Zobrazeno 1 - 10
of 97
pro vyhledávání: '"HUMAN-FETAL OVARY"'
Autor:
Maya R. Overland, Yi Li, Amber Derpinghaus, Sena Aksel, Mei Cao, Nicholas Ladwig, Gerald R. Cunha, Marta Himelreich-Perić, Laurence S. Baskin
A definition of normal human fetal and early postnatal ovarian development is critical to the ability to accurately diagnose the presence or absence of functional ovarian tissue in clinical specimens. Through assembling an extensive histologic and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063efe6bc090812e792ff54c796ffbb5
https://doi.org/10.1016/j.diff.2022.10.005
https://doi.org/10.1016/j.diff.2022.10.005
Autor:
Laetitia L Lecante, Sabrina Leverrier-Penna, Thomas Gicquel, Frank Giton, Nathalie Costet, Christèle Desdoits-Lethimonier, Laurianne Lesné, Bernard Fromenty, Vincent Lavoué, Antoine D Rolland, Séverine Mazaud-Guittot
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2022, 107 (6), pp.1647-1661. ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2022, ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, 2022, 107 (6), pp.1647-1661. ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2022, ⟨10.1210/clinem/dgac080⟩
Context Acetaminophen (APAP, paracetamol) is widely used by pregnant women. Although long considered safe, growing evidence indicates that APAP is an endocrine disruptor since in utero exposure may be associated with a higher risk of male genital tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c620e0bd4b6d4d74b06d25f54d6da0ab
https://hal.science/hal-03578173
https://hal.science/hal-03578173
Akademický článek
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Autor:
Yi Zhou, Yanni Feng, Lan Li, Shu-Hua Zou, Ze-Li Han, Xiao-Feng Sun, Wei Ge, Yong Zhao, Fan Yang, Massimo De Felici, Xun-Si Qin, Wei Shen, Shun-Feng Cheng
Publikováno v:
Aging (Albany NY)
In the present paper, we found that human fetal ovaries (at ~16 weeks) express the transcripts for several subunits of the nicotinic acetylcholine receptor (nAChR). Exposure to the drug in vitro resulted in the marked increase of apoptosis in the ova
Akademický článek
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Autor:
Signe Perlman, K. Harpelunde Poulsen, Rod T. Mitchell, John E Nielsen, Lene Lundvall, E. Rajpert-De Meyts, K Juul Hare, Hanne Frederiksen, A. Jørgensen, Cecilie Melau, L Langhoff Thuesen, Anders Juul
Publikováno v:
Harpelunde Poulsen, K, Nielsen, J E, Frederiksen, H, Melau, C, Juul Hare, K, Langhoff Thuesen, L, Perlman, S, Lundvall, L, Mitchell, R T, Juul, A, Rajpert-De Meyts, E & Jørgensen, A 2019, ' Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes ', Human Reproduction . https://doi.org/10.1093/humrep/dez191
Human Reproduction (Oxford, England)
Harpelunde Poulsen, K, Nielsen, J E, Frederiksen, H, Melau, C, Juul Hare, K, Langhoff Thuesen, L, Perlman, S, Lundvall, L, Mitchell, R T, Juul, A, Rajpert-De Meyts, E & Jørgensen, A 2019, ' Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes ', Human Reproduction, vol. 34, no. 11, pp. 2228-2243 . https://doi.org/10.1093/humrep/dez191
Human Reproduction (Oxford, England)
Harpelunde Poulsen, K, Nielsen, J E, Frederiksen, H, Melau, C, Juul Hare, K, Langhoff Thuesen, L, Perlman, S, Lundvall, L, Mitchell, R T, Juul, A, Rajpert-De Meyts, E & Jørgensen, A 2019, ' Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes ', Human Reproduction, vol. 34, no. 11, pp. 2228-2243 . https://doi.org/10.1093/humrep/dez191
STUDY QUESTION Does experimental manipulation of fibroblast growth factor 9 (FGF9)-signalling in human fetal gonads alter sex-specific gonadal differentiation? SUMMARY ANSWER Inhibition of FGFR signalling following SU5402 treatment impaired germ cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7185919c0ec26c9f99eec835c4422d4
https://hdl.handle.net/20.500.11820/99b177f5-4a5a-455f-9271-df348e438742
https://hdl.handle.net/20.500.11820/99b177f5-4a5a-455f-9271-df348e438742
Akademický článek
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Akademický článek
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Publikováno v:
Molecular Human Reproduction
Bayne, R A, Donnachie, D J, Kinnell, H L, Childs, A J & Anderson, R 2016, ' BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2 ', Molecular Human Reproduction . https://doi.org/10.1093/molehr/gaw044
Bayne, R A, Donnachie, D J, Kinnell, H L, Childs, A J & Anderson, R 2016, ' BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2 ', Molecular Human Reproduction . https://doi.org/10.1093/molehr/gaw044
STUDY QUESTION: Do changes in the expression of bone morphogenetic proteins (BMPs) 2 and 4, and their antagonists Gremlin1 (GREM1) and Gremlin2 (GREM2) during human fetal ovarian development impact on BMP pathway activity and lead to changes in gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::22d9ad46ee141b93f88fa44894a2c1e7
https://researchonline.rvc.ac.uk/id/eprint/10514/1/10514.pdf
https://researchonline.rvc.ac.uk/id/eprint/10514/1/10514.pdf
Autor:
He, Jing
Fetal germ cell development is a key stage of female reproductive life. The DAZ family proteins (DAZ, DAZL and BOLL) are RNA-binding proteins with critical roles in murine germ cell development but their expression and potential targets in the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______463::760d15c6a0a2d32a64f4a8d747bf5e95
http://hdl.handle.net/1842/25481
http://hdl.handle.net/1842/25481