Zobrazeno 1 - 10
of 303
pro vyhledávání: '"HSF-1"'
Publikováno v:
In Neuropharmacology 15 March 2025 266
Autor:
Jichang Huang, Kai Wang, Mengqing Wang, Zhen Wu, Guangjie Xie, Yuling Peng, Yan Zhang, Xumin Zhang, Zhiyong Shao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 495-505 (2023)
Environmental factors, including temperature, can modulate an animal’s lifespan. However, their underlying mechanisms remain largely undefined. We observed a profound effect of temperature on the aging of Caenorhabditis elegans (C. elegans) by perf
Externí odkaz:
https://doaj.org/article/63bb86131b904832b7a66d7961bf9e60
Publikováno v:
Experimental Gerontology, Vol 174, Iss , Pp 112131- (2023)
Zhuyeqing liquor (ZYQL) is well-known traditional functional liquor in China that contains twelve crude drugs. Studies have shown that ZYQL has many beneficial effects, but its anti-aging effect has not been reported. Here, we found that ZYQL had exc
Externí odkaz:
https://doaj.org/article/5bdc9c8e26754ee392108ee25b1913d1
HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network
Autor:
Maria I. Lazaro-Pena, Zachary C. Ward, Sifan Yang, Alexandra Strohm, Alyssa K. Merrill, Celia A. Soto, Andrew V. Samuelson
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Discoveries made in the nematode Caenorhabditis elegans revealed that aging is under genetic control. Since these transformative initial studies, C. elegans has become a premier model system for aging research. Critically, the genes, pathways, and pr
Externí odkaz:
https://doaj.org/article/3518703fb6c7441ca904dcc0299d11cc
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
The decline of proteostasis is a hallmark of aging that is, in part, affected by the dysregulation of the heat shock response (HSR), a highly conserved cellular response to proteotoxic stress in the cell. The heat shock transcription factor HSF-1 is
Externí odkaz:
https://doaj.org/article/581c67e35d0b466c8de27306de21ed55
Akademický článek
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Autor:
Haitao Zhou, Shanshan Ding, Chuanxin Sun, Jiahui Fu, Dong Yang, Xi'e Wang, Chih-chen Wang, Lei Wang
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Lycium barbarum berry (Ningxia Gouqi, Fructus lycii, goji berry, or wolfberry), as a traditional Chinese herb, was recorded beneficial for longevity in traditional Chinese medical scriptures and currently is a natural dietary supplement worldwide. Ho
Externí odkaz:
https://doaj.org/article/f398f58f265b4f6ab2b4fc4d99615f65
Akademický článek
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Publikováno v:
eLife, Vol 8 (2019)
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stres
Externí odkaz:
https://doaj.org/article/51a8ef5c3f8143ca8b1b50910b81b7ec
Autor:
Neeraja M. Krishnan, Hiroto Katoh, Vinayak Palve, Manisha Pareek, Reiko Sato, Shumpei Ishikawa, Binay Panda
Publikováno v:
PeerJ, Vol 7, p e6464 (2019)
Tumor suppression by the extracts of Azadirachta indica (neem) works via anti-proliferation, cell cycle arrest, and apoptosis, demonstrated previously using cancer cell lines and live animal models. However, very little is known about the molecular t
Externí odkaz:
https://doaj.org/article/0ca594abd4ef4556b3efd25b12df7c6d