Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

Autor: David Križaj, Trine Lisberg Toft-Bertelsen, Michael H. Elliott, Nanna MacAulay, Paul S. Bernstein, Grace F. Hoffmann, Eric Enyong, Aruna Gorusupudi, Amy Lin, Monika Lakk

Publikováno v: Lakk, M, Hoffmann, G F, Gorusupudi, A, Enyong, E, Lin, A, Bernstein, P S, Toft-Bertelsen, T, MacAulay, N, Elliott, M H & Krizaj, D 2021, ' Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension ', Journal of Lipid Research, vol. 62 . https://doi.org/10.1016/j.jlr.2021.100145
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100145-(2021)

Despite the association of cholesterol with debilitating pressure-related diseases such as glaucoma, heart disease, and diabetes, its role in mechanotransduction is not well understood. We investigated the relationship between mechanical strain, free

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https://curis.ku.dk/ws/files/286483858/Membrane_cholesterol_regulates_TRPV4_function_cytoskeletal_expression_and_the_cellular_response_to_tension.pdf