Zobrazeno 1 - 10
of 5 600
pro vyhledávání: '"HU LEI"'
Autor:
Yingying Wang, Youping Zhang, Hao Luo, Wei Wei, Wanting Liu, Weiwei Wang, Yunzhao Wu, Cheng Peng, Yanjie Ji, Jianfang Zhang, Chujiao Zhu, Wenhui Bai, Li Xia, Hu Lei, Hanzhang Xu, Leimiao Yin, Wei Weng, Li Yang, Ligen Liu, Aiwu Zhou, Yueyue Wei, Qi Zhu, Weiliang Zhu, Yongqing Yang, Zhijian Xu, Yingli Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5235-5248 (2024)
Inducing the degradation of KRAS represents a novel strategy to combat cancers with KRAS mutation. In this study, we identify ubiquitin-specific protease 2 (USP2) as a novel deubiquitinating enzyme of KRAS in multiple myeloma (MM). Specifically, we d
Externí odkaz:
https://doaj.org/article/d986029b2c5440409f127305b35e13e2
Publikováno v:
Qixiang keji, Vol 52, Iss 5, Pp 753-761 (2024)
This study uses litchi from Conghua and Zengcheng regions in Guangzhou as insurance targets, and combines the meteorological disasters throughout the entire growth period of litchi to design litchi meteorological index insurance products and verify i
Externí odkaz:
https://doaj.org/article/dc22ed328e894b0d8e910f23df4ff457
Autor:
Xingming Zhang, Lou Geng, Yi Tang, Yingying Wang, Youping Zhang, Chujiao Zhu, Hu Lei, Hanzhang Xu, Qi Zhu, Yingli Wu, Wenli Gu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Aberrant upregulation of the ubiquitin-specific protease 14 (USP14) has been found in some malignant tumors, including oral squamous cell carcinoma (OSCC). In this study, we further demonstrated that aberrantly overexpressed USP14 was also c
Externí odkaz:
https://doaj.org/article/7b27daded76546458e3365984e7fa120
Publikováno v:
Jixie chuandong, Pp 1-8 (2024)
Yaw bearings and slewing bearings in wind turbine systems, rotating support bearings in aerospace launch towers, and slew bearings in cranes and excavators all exhibit characteristics of low-speed reciprocating motion. Diagnosing faults in low-speed
Externí odkaz:
https://doaj.org/article/f7167fe159964090b2636108ac057246
Publikováno v:
Xibei Gongye Daxue Xuebao, Vol 41, Iss 3, Pp 546-556 (2023)
This paper focuses on the network equipment fault monitoring and diagnosis software, and studies the fault diagnosis of the monitored AFDX network based on the network algorithm. Firstly, the range fault characteristic parameters are designed to iden
Externí odkaz:
https://doaj.org/article/74872a575a3b41c5a64ee7edae7f1ea3
Publikováno v:
Waike lilun yu shijian, Vol 28, Iss 01, Pp 77-82 (2023)
Objective To investigate the feasibility and effect of simple support bracket combined with one stitch suture in terminal ileostomy of two stomas during anus-preserving radical resection in low rectal cancer patients. Methods Retrospectively analysis
Externí odkaz:
https://doaj.org/article/e82520ab87524cbc8569d4f34f40e586
Publikováno v:
Rock and Soil Mechanics, Vol 43, Iss 9, Pp 2568-2580 (2022)
In the Wuxia section of the Three Gorges Reservoir area, it is found that there are many deformation signs of sliding-bending along the bedding bank slope, and the cyclic fluctuation of reservoir water worsens the deterioration and instability of the
Externí odkaz:
https://doaj.org/article/bd766589cbf04d58bea4003089ec37eb
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-4 (2022)
Abstract Pyruvate kinase M2 (PKM2) plays an important role in the metabolism and proliferation of leukemia cells. Here, we show that deubiquitinase JOSD2, a novel tumor suppressor, blocks PKM2 nuclear localization by reducing its K433 acetylation in
Externí odkaz:
https://doaj.org/article/457f9b36d83141fa80e00318f326897e
Autor:
Xu, Zhong, Huang, Jun, Wu, Hongyan, Chen, Rui, Zhang, Chengyuan, Xu, Zaifeng, Zhang, Weixin, Hu, Lei, Zhang, Bin
High silicon steel with 6.5% silicon content is the best because of its excellent magnetic properties, such as high saturation magnetization, high resistivity, low iron loss and near zero magnetostriction. High silicon steel can greatly save energy,
Externí odkaz:
http://arxiv.org/abs/2412.11481
The short-lived ionized emission lines in early spectroscopy of the nearby type II supernova SN 2024ggi signify the presence of dense circumstellar matter (CSM) close to its progenitor star. We proposed the Atacama Large Millimeter/submillimeter Arra
Externí odkaz:
http://arxiv.org/abs/2412.11389