AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.

Autor: Choksey A; Department of Physiology Anatomy and Genetics, University of Oxford, UK., Carter RD; Department of Physiology Anatomy and Genetics, University of Oxford, UK; Doctoral Training Centre, University of Oxford, Keble Road, Oxford, OX1 3NP, UK., Thackray BD; Department of Physiology Anatomy and Genetics, University of Oxford, UK., Ball V; Department of Physiology Anatomy and Genetics, University of Oxford, UK., Kennedy BWC; Department of Physiology Anatomy and Genetics, University of Oxford, UK; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK., Ha LHT; Department of Pharmacology, University of Oxford, UK., Sharma E; Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK., Broxholme J; Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK., Castro-Guarda M; Department of Physiology Anatomy and Genetics, University of Oxford, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, UK., Heather LC; Department of Physiology Anatomy and Genetics, University of Oxford, UK., Tyler DJ; Department of Physiology Anatomy and Genetics, University of Oxford, UK; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK., Timm KN; Department of Physiology Anatomy and Genetics, University of Oxford, UK; Department of Pharmacology, University of Oxford, UK. Electronic address: kerstin.timm@pharm.ox.ac.uk.

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2024 Jun; Vol. 191, pp. 12-22. Date of Electronic Publication: 2024 Apr 21.