Zobrazeno 1 - 3
of 3
pro vyhledávání: '"HSP90-CDC37 chaperone complex"'
Autor:
Daniel C. Lee, Sheeba Varghese-Gupta, Malathi Narayan, Chelsea Gibson, Umesh K. Jinwal, Kaitlyn Braswell, Juan Zhang, Ashley Zitnyar
Publikováno v:
Current Aging Science. 8:259-265
Leucine-Rich Repeat Kinase 2 (LRRK2) is a large, multi-domain protein that has been found to be mutated in patients with familial and sporadic Parkinson's disease, Alzheimer's disease and Crohn's disease. While the functions of LRRK2 are still largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ce8ba6a80f68cabce2094b242b9c0f
https://doi.org/10.2174/1874609808666150520111109
https://doi.org/10.2174/1874609808666150520111109
Autor:
Kristie L. Rose, Der-Fen Suen, Ji Zhang, Mondira Kundu, Do Hyung Kim, Frank C. Dorsey, Chang Hwa Jung, Stephanie M. Prater, Joung Hyuck Joo, Kristin M. Hennessy-Walters, Meredith A. Steeves, Rekha Iyengar, John L. Cleveland, Craig B. Thompson, Kelly McCastlain, Chia Ying Yang, Richard J. Youle, Paul A. Ney, Aashish Joshi
Publikováno v:
Molecular Cell. 43(4):572-585
Autophagy, the primary recycling pathway of cells, plays a critical role in mitochondrial quality control under normal growth conditions and in the response to cellular stress. The Hsp90-Cdc37 chaperone complex coordinately regulates the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c4d3e39a2f8ba4534ec4923f045eba
Publikováno v:
Circulation Research. 106:1404-1412
Rationale : p38 is an important stress activated protein kinase involved in gene regulation, proliferation, differentiation, and cell death regulation in heart. p38 kinase activity can be induced through canonical pathway via upstream kinases or by n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d0ed63c1813445a45c0d59ad2d7e94
https://doi.org/10.1161/circresaha.109.213769
https://doi.org/10.1161/circresaha.109.213769