Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ha-Na Shim"'
Autor:
Chitavi D. Maulloo, Shijie Cao, Elyse A. Watkins, Michal M. Raczy, Ani. S. Solanki, Mindy Nguyen, Joseph W. Reda, Ha-Na Shim, D. Scott Wilson, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inverse vaccines that tolerogenically target antigens to antigen-presenting cells (APCs) offer promise in prevention of immunity to allergens and protein drugs and treatment of autoimmunity. We have previously shown that targeting hepatic APCs throug
Externí odkaz:
https://doaj.org/article/99a335f0b63f44b78429ca41ed9d3d85
Autor:
Pierre De Rossi, Toshihiro Nomura, Robert J. Andrew, Nicolas Y. Masse, Vandana Sampathkumar, Timothy F. Musial, Ari Sudwarts, Aleksandra J. Recupero, Thomas Le Metayer, Mitchell T. Hansen, Ha-Na Shim, Sofia V. Krause, David J. Freedman, Vytas P. Bindokas, Narayanan Kasthuri, Daniel A. Nicholson, Anis Contractor, Gopal Thinakaran
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
Summary: BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in
Externí odkaz:
https://doaj.org/article/3ee20aa26dbb4398a318c588047a8aa8
Autor:
Shijie Cao, Chitavi D. Maulloo, Michal M. Raczy, Matthew Sabados, Anna J. Slezak, Mindy Nguyen, Ani Solanki, Rachel P. Wallace, Ha-Na Shim, D. Scott Wilson, Jeffrey A. Hubbell
SummaryThe only FDA-approved oral immunotherapy for a food allergy provides protection against accidental exposure to peanuts. However, this therapy often causes discomfort or side effects and requires long-term commitment. Better preventive and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::353181093a4aa70ca3e902f3ae4e3d91
https://doi.org/10.1101/2023.03.23.534004
https://doi.org/10.1101/2023.03.23.534004
Autor:
Michael JV White, Michal M Raczy, Erica Budina, Eiji Yuba, Ani Solanki, Ha-Na Shim, Zheng Jenny Zhang, Laura T Gray, Shijie Cao, Aaron T. Alpar, Jeffrey A Hubbell
Fibrotic diseases are involved in 45% of deaths in the United States. In particular, fibrosis of the kidney and lung are major public health concerns due to their high prevalence and lack of existing treatment options. Here, we harness the pathophysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::734a3ff69ce0ee2c4d786bfd0673321c
https://doi.org/10.1101/2022.01.04.474747
https://doi.org/10.1101/2022.01.04.474747
Autor:
Michael White, Michal M. Raczy, Erica Budina, Eiji Yuba, Ani Solanki, Ha-Na Shim, Zheng Jenny Zhang, Laura T. Gray, Shijie Cao, Aaron T. Alpar, Jeffrey A. Hubbell
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04af1fb3f023098287646359eefc0c43
https://doi.org/10.2139/ssrn.4163649
https://doi.org/10.2139/ssrn.4163649
Autor:
Reid W. D’Amico, Shannon Faley, Ha-na Shim, Joanna R. Prosser, Vineet Agrawal, Leon M. Bellan, James D. West
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2561 (2018)
Endothelial dysfunction is a known consequence of bone morphogenetic protein type II receptor (BMPR2) mutations seen in pulmonary arterial hypertension (PAH). However, standard 2D cell culture models fail to mimic the mechanical environment seen in t
Externí odkaz:
https://doaj.org/article/47fbbf89b5b1474bb6d3b5367df35dfa
Autor:
Philip J. Kingsley, Thomas R. Blackwell, Lawrence J. Marnett, Ha-Na Shim, James J. Galligan, William D Sanders, Thong Luong, Mark deCaestecker, Jeannie M. Camarillo, William N. Beavers, Orrette R. Wauchope, Michelle M. Mitchener, Joshua P. Fessel
Publikováno v:
Nucleic Acids Research
Reactive oxygen species (ROS) are formed in mitochondria during electron transport and energy generation. Elevated levels of ROS lead to increased amounts of mitochondrial DNA (mtDNA) damage. We report that levels of M1dG, a major endogenous peroxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b5c891e8f51acd5d59e89ac1ddeb96
http://europepmc.org/articles/PMC5909422
http://europepmc.org/articles/PMC5909422
Autor:
Narayanan Kasthuri, Robert J. Andrew, Thomas Le Metayer, Vytas P. Bindokas, Ha Na Shim, Gopal Thinakaran, Sofia V. Krause, David J. Freedman, Mitchell T. Hansen, Vandana Sampathkumar, Daniel A. Nicholson, Ari Sudwarts, Anis Contractor, Nicolas Y. Masse, Timothy F. Musial, Toshihiro Nomura, Pierre De Rossi, Aleksandra J. Recupero
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
SUMMARY BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7407a457ffe8338cd75b9c89496a8d
https://pubmed.ncbi.nlm.nih.gov/32160554
https://pubmed.ncbi.nlm.nih.gov/32160554
Autor:
Toshihiro Nomura, Sofia V. Krause, Vytas P. Bindokas, Mitchell T. Hansen, Narayanan Kasthuri, Vandana Sampathkumar, Nicolase Y. Masse, Robert J. Andrew, Pierre De Rossi, Timothy F. Musial, Anis Contractor, David J. Freedman, Ha-Na Shim, Aleksandra J. Recupero, Daniel A. Nicholson, Ari Sudwarts, Gopal Thinakaran, Thomas Le Metayer
Publikováno v:
SSRN Electronic Journal.
BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer’s disease risk factor. Here, we investigated BIN1 function in the brain using conditional knockout (cKO) models. The loss of neuronal Bin1 expression resulted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d57d7b1b52e57f755d84e09fa8fcd2
https://doi.org/10.2139/ssrn.3443599
https://doi.org/10.2139/ssrn.3443599
Autor:
Shannon Faley, Reid W. D’Amico, James West, Ha-na Shim, Leon M. Bellan, Vineet Agrawal, Joanna R. Prosser
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2561 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 9
International Journal of Molecular Sciences
Volume 19
Issue 9
Endothelial dysfunction is a known consequence of bone morphogenetic protein type II receptor (BMPR2) mutations seen in pulmonary arterial hypertension (PAH). However, standard 2D cell culture models fail to mimic the mechanical environment seen in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c1f4d8aba5afeb007ce2302af3d698
http://www.mdpi.com/1422-0067/19/9/2561
http://www.mdpi.com/1422-0067/19/9/2561