Supplementary Figures and Tables from Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells

Autor: Bruno Silva-Santos, David Vermijlen, Sarina Ravens, Haakan Norell, Immo Prinz, Ton N. Schumacher, Julie Déchanet-Merville, Maria Gomes da Silva, Tânia Carvalho, Daniel V. Correia, Paola Tieppo, Francisco Caiado, André E. Simões, Biagio Di Lorenzo

Supplementary Figures 1-5 and tables 1-3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7a03a36074149a2e97db6d339f277d
https://doi.org/10.1158/2326-6066.22542651

Supplementary Figures 1-6 from Low-Density Lipoprotein Uptake Inhibits the Activation and Antitumor Functions of Human Vγ9Vδ2 T Cells

Autor: Sérgio Dias, Bruno Silva-Santos, Haakan Norell, Adrian C. Hayday, Andrew Tutt, Fernanda Kyle-Cezar, Ana deBarros, Sandrina Nóbrega-Pereira, Sofia Mensurado, Daniel V. Correia, Neidy V. Rodrigues

S1. LDL-cholesterol does not affect the viability of human γÎ' T cells. S2. Effects of LDL-cholesterol on Vï�¤2+ T cells after 36 or 48 hours of culture. S3. Effects of LDL-cholesterol on additional immune functions of γÎ' T cells. S4. Ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ece802a27296fe67f38dfb3444c435f
https://doi.org/10.1158/2326-6066.22539205

Supplementary Methods from Off-Target Function of the Sonic Hedgehog Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide–Dependent Neutral Sphingomyelinase 2/Ceramide Induction

Autor: Besim Ogretmen, M. Ozgur Cevik, Monzur Murshed, Zohreh Khavandgar, Jacqueline M. Kraveka, Michael Nishimura, Telma Martins da Palma, Haakan Norell, Yusuf A. Hannun, Christopher J. Clarke, Sahar A. Saddoughi, R. David Sentelle, Salih Gencer, Jocelyn A. Lewis, Marisa Meyers-Needham

PDF file, 101KB.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed53ace47377516634066f230601f43
https://doi.org/10.1158/1535-7163.22498864.v1

Supplementary Figure S1, S2, S3, S4, S5 and S6. Supplementary Tables S1 and S2. from VEGFR2–Mediated Reprogramming of Mitochondrial Metabolism Regulates the Sensitivity of Acute Myeloid Leukemia to Chemotherapy

Autor: Sérgio Dias, Haakan Norell, Bruno Silva-Santos, Luís G. Gonçalves, Gonçalo Graça, Inês Matias, Tânia Carvalho, Francisco Caiado, Sandrina Nóbrega-Pereira

Supplementary Material and Methods. Supplementary Fig. S1. Additional characterization of in vivo chemotherapy treatment of human AML xenotransplanted mice and metabolic characterization of chemotherapy exposed human AML cells. Supplementary Fig. S2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56a5dbb5449fe934bb4e15055c54a89
https://doi.org/10.1158/0008-5472.22417557.v1

Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells

Autor: David Vermijlen, Bruno Silva-Santos, Biagio Di Lorenzo, Paola Tieppo, Maria Gomes da Silva, Immo Prinz, Tânia Carvalho, Sarina Ravens, Daniel V. Correia, André E. Simões, Francisco Caiado, T.N. Schumacher, Haakan Norell, Julie Déchanet-Merville

Publikováno v: Cancer Immunology Research
Cancer Immunology Research, American Association for Cancer Research, 2019, 7 (4), pp.552-558. ⟨10.1158/2326-6066.CIR-18-0647⟩
Cancer immunology research, 7 (4
Cancer Immunology Research, 2019, 7 (4), pp.552-558. ⟨10.1158/2326-6066.CIR-18-0647⟩

Acute myeloid leukemia (AML) remains a clinical challenge due to frequent chemotherapy resistance and deadly relapses. We are exploring the immunotherapeutic potential of peripheral blood Vd1 þ T cells, which associate with improved long-term surviv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f1065c4dcc78278cfd37062c3b0b9d
https://doi.org/10.1158/2326-6066.cir-18-0647