Zobrazeno 1 - 10
of 141
pro vyhledávání: '"HSD11B1"'
Autor:
Sabrina E. Wang, Vivian Viallon, Matthew Lee, Niki Dimou, Fergus Hamilton, Carine Biessy, Tracy O'Mara, Maria Kyrgiou, Emma J. Crosbie, Therese Truong, Gianluca Severi, Rudolf Kaaks, Renée Turzanski Fortner, Matthias B. Schulze, Benedetta Bendinelli, Sieri Sabina, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, Marta Crous-Bou, Maria-Jose Sánchez, Amaia Aizpurua, Daniel Rodriguez Palacios, Marcela Guevara, Ruth C. Travis, Konstantinos K. Tsilidis, Alicia Heath, James Yarmolinsky, Sabina Rinaldi, Marc J. Gunter, Laure Dossus
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105341- (2024)
Summary: Background: Inflammation and immune dysregulation are hypothesized contributors to endometrial carcinogenesis; however, the precise underlying mechanisms remain unclear. Methods: We measured pre-diagnostically 152 plasma protein biomarkers i
Externí odkaz:
https://doaj.org/article/141e8b2518434ea088f93b8aa644b8af
Publikováno v:
Gynecological Endocrinology, Vol 40, Iss 1 (2024)
Aims This study aims to explore the alterations of dendritic cells (DCs) subpopulations in ectopic endometrial lesions and unveil the underlying mechanisms.Materials and methods Patients with endometriosis (n = 81) and women without endometriosis (n
Externí odkaz:
https://doaj.org/article/8b16b41af0cc4149936c4e0e4312cf19
Autor:
Hélène Poinot, Eloïse Dupuychaffray, Grégoire Arnoux, Montserrat Alvarez, Jérémie Tachet, Ounss Ezzar, Jonathan Moore, Olivia Bejuy, Eulalia Olesti, Gioele Visconti, Víctor González-Ruiz, Serge Rudaz, Jean-Christophe Tille, Clarissa D. Voegel, Patrycja Nowak-Sliwinska, Carole Bourquin, Aurélien Pommier
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTAlthough immune-based therapies have revolutionized the management of cancer, novel approaches are urgently needed to improve their outcome. We investigated the role of endogenous steroids in the resistance to cancer immunotherapy, as these h
Externí odkaz:
https://doaj.org/article/419652ef65f04df7a05ec68d586aacf1
Autor:
Alejandro Lomniczi, Selva L. Luna, Rita Cervera-Juanes, Maria-Luisa Appleman, Steven G. Kohama, Henryk F. Urbanski
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionThe hippocampus is especially susceptible to age-associated neuronal pathologies, and there is concern that the age-associated rise in cortisol secretion from the adrenal gland may contribute to their etiology. Furthermore, because 11β-h
Externí odkaz:
https://doaj.org/article/32e8e7987f654b6eab34aa0fcfdb61e8
Autor:
Memory MUKANGWA, Masafumi TETSUKA
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 4, Pp 206-213 (2023)
Progesterone (P4) and cortisol production increase in luteinized granulosa cells (LGCs) during the periovulatory period, but their interaction is not well established. Therefore, we investigated their interaction in cultured bovine LGCs. Granulosa ce
Externí odkaz:
https://doaj.org/article/ee7a5504a8504b6688dfd5f02f3c8ca8
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Akademický článek
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Akademický článek
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Publikováno v:
Poultry Science, Vol 99, Iss 11, Pp 6075-6083 (2020)
The aim of this study was to determine the molecular mechanism of miR-205b targeting 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1) on the apoptosis and proliferation of granulosa cells (GC) of pigeons. Our previous studies suggested that HSD11B1
Externí odkaz:
https://doaj.org/article/1e08132633644b8fb2c2572cb4ab6976
Publikováno v:
Zanco Journal of Pure and Applied Sciences, Vol 31, Iss 5, Pp 36-43 (2019)
Background: Polycystic ovarian syndrome (PCOS) is one of the most prevalent gynaecological imbalances of endocrine hormones and metabolic disorders that affect women during puberty, with a prevalence of up to 17.8%. Objective: The current study fo
Externí odkaz:
https://doaj.org/article/6fa349e9b3cc4f69b012bce66f685a19