Zobrazeno 1 - 10
of 272
pro vyhledávání: '"HUI-YUN WANG"'
Autor:
Chao-Yue Sun, Di Cao, Yue-Ning Wang, Nuo-Qing Weng, Qian-Nan Ren, Shuo-Cheng Wang, Mei-Yin Zhang, Shi-Juan Mai, Hui-Yun Wang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-13 (2024)
Abstract Repositioning approved antitumor drugs for different cancers is a cost-effective approach. Gilteritinib was FDA-approved for the treatment of FLT3-mutated acute myeloid leukemia in 2018. However, the therapeutic effects and mechanism of Gilt
Externí odkaz:
https://doaj.org/article/14ecd2f3492b4731b12eed8508ce51a2
Autor:
Qian-Nan Ren, Dan-Hui Huang, Xiao-Nan Zhang, Yue-Ning Wang, Yu-Feng Zhou, Mei-Yin Zhang, Shuo-Cheng Wang, Shi-Juan Mai, De-Hua Wu, Hui-Yun Wang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The androgen receptor (AR) plays an important role in male-dominant hepatocellular carcinoma, and specific acquired somatic mutations of AR have been observed in HCC patients. Our previous research have established the role of AR wild type a
Externí odkaz:
https://doaj.org/article/27788ad823be4a8ebdef13bb796654ba
Autor:
Jian-Ning Kang, Zheng-Fang Sun, Xin-Yu Li, Xiao-Di Zhang, Zheng-Xin Jin, Ce Zhang, Ying Zhang, Hui-Yun Wang, Na-Na Huang, Jian-Hao Jiang, Bin Ning
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1076-1083 (2023)
Studies have shown that gut microbiota metabolites can enter the central nervous system via the blood-spinal cord barrier and cause neuroinflammation, thus constituting secondary injury after spinal cord injury. To investigate the correlation between
Externí odkaz:
https://doaj.org/article/824865e198ed4ba99772946b984cfe85
Autor:
Dongni Chen, Hongli Zhou, Zhuochen Cai, Kaican Cai, Ji Liu, Weidong Wang, Huikai Miao, Hongmu Li, Rongzhen Li, Xiaodong Li, Youfang Chen, Hui-Yun Wang, Zhesheng Wen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-23 (2022)
Abstract Background Circular RNA (circRNA) has been recently identified as a critical regulator during carcinogenesis. However, the biological function and potential underlying mechanisms of circRNAs in lung cancer remain to be further elucidated. Me
Externí odkaz:
https://doaj.org/article/4f658a0e3ea44987bee2b8e979333200
Autor:
Rui-Qi Wang, Xiao-Ran Long, Ning-Ning Zhou, Dong-Ni Chen, Mei-Yin Zhang, Zhe-Sheng Wen, Lan-Jun Zhang, Fa-Zhong He, Zhi-Lin Zhou, Shi-Juan Mai, Hui-Yun Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Long non-coding RNAs (lncRNAs) play vital roles in the development and progression of non-small-cell lung cancer (NSCLC); however, the role of most lncRNAs in NSCLC remains unknown. This study explored the clinical significance, b
Externí odkaz:
https://doaj.org/article/7df4d752f9324a568549e9c8a07d8d2b
Autor:
Rui-Qi Wang, Xiao-Ran Long, Chun-Lei Ge, Mei-Yin Zhang, Long Huang, Ning-Ning Zhou, Yi Hu, Rui-Lei Li, Zhen Li, Dong-Ni Chen, Lan-Jun Zhang, Zhe-Sheng Wen, Shi-Juan Mai, Hui-Yun Wang
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Previous findings have indicated that the tumor, nodes, and metastases (TNM) staging system is not sufficient to accurately predict survival outcomes in patients with non-small lung carcinoma (NSCLC). Thus, this study aims to iden
Externí odkaz:
https://doaj.org/article/e4d28155b50b4b618db41c400bb7fc98
Autor:
Nuo-Qing Weng, Jun Chi, Jing Wen, Shi-Juan Mai, Mei-Yin Zhang, Long Huang, Ji Liu, Xian-Zi Yang, Guo-Liang Xu, Jian-Hua Fu, Hui-Yun Wang
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Long non-coding RNAs (lncRNAs) have been reported to be prognostic biomarkers in many types of cancer. We aimed to identify a lncRNA signature that can predict the prognosis in patients with esophageal squamous cell carcinoma (ESC
Externí odkaz:
https://doaj.org/article/5c6356791f9340bfbcf267bab23a6e0d
Autor:
Chao-Yue Sun, Di Cao, Qian-Nan Ren, Shan-Shan Zhang, Ning-Ning Zhou, Shi-Juan Mai, Bing Feng, Hui-Yun Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Aberrant activation of the Ras–ERK signaling pathway drives many important cancer phenotypes, and several inhibitors targeting such pathways are under investigation and/or approved by the FDA as single- or multi-agent therapy for patients with mela
Externí odkaz:
https://doaj.org/article/8e9ad77372b94b5aaa84552061dbf2ee
Autor:
Wen Wen, Shi-Juan Mai, Huan-Xin Lin, Mei-Yin Zhang, Jia-Ling Huang, Xin Hua, Chao Lin, Zhi-Qing Long, Zi-Jian Lu, Xiao-Qing Sun, Sai-Lan Liu, Qi Yang, Qian Zhu, Hui-Yun Wang, Ling Guo
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Early diagnosis is critical to reduce the mortality caused by nasopharyngeal carcinoma (NPC). MicroRNAs (miRNAs) are dysregulated and play important roles in carcinogenesis. Therefore, this study aimed to identify diagnostically r
Externí odkaz:
https://doaj.org/article/425ac3a2c45249c5a8605518b1d86e54
Publikováno v:
Chinese Journal of Cancer, Vol 36, Iss 1, Pp 1-10 (2017)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death, and new prognostic biomarkers are urgently needed. Apoptosis-stimulating P53-binding protein 1 (ASPP1) and 2 (ASPP2) have been reported to play
Externí odkaz:
https://doaj.org/article/76ca0b7f1dc4419d881062922289dd0e