV2 channel and their migration via the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::54582753e48c54ae0c6c168926a703b9
http://europepmc.org/articles/PMC6769752