Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Ha-Eun Choi"'
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Akademický článek
RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening
Autor: Shrestha Ghosh, Mileena T. Nguyen, Ha Eun Choi, Maximilian Stahl, Annemarie Luise Kühn, Sandra Van der Auwera, Hans J. Grabe, Henry Völzke, Georg Homuth, Samuel A. Myers, Cory M. Hogaboam, Imre Noth, Fernando J. Martinez, Gregory A. Petsko, Laurie H. Glimcher
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Telomere shortening is a prominent hallmark of aging and is emerging as a characteristic feature of Myelodysplastic Syndromes (MDS) and Idiopathic Pulmonary Fibrosis (IPF). Optimal telomerase activity prevents progressive shortening of telom
Externí odkaz: https://doaj.org/article/acac83437afc458ea79c24761644c96b
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8
Nonmuscle myosin IIB regulates Parkin-mediated mitophagy associated with amyotrophic lateral sclerosis-linked TDP-43
Autor: Soo-Kyung Lee, Jin-A Lee, You-Kyung Lee, Mi-Hee Jun, Jae-Woo Jang, Ha-Eun Choi, Sang-Hoon Lee, Jeongyeon Kim, Deok-Jin Jang, Haneul Choi, Pureum Jeon, Sang-Won Park
Publikováno v: Cell Death and Disease, Vol 11, Iss 11, Pp 1-8 (2020)
Cell Death & Disease
C-terminal fragments of Tar DNA-binding protein 43 (TDP-43) have been identified as the major pathological protein in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, how th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005b85efa8b181a212bf2669ba0e536e
http://link.springer.com/article/10.1038/s41419-020-03165-7
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9
Deciphering the molecular mechanisms underlying the plasma membrane targeting of PRMT8
Autor: Yong-Woo Jun, Jin-A Lee, Sang-Won Park, Ha-Eun Choi, Deok-Jin Jang
Publikováno v: BMB Reports
Arginine methylation plays crucial roles in many cellular functions including signal transduction, RNA transcription, and regulation of gene expression. Protein arginine methyltransferase 8 (PRMT8), a unique brain-specific protein, is localized to th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6805c4c66d2bf4c8cbbc97f0f6720bb
https://doi.org/10.5483/bmbrep.2019.52.10.272
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10
Development of LC 3/ GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy
Autor: Bong-Kiun Kaang, Yong-Woo Jun, Deok-Jin Jang, Jin-A Lee, You-Kyung Lee, Yang Hoon Huh, Ha-Eun Choi
Publikováno v: The EMBO Journal. 36:1100-1116
Macroautophagy allows for bulk degradation of cytosolic components in lysosomes. Overexpression of GFP/RFP‐LC3/GABARAP is commonly used to monitor autophagosomes, a hallmark of autophagy, despite artifacts related to their overexpression. Here, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d3cf2d9c4d6feecf876eb709483443
https://doi.org/10.15252/embj.201696315
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