Zobrazeno 1 - 4
of 4
pro vyhledávání: '"HSP40 Heat-Shock Protein"'
Autor:
Yulya S. Itkis, Maja Hempel, Ben Pode-Shakked, Piero Barboni, N.L. Sheremet, Polina G. Tsygankova, Riccardo Berutti, Valerio Carelli, Chiara La Morgia, Daniele Ghezzi, Leonardo Caporali, Jean-Michel Rozet, Natalia A. Andreeva, Amelie T van der Ven, Peter Charbel Issa, Wolfram S. Kunz, Sarah L. Stenton, Claudia B. Catarino, Johannes A. Mayr, Matias Wagner, Maria Lucia Cascavilla, Flavia Palombo, Reka Kovacs-Nagy, Ilka Wittig, Alessandra Maresca, Pedro Felipe Malacarne, Thomas Klopstock, Costanza Lamperti, Sylvie Gerber, Cornelia Kornblum, Holger Prokisch, Nino V. Zhorzholadze, Jana Meisterknecht, Robert Kopajtich, Tatiana A. Nevinitsyna, Ekaterina Zakharova, Michele Carbonelli, Tatiana D. Krylova, Michal Tzadok, Elisabeth Graf, Zahra Assouline, Francesca Tagliavini, Josseline Kaplan, Maria S. Shmelkova, Mariantonietta Capristo, Elise Héon, Ortal Barel, Peter Freisinger, Elisheva Javasky, Igor Bychkov, Christina Ludwig, Tim M. Strom, Catherine Vignal-Clermont, Juliana Heidler
Publikováno v:
The journal of clinical investigation 131(6), e138267 (2021). doi:10.1172/JCI138267
J Clin Invest
J Clin Invest
Leber's hereditary optic neuropathy (LHON) is the most frequent mitochondrial disease and was the first to be genetically defined by a point mutation in mitochondrial DNA (mtDNA). A molecular diagnosis is achieved in up to 95% of cases, the vast majo
Autor:
Lampis, Andrea, Carotenuto, Pietro, Vlachogiannis, Georgios, Cascione, Luciano, Hedayat, Somaieh, Burke, Rosemary, Clarke, Paul, Bosma, Else, Simbolo, Michele, Scarpa, Aldo, Yu, Sijia, Cole, Rebecca, Smyth, Elizabeth, Mateos, Javier Fernández, Begum, Ruwaida, Hezelova, Blanka, Eltahir, Zakaria, Wotherspoon, Andrew, Fotiadis, Nicos, Bali, Maria Antonietta, Nepal, Chirag, Khan, Khurum, Stubbs, Mark, Hahne, Jens C., Gasparini, Pierluigi, Guzzardo, Vincenza, Croce, Carlo M., Eccles, Suzanne, Fassan, Matteo, Cunningham, David, Andersen, Jesper B., Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publikováno v:
Lampis, A, Carotenuto, P, Vlachogiannis, G, Cascione, L, Hedayat, S, Burke, R, Clarke, P, Bosma, E, Simbolo, M, Scarpa, A, Yu, S, Cole, R, Smyth, E, Mateos, J F, Begum, R, Hezelova, B, Eltahir, Z, Wotherspoon, A, Fotiadis, N, Bali, M A, Nepal, C, Khan, K, Stubbs, M, Hahne, J C, Gasparini, P, Guzzardo, V, Croce, C M, Eccles, S, Fassan, M, Cunningham, D, Andersen, J B, Workman, P, Valeri, N & Braconi, C 2018, ' MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma ', Gastroenterology, vol. 154, no. 4, pp. 1066-1079 . https://doi.org/10.1053/j.gastro.2017.10.043
Gastroenterology
Gastroenterology
Background & Aims: \ud Cholangiocarcinomas (CCA) are resistant to chemotherapy, so new therapeutic agents are needed. We performed a screen to identify small-molecule compounds that are active against CCAs. Levels of microRNA 21 (MIR21 or miRNA21) ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4bf3a50be8e84d4ccf725810cb52189c
http://hdl.handle.net/11562/969672
http://hdl.handle.net/11562/969672
Autor:
M. Angela Nieto, Giuseppe Merla, Santina Venuto, Eva Rodriguez-Aznar, Giuseppe Borsani, Tommaso Mazza, Eugenio Monti, Juan Galceran, Lucia Micale, Stefano Castellana, Marta Manzoni, Carmela Rinaldi, Barbara Mandriani
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports
To orchestrate the genomic response to cellular stress signals, p53 recognizes and binds to DNA containing specific and well-characterized p53-responsive elements (REs). Differences in RE sequences can strongly affect the p53 transactivation capacity
Autor:
J. L. Nelson, D. A. Weber, E. C. Keystone, W. E R Ollier, Dennis A. Carson, Alberto Martini, A. C. Montemayor, Carlomaurizio Montecucco, A. La Cava, Salvatore Albani
Publikováno v:
Nature medicine. 1(5)
A novel ‘multistep molecular mimicry’ mechanism for induction of rheumatoid arthritis (RA) by bacterial antigens that activate T lymphocytes previously ‘educated’ by peptides derived from a class of human histocompatibility antigens is report