Zobrazeno 1 - 10
of 9 450
pro vyhledávání: '"HUMAN ENDOTHELIAL-CELLS"'
Autor:
Jakub Slawski, Maciej Jaśkiewicz, Anna Barton, Sylwia Kozioł, James F. Collawn, Rafał Bartoszewski
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151386- (2024)
Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome for cells to survive hypoxic insults and oxidative stress. They are important during embryonic development and reprogram the cells to utilize glycolysis when
Externí odkaz:
https://doaj.org/article/a8db4514b4f84c12839ff955b08e8b07
Autor:
Heike Brendel, Jennifer Mittag, Anja Hofmann, Helene Hempel, Sindy Giebe, Patrick Diaba-Nuhoho, Steffen Wolk, Christian Reeps, Henning Morawietz, Coy Brunssen
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1178 (2024)
Aim: The primary endothelial NADPH oxidase isoform 4 (NOX4) is notably induced during hypoxia, with emerging evidence suggesting its vasoprotective role through H2O2 production. Therefore, we aimed to elucidate NOX4′s significance in endothelial fu
Externí odkaz:
https://doaj.org/article/665eb58dafb74c9d82a5012dd29931e5
Autor:
Ye Eun Choi, Jung Mo Yang, Chae Won Jeong, Sujin Shin, Junkyu Park, Kyungjin Lee, Ju Hyun Cho
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 926 (2024)
The incidence of cardiovascular diseases, such as high blood pressure, is increasing worldwide, owing to population aging and irregular lifestyle habits. Previous studies have reported the vasorelaxant effects of Prunus yedoensis bark methanol extrac
Externí odkaz:
https://doaj.org/article/5e6d52290d3a437fa1e8ea0dae513ffb
Autor:
Maciej Jaśkiewicz, Adrianna Moszyńska, Jarosław Króliczewski, Aleksandra Cabaj, Sylwia Bartoszewska, Agata Charzyńska, Magda Gebert, Michał Dąbrowski, James F. Collawn, Rafal Bartoszewski
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-19 (2022)
Abstract The hypoxia-inducible factors (HIF) are transcription factors that activate the adaptive hypoxic response when oxygen levels are low. The HIF transcriptional program increases oxygen delivery by inducing angiogenesis and by promoting metabol
Externí odkaz:
https://doaj.org/article/75c92cbadd1f4810a08902d147f250fb
Autor:
Jae Heon Kim, Sang Hong Bak, Hee Jo Yang, Seung Whan Doo, Do Kyung Kim, Won Jae Yang, Seung U. Kim, Hong J. Lee, Yun Seob Song
Publikováno v:
Basic and Clinical Andrology, Vol 32, Iss 1, Pp 1-11 (2022)
Résumé Contexte En raison de la différenciation limitée de l’endothélium à partir de cellules souches mésenchymateuses, il a été fortement recommandé d’utiliser des cellules progénitrices endothéliales pour la régénération de l’e
Externí odkaz:
https://doaj.org/article/49c537a1a51b43caa2044c4afe2fed39
Akademický článek
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Autor:
Nina Choublier, Meryam Taghi, Marie-Claude Menet, Morgane Le Gall, Johanna Bruce, Philippe Chafey, François Guillonneau, Amélie Moreau, Claire Denizot, Yannick Parmentier, Samir Nakib, Didier Borderie, Haniaa Bouzinba-Segard, Pierre-Olivier Couraud, Sandrine Bourdoulous, Xavier Declèves
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-24 (2022)
Abstract Endothelial cells (ECs) are constantly submitted in vivo to hemodynamical forces derived from the blood circulation, including shear stress (SS). ECs are able to detect SS and consequently adapt their phenotype, thus affecting many endotheli
Externí odkaz:
https://doaj.org/article/19fc31ee25ba4de8bf040d26425522eb
Publikováno v:
Experimental Gerontology, Vol 174, Iss , Pp 112127- (2023)
Senescent cells are key regulators of ageing and age-associated disease. MicroRNAs (miRs) are a key component of the molecular machinery governing cellular senescence, with several known to regulate important genes associated with this process.We sou
Externí odkaz:
https://doaj.org/article/3fbaf0b0ec904a9894f2220534270df1
Autor:
Maciej Jaśkiewicz, Adrianna Moszyńska, Marcin Serocki, Jarosław Króliczewski, Sylwia Bartoszewska, James F. Collawn, Rafal Bartoszewski
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 454-469 (2022)
The adaptive response to hypoxia involves the transcriptional induction of three transcription factors called hypoxia inducible factor alpha 1, 2 and 3 (HIF-1α, HIF-2α, and HIF-3α) which dimerize with constitutively expressed beta chains that toge
Externí odkaz:
https://doaj.org/article/fe0213f64af444338ce08c32f8a9c6ed
Akademický článek
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