Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Haakon Blakli"'
Autor:
Robert W. Allcock, Yasushi Kohno, David R. Adams, Keith M. Morgan, Ian D. Collier, Patrick D. Bailey, Georgina M. Rosair, Karen A. Johnston, Haakon Blakli, Zhong Jiang
Publikováno v:
Org. Biomol. Chem.. 6:175-186
Cycloaddition of pyridine N-imine with 6-alkyl-4-oxohex-5-ynoates followed by condensation with hydrazine provides concise access to pharmacologically active 6-(pyrazolo[1,5-a]pyridin-3-yl)pyridazinones. For the first time alkynyl heterocycles are al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a222786961860dcb76d2e5c5caffbed0
https://doi.org/10.1039/b713638b
https://doi.org/10.1039/b713638b
Autor:
Yasushi Kohno, Karen A. Johnston, Robert W. Allcock, Keith M. Morgan, Georgina M. Rosair, Zhong Jiang, David R. Adams, Kazuhiko Iwase, Haakon Blakli
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(11)
Ibudilast [1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one] is a nonselective phosphodiesterase inhibitor used clinically to treat asthma. Efforts to selectively develop the PDE3- and PDE4-inhibitory activity of ibudilast led to repla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a5bfd5255da6b3846203b01a70347d
https://pubmed.ncbi.nlm.nih.gov/21530250
https://pubmed.ncbi.nlm.nih.gov/21530250
Autor:
Keith M. Morgan, Ian D. Collier, Haakon Blakli, Robert W. Allcock, Zhong Jiang, Patrick D. Bailey, David R. Adams, Karen A. Johnston, Yasushi Kohno, Georgina M. Rosair
Publikováno v:
ChemInform. 39
Cycloaddition of pyridine N-imine with 6-alkyl-4-oxohex-5-ynoates followed by condensation with hydrazine provides concise access to pharmacologically active 6-(pyrazolo[1,5-a]pyridin-3-yl)pyridazinones. For the first time alkynyl heterocycles are al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae84fff6e7c878b125d693ba5098333
https://doi.org/10.1002/chin.200823148
https://doi.org/10.1002/chin.200823148