Zobrazeno 1 - 10
of 203
pro vyhledávání: '"HSPB5"'
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 12, Pp 2638-2644 (2023)
Stroke-induced immunosuppression is a process that leads to peripheral suppression of the immune system after a stroke and belongs to the central nervous system injury-induced immunosuppressive syndrome. Stroke-induced immunosuppression leads to incr
Externí odkaz:
https://doaj.org/article/fbc57b27c3c04e0da2d1b584ddf01f81
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Background Lupus nephritis (LN) is an inflammatory disease of the kidneys affecting patients with systemic lupus erythematosus. Current immunosuppressive and cytotoxic therapies are associated with serious side effects and fail to protect 20
Externí odkaz:
https://doaj.org/article/1975ec031a404180979208014f141c1f
Publikováno v:
Autoimmunity, Vol 55, Iss 3, Pp 192-202 (2022)
Lupus nephritis (LN) is a common and serious complication of systemic lupus erythematosus. The current treatments for LN are accompanied with severe immunotoxicity and have limits of effectiveness. Since our in vitro experiments demonstrated that a s
Externí odkaz:
https://doaj.org/article/0b1fb4c3191d450bb0033463c00bd0d0
Autor:
Jing Li, Jingjing Yu, Wenxian Xue, Huili Huang, Longjun Yan, Fan Sang, Shuangshuang An, Jing Zhang, Mingli Wang, Jun Zhang, Hui Li, Xiukun Cui, Jiang He, Yanzhong Hu
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background HSPB5 is an ATP-independent molecular chaperone that is induced by heat shock or other proteotoxic stresses. HSPB5 is cytoprotective against stress both intracellularly and extracellularly. It acts as a potential therapeutic candi
Externí odkaz:
https://doaj.org/article/77a0c955934f4560a18731a931337a14
Autor:
Julie Tanguy, Pierre-Marie Boutanquoi, Olivier Burgy, Lucile Dondaine, Guillaume Beltramo, Burhan Uyanik, Carmen Garrido, Philippe Bonniaud, Pierre-Simon Bellaye, Françoise Goirand
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 177 (2023)
Idiopathic pulmonary fibrosis is a chronic, progressive and lethal disease of unknown etiology that ranks among the most frequent interstitial lung diseases. Idiopathic pulmonary fibrosis is characterized by dysregulated healing mechanisms that lead
Externí odkaz:
https://doaj.org/article/9aeb91d5396c4736a7d0ce719f5f6fe0
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Ana T. Marcos, Diego Amorós, Beatriz Muñoz-Cabello, Francisco Galán, Eloy Rivas Infante, Luis Alcaraz‐Mas, José M. Navarro‐Pando
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)
Abstract Background αB‐crystallin is a promiscuous protein involved in numerous cell functions. Mutations in CRYAB have been found in patients with different pathological phenotypes that are not properly understood. Patients can present different
Externí odkaz:
https://doaj.org/article/59e8a4d44c2443178dfce3ea3560b930
Autor:
Silvia T. Erni, Gabriella Fernandes, Michelle Buri, Michael Perny, Rolf Jan Rutten, Johannes M. van Noort, Pascal Senn, Denis Grandgirard, Marta Roccio, Stephen L. Leib
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Sensorineural hearing loss is the most common long-term deficit after pneumococcal meningitis (PM), occurring in up to 30% of surviving patients. The infection and the following overshooting inflammatory host response damage the vulnerable sensory ce
Externí odkaz:
https://doaj.org/article/2bc8416081e34a35ac71fa5bb7b139d3