Zobrazeno 1 - 10
of 74
pro vyhledávání: '"HWAI-SHI WANG"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Rheumatoid arthritis (RA) is characterized by synovial proliferation and lymphocyte accumulation leading to progressive damage of the periarticular bone and the articular cartilage. The hyperplasia of the synovial intima lining mainly consis
Externí odkaz:
https://doaj.org/article/c54e840261b04d3f9b422a9abf40a45e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Macrophages play an important role in the pathogenesis of rheumatoid arthritis (RA), in which the functions of pro-inflammatory macrophages (M1) and anti-inflammatory macrophages (M2) are different. Our previous studies have demonstrated tha
Externí odkaz:
https://doaj.org/article/51cb502c5bc54b32b9f34bf97759f17e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Breast cancer is the leading cause of cancer-related death for women. In breast cancer treatment, targeted therapy would be more effective and less harmful than radiotherapy or systemic chemotherapy. Tumor necrosis factor-related apoptosis-i
Externí odkaz:
https://doaj.org/article/fcf0f9776e4642c9966cb1624ccaf2f3
Autor:
Chun-Hao Chang, Yun-Li Lin, Yeu-Sheng Tyan, Yun-Hsuan Chiu, Ya-Han Liang, Chie-Pein Chen, Jiahn-Chun Wu, Hwai-Shi Wang
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252163 (2021)
Human umbilical cord Wharton's jelly derived mesenchymal stem cells (hUCMSCs), a source of cell therapy, have received a great deal of attention due to their homing or migrating ability in response to signals emanating from damaged sites. It has been
Externí odkaz:
https://doaj.org/article/a360cb78a52640ac94e8c7662cf4f5de
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-15 (2018)
Abstract Background Mesenchymal stem cells (MSCs) are known to home to injured and inflamed regions via the bloodstream to assist in tissue regeneration in response to signals of cellular damage. However, the factors and mechanisms that affect their
Externí odkaz:
https://doaj.org/article/7b1ba6fc36944875a442bc09dc68e10b
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The migration of administered mesenchymal stem cells (MSCs) to sites of injury via the bloodstream has been demonstrated. However, the underlying mechanisms of umbilical cord MSC adhesion to endothelial cells during transendothelial migration are sti
Externí odkaz:
https://doaj.org/article/8df63d2d28d34ace8d0deb3bd318de94
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear. In this study, we found that the proinfla
Externí odkaz:
https://doaj.org/article/aecf38fa42554e999044dd898307cf44
Autor:
Chun-Ming Shih, Chun-Yao Huang, Li-Rung Liao, Chiao-Po Hsu, Nai-Wen Tsao, Hwai-Shi Wang, Wei-Yuan Chen, Yea-Yang Su, Shing-Jong Lin, Chun-Che Shih, Feng-Yen Lin
Publikováno v:
Journal of the Formosan Medical Association, Vol 114, Iss 11, Pp 1088-1096 (2015)
Monocytes play important roles in inflammatory responses and vascular remodeling after vascular stenting. This research focused on impacts of nickel (Ni) ions released from a corroded cardiovascular stent on cytotoxicity and monocyte activation. Meth
Externí odkaz:
https://doaj.org/article/da700c5d693047119ea7f08f81d34e73
Autor:
Cheng-Yu Lin, Chia-Hua Zu, Chih-Chang Yang, Pei-Jiun Tsai, Jia-Fwu Shyu, Chie-Pein Chen, Zen-Chung Weng, Tien-Hua Chen M.D., Hwai-Shi Wang Ph.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Mesenchymal stem cells (MSCs) migrate via the bloodstream to sites of injury, possibly attracted by inflammatory cytokines. Although many cytokines can induce stem cell migration, the underlying mechanism is not fully understood. We found that tail v
Externí odkaz:
https://doaj.org/article/68a795d7cf3942d6ba2a713a0a1e9fc8
Autor:
Pei-Jiun Tsai, Hwai-Shi Wang, Gu-Jiun Lin, Shu-Cheng Chou, Tzu-Hui Chu, Wen-Ting Chuan, Ying-Jui Lu, Ying-Jui Weng, Cheng-Hsi Su, Po-Shiuan Hsieh, Huey-Kang Sytwu, Chi-Hung Lin, Tien-Hua Chen M.D., Jia-Fwu Shyu M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Type 1 diabetes mellitus is caused by T-cell-mediated autoimmune destruction of pancreatic β-cells. Systemic administration of mesenchymal stem cells (MSCs) brings about their incorporation into a variety of tissues with immunosuppressive effects, r
Externí odkaz:
https://doaj.org/article/c35c72ca174149478c8e6fb0b753eaba