Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Haas, Gerard H. de"'
1
CRYSTAL-STRUCTURE OF A PORCINE PANCREATIC PHOSPHOLIPASE-A2 MUTANT - A LARGE CONFORMATIONAL CHANGE CAUSED BY THE F63V POINT MUTATION
Autor: Thunnissen, Marjolein M.G.M., Franken, Peet A., Haas, Gerard H. de, Drenth, Jan, Kalk, Kor H., Verheij, Hubertus M., Dijkstra, Bauke W.
Publikováno v: Journal of Molecular Biology, 232(3), 839-855. Academic Press
The highly homologous bovine and porcine pancreatic phospholipases A2 (85% amino acid residue identity) show a large conformational difference in the loop from residue 59 to 71. In bovine phospholipase A2 residues 59 to 66 adopt an α-helix conformat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::3bb4be0ab7464f0470619342ea301305
https://research.rug.nl/en/publications/bf78d12e-4da1-480c-8db2-9108e47fcbcc
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3
Evidence that the zymogen of phospholipase A2 binds to a negatively charged lipid-water interface
Autor: Volwerk, J.J., Jost, P.C., Haas, Gerard H. de, Griffith, O.H.
Publikováno v: Chemistry and Physics of Lipids, 36(2), 101. Elsevier
Evidence is presented that the zymogen of porcine pancreatic phospholipase A2 (prophospholipase A2) interacts with a lipid-water interface provided that the interface has a net negative surface charge. Fluorescence spectroscopy and non-equilibrium ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9f83b9f23696b1002ece45bd2c0b5351
https://dspace.library.uu.nl/handle/1874/16352
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8
Hydrolysis of synthetic mixed-acid phosphatides by phospholipase A from human pancreas
Autor: Deenen, L.L.M. van, Haas, Gerard H. de, Heemskerk, C.H.Th.
Publikováno v: Biochimica et Biophysica Acta (BBA)-Specialized Section on Enzymological Subjects, 67, 295. Elsevier
An investigation was made into the action of a human pancreatic phospholipase A on various synthetic phosphatides. L-α-Phosphatidyl ethanolamines were readily hydrolysed in an aqueous system by this enzyme. Synthetic lecithins, however, were not att
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::572a45dbacea27df6f7f5d3b1e59a734
https://dspace.library.uu.nl/handle/1874/17878
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9
Silver di-t-butyl phosphate, a useful reagent in the synthesis of phospholipids. Synthesis of mixed-acid phosphatidic acid and phosphatidyl glycerolphosphate
Autor: Bonsen, P.P.M., Haas, Gerard H. de
Publikováno v: Chemistry and Physics of Lipids, 1(2), 100. Elsevier
The synthesis of silver di-t-butyl phosphate is described. Using this reagent, mixed-acid phosphatidic acid with one unsaturated fatty acid could be prepared by means of a reaction with a 1,2-diacyl glycerol-3-iodohydrin. The blocking groups could be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::42e910ef6605f84948f2032019da13d2
https://dspace.library.uu.nl/handle/1874/15883
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